A preparation method of Ganoderma lucidum extract

Abstract

A preparation method of ganoderma lucidum extract, the preparation process of which is as follows: the raw material of ganoderma lucidum fruiting body is washed to remove impurities, dried, coarsely crushed, and then ultrafinely pulverized; continuous countercurrent ultrasonic extraction, the extract is subjected to adsorption, centrifugation, ultrafiltration or coagulation Gel column chromatography, concentration and drying to obtain the product of the present invention. The preparation method provided by the invention can not only effectively remove harmful substances such as heavy metals and pesticide residues in products, but also effectively purify and protect active components; the raw material utilization rate is high, the process is simple, the environment is friendly, and industrial production is easy to realize. The product prepared by the method has the characteristics of light color, high active ingredient content, strong biological activity, low pesticide residue and low heavy metal, and has good market prospects in the fields of nutrition and health care, food and beverage, and daily chemical industry.

Description

technical field [0001] The invention relates to a preparation method of ganoderma lucidum extract, in particular to an extraction and separation process of active components in ganoderma lucidum. Background technique [0002] Ganoderma lucidum is the dry fruiting body of Ganoderma Lucidum Karst or Ganodermasinense Zhao, Xu et Zhang, a fungus of the genus Ganoderma in the family Polyporaceae. It is mainly distributed in Zhejiang, Heilongjiang, Jilin, Anhui, Jiangxi, Hunan, Guizhou, Guangdong, and Fujian in China. and so on. Ganoderma lucidum is rich in polysaccharides, nucleosides, amino acids, triterpenes and other active ingredients. Pharmacological studies have shown that Ganoderma lucidum has activities such as regulating immunity, anti-tumor, and anti-aging. At present, there are more than 200 kinds of Ganoderma lucidum polysaccharides, most of which are β-glucans, and a few are α-glucans. Generally speaking, the longer the main chain of Ganoderma lucidum polysaccharid...

AI Technical Summary

Problems solved by technology

The process uses macroporous resin to treat the triterpenoids of Ganoderma lucidum, which has a certain effect of purification and impurity removal; pure water is used to extract the polysaccharides of Ganoderma lucidum in the alcohol extraction filter residue of Ganoderma lucidum, so that the resources are fully utilized; The heat-sensitive active ingredient-Ganoderma lucidum polysaccharide has not taken protective measures, the degradation loss of the polysaccharide component of the ganoderma lucidum is large, and the biological activity of the product is affected; the influence of the molecular weight of the polysaccharide of the ganoderma lucidum on the activity of the product is not fully considered in the process, and the harmful effects of pesticide residues and heavy metals are not considered. The impact of the substance on the biological activity and application of the product, there are certain defects in the process, and the application of the final product also has certain limitations

[0007] The existing technology lacks a systematic technical solution to simultaneously solve many key issues such as the utilization rate of ganoderma lucidum raw materials, the extraction rate, retention rate and biological activity of ganoderma lucidum bioactive components, pesticide residues, heavy metal residues, environmental and social benefits, etc.

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