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Liquid dressing and preparing method thereof

A technology of liquid dressing and formula, which is applied in medical formula, medical science, drug delivery, etc. It can solve the problems of low water vapor transmission rate and achieve low water diffusion properties, rapid and effective hemostasis, and fast film formation.

Inactive Publication Date: 2019-10-25
绍兴百立康医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The liquid dressing uses polyvinyl alcohol resin as a film-forming substance, which has a fast film-forming speed and can be isolated and waterproof, but has the disadvantage of low water vapor transmission rate.

Method used

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  • Liquid dressing and preparing method thereof
  • Liquid dressing and preparing method thereof
  • Liquid dressing and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] (1) In a dry environment at room temperature, weigh 30g of α-butyl cyanoacrylate, 40g of silicon dioxide, 18g of ether, 1.5g of anhydrous citric acid and 0.5g of salicylic acid, and mix them evenly.

[0030] (2) In a dry environment at room temperature, the cans of the liquid dressing prepared in step (1) are filled into aluminum aerosol cans, and high-pressure nitrogen is used as a propellant.

[0031] The closed environment refers to a closed stirred tank at 20-25°C under the protection of dry gas, wherein the controlled drying environment is a temperature of 20-25°C and a relative humidity of 5-15%.

Embodiment 2

[0033] (1) In a dry environment at room temperature, weigh 30g α-butyl cyanoacrylate, 40g α-octyl cyanoacrylate, 10g silicon dioxide, 17.9g ether, 2g anhydrous citric acid and 0.1g salicylic acid, mix uniform.

[0034] (2) In a dry environment at room temperature, the cans of the liquid dressing prepared in step (1) are filled into aluminum aerosol cans, and high-pressure nitrogen is used as a propellant.

Embodiment 3

[0036] (1) In a dry environment at room temperature, weigh 40g of α-octyl cyanoacrylate, 19.5g of silicon dioxide, 40g of ether, 0.1g of anhydrous citric acid and 0.4g of salicylic acid, and mix them evenly.

[0037](2) In a dry environment at room temperature, the cans of the liquid dressing prepared in step (1) are filled into aluminum aerosol cans, and high-pressure nitrogen is used as a propellant.

[0038] Control group 1: Choose similar products that are already on the market. The product used in this control group is Minrong Machinery Equipment 20170034. The main components are acrylic resin, acetyl tributyl citrate, and ethanol.

[0039] Control group 2: Choose similar products already on the market. The product selected in this control group is Sujizhun 20170080. The main components are propylene hydrochloride copolymer, glycerin, Tween 80, triethyl citrate, ethanol, and purified water. composition.

[0040] Control group 3: In a dry environment at room temperature, ...

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Abstract

The invention provides a liquid dressing. The liquid dressing comprises, by weight, 30-70% of alpha-cyanoacrylate, 10-40% of silicon dioxide, 15-40% of diethyl ether, 0.1-2% of anhydrous citric acid and 0.1-0.5% of salicylic acid according to the total formula component percentage of 100%. The liquid dressing has the effects of rapid film forming, high vapor permeability and good waterproofness.

Description

technical field [0001] The invention relates to a dressing and a preparation method thereof, in particular to a liquid dressing and a preparation method thereof. Background technique [0002] Traditional band-aids have the functions of stopping bleeding, protecting wounds, absorbing exudates, and keeping wounds dry. Their shortcomings are also obvious, such as the inability to avoid wound scabs, poor waterproof and vapor permeability, etc., and cannot meet the special needs of patients. As a modern medical dressing, liquid dressing is mainly made of raw materials such as biocompatible polymers, volatile solvents, and antibacterial agents. Liquid dressings have the advantages of no scab on the wound surface, protection of the wound surface to promote wound healing, waterproof, seepage-proof and infection-proof, etc. The film-forming substances of domestic liquid dressings are mostly acrylic resins, polyurethane resins or polyvinyl alcohol resins, which not only have low wate...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/00A61L26/0004A61L26/0061A61L26/0066A61L26/009A61L2300/404A61L2300/412A61L2400/04
Inventor 徐意金伟伟徐佳南
Owner 绍兴百立康医疗科技有限公司
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