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Bioactive sustained-release composition

A slow-release composition and bioactive technology, applied in cosmetics, preparations for skin care, medical preparations containing active ingredients, etc., can solve the problems of inability to fully exert the efficacy of astaxanthin, decomposing inactivation, skin irritation, etc., Achieve the effect of promoting sustained release, improving whitening, and plumping cell shape

Inactive Publication Date: 2019-12-13
上海科颜生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, because astaxanthin contains unsaturated bonds, it may decompose and lose its activity, and when using high-concentration astaxanthin, if high-concentration astaxanthin directly contacts the skin, it may cause skin irritation or even allergies, and if you use When the concentration of astaxanthin is low, the effect of astaxanthin cannot be fully exerted

Method used

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  • Bioactive sustained-release composition
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  • Bioactive sustained-release composition

Examples

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preparation example Construction

[0047] The preparation method of the bioactive slow-release composition of the present invention comprises the following steps:

[0048] The raw materials of the bioactive sustained-release composition of the present invention are mixed and stirred evenly to obtain the bioactive sustained-release composition.

[0049] The second aspect of the present invention provides an application of the bioactive sustained-release composition, which can be applied in skin care products.

[0050] In one embodiment, the skin care products of the present invention include lotion, lotion, face cream, eye cream, mask, BB cream, essence, sunscreen, sunscreen lotion, acne lotion, acne lotion, essential oil, moisturizing water, toner , Astringent water, softening water.

[0051] The emulsion and face cream of the present invention are liquid cream cosmetics. The facial mask of the present invention is a carrier of beauty care products, including but not limited to mud cream type, tear type, jell...

Embodiment 1

[0057] Embodiment 1 of the present invention provides a bioactive sustained-release composition, the raw materials of the bioactive sustained-release composition include 5 parts of astaxanthin, 45 parts of dipalmitoylphosphatidylcholine, 8 parts of Cholesterol, 1 part stearylamine, 15 parts deionized water, 5 parts ethanol.

[0058] The astaxanthin CAS number is 472-61-7; the dipalmitoylphosphatidylcholine CAS number is 2797-68-4; the cholesterol CAS number is 57-88-5; the stearylamine CAS No. 124-30-1.

[0059] This example discloses the preparation method of the biologically active sustained-release composition, comprising the following steps:

[0060] The raw materials of the bioactive sustained-release composition of the present invention are mixed and stirred evenly to obtain the bioactive sustained-release composition.

[0061] This example provides a kind of essence, comprises described bioactive sustained-release composition, and preparation method comprises the follow...

Embodiment 2

[0064] Embodiment 2 of the present invention provides a bioactive sustained-release composition. The raw materials of the bioactive sustained-release composition include 15 parts of astaxanthin, 55 parts of dipalmitoylphosphatidylcholine, 15 parts of Cholesterol, 3 parts stearylamine, 20 parts deionized water, 15 parts ethanol.

[0065] The astaxanthin CAS number is 472-61-7; the dipalmitoylphosphatidylcholine CAS number is 2797-68-4; the cholesterol CAS number is 57-88-5; the stearylamine CAS No. 124-30-1.

[0066] This example discloses the preparation method of the bioactive sustained-release composition, and its specific implementation method is the same as that of Example 1.

[0067] This example discloses an essence, including the biologically active sustained-release composition, the specific preparation method of which is the same as that of Example 1.

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Abstract

The invention relates to a composition, and in particular, relates to a bioactive sustained-release composition. The bioactive sustained-release composition comprises the raw materials: astaxanthin, dipalmitoyl phosphatidylcholine, cholesterol, aliphatic primary amine, deionized water and ethanol. The aliphatic primary amine is alkyl primary amine of C12-C18. According to the bioactive sustained-release composition provided by the invention, the high-concentration astaxanthin is wrapped in micelles formed by dipalmitoyl phosphatidylcholine, cholesterol, aliphatic primary amine and the like, sothat the stability of the astaxanthin can be improved, and the effects of sun protection, acne removal, whitening, wrinkle resistance and aging resistance can be efficiently achieved for a long time;through the biological sustained-release composition provided by the invention, the astaxanthin is slowly released, and the problems that the high-concentration astaxanthin is in direct contact withthe skin to cause irritation to the skin and the like are prevented; in addition, by adding a certain amount of taurine salt surfactant, the slow release effect is promoted, the astaxanthin effect isfurther improved, and the astaxanthin composition can be applied to various skin care products and serves as an efficient active ingredient.

Description

technical field [0001] The present invention relates to a composition, more particularly, the present invention relates to a biologically active sustained-release composition. Background technique [0002] Astaxanthin is a terpene-like unsaturated compound, which can easily react with free radicals to scavenge free radicals and play an antioxidant role. It is the strongest antioxidant found in nature by humans so far. At the same time, astaxanthin has a strong ability to eliminate free radicals, which can prevent skin cells from being damaged by free radicals, reduce wrinkles and freckles, and is widely used as a new cosmetic raw material in creams, emulsions, lip balms, skin care products and other cosmetics. However, because astaxanthin contains unsaturated bonds, it may decompose and lose its activity, and when using high-concentration astaxanthin, if high-concentration astaxanthin directly contacts the skin, it may cause skin irritation or even allergies, and if you use...

Claims

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Application Information

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IPC IPC(8): A61K8/35A61K8/55A61K8/63A61K8/41A61K8/46A61K8/06A61Q19/00A61Q19/08A61Q19/02A61Q17/04
CPCA61K8/06A61K8/35A61K8/41A61K8/466A61K8/553A61K8/63A61K2800/522A61Q17/04A61Q19/00A61Q19/02A61Q19/08
Inventor 陈潇
Owner 上海科颜生物科技有限公司
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