Method for separating alcohol in alcohol ester mixture by using deep eutectic solvent

Abstract

The invention discloses a method for separating alcohol in an alcohol ester mixture by using a deep eutectic solvent. The method comprises the following steps: step 1, mixing choline chloride and p-toluenesulfonic acid according to a molar ratio of 1: (0.5-1.5) to obtain the deep eutectic solvent; and step 2, mixing the obtained deep eutectic solvent and an isoamyl alcohol-isoamyl acetate mixtureaccording to a solid-liquid ratio of (2.5-4): 1, wherein the isoamyl alcohol-isoamyl acetate mixture has an alcohol-ester molar ratio of 1: (1.5-3.5), performing extraction, and taking out an upper-phase solution so as to separate isoamyl alcohol in the alcohol-ester mixture. According to the invention, the deep eutectic solvent obtained by mixing choline chloride and p-toluenesulfonic acid according to a certain ratio is used for extracting the isoamyl alcohol-isoamyl acetate mixture, and the solid-liquid ratio of the deep eutectic solvent to the alcohol ester mixture and the alcohol-ester ratio of the alcohol ester mixture are optimized, so extraction efficiency can be greatly improved, and optimal extraction efficiency can reach 57% or more; and the method is suitable for industrial production and can realize green chemistry.

Description

technical field [0001] The invention relates to the technical field of separation and purification of organic mixtures, more specifically, the invention relates to a method for separating alcohols in alcohol-ester mixtures using a deep eutectic solvent. Background technique [0002] Deep eutectic solvent refers to a two-component or multi-component combination of hydrogen bond acceptors (quaternary ammonium salts, zwitterions, etc.) and hydrogen bond donors (acids, sugars, alcohols, etc.) in a certain ratio Choline deep eutectic solvent is a kind of deep eutectic solvent, which is formed by hydrogen bond acceptor choline chloride and hydrogen bond donor (acids, sugars, alcohols, etc.) It is a kind of deep eutectic solvent formed by proportioning combination. [0003] The research results of deep eutectic solvents were first reported by Abbott et al. in 2003. They are similar to ionic liquids but have a wider range of applications than ionic liquids. Most of deep eutectic so...

AI Technical Summary

Problems solved by technology

[0004] When preparing isoamyl acetate, because it cannot be completely volatilized, there will be a small amount of isoamyl alcohol raw material residue in the product, so it is difficult to achieve purity. It is necessary to take a certain method to separate alcohol and ester, but due to the low content of isoamyl alcohol, it is limited The separation method is not clear, which affects the purity of isoamyl acetate, which is a difficult point in the purification process of isoamyl acetate

Studies have shown that choline-based deep eutectic solvents have certain extraction and separation effects on alcohols in organic matter, but there is still a lack of efficient and stable extraction methods for alcohols in alcohol-ester mixtures using choline-based deep eutectic solvents. Realize the wide application of deep eutectic solvent as a new green solvent in the separation of alcohol and ester

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