Composition having whitening effect

A technology of composition and action, applied in the field of composition with whitening effect, to achieve the effect of inhibiting activity, inhibiting generation, and enhancing proliferation

Active Publication Date: 2020-01-03
ZHEJIANG WANLI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Dihydromyricetin has many unique effects such as scavenging free radicals, anti-oxidation, anti-thrombosis, anti-tumor, anti-inflammation, etc. Myricetin can improve microcirculation and anti-oxidation. At present, there is no literature report on the synergistic use of the two to improve skin conditions

Method used

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  • Composition having whitening effect
  • Composition having whitening effect
  • Composition having whitening effect

Examples

Experimental program
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Effect test

Embodiment Construction

[0025] The present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments.

[0026] The composition with whitening effect in this embodiment includes dihydromyricetin and myricetin, and the molar ratio of dihydromyricetin to myricetin is (0.01-100):1. For the convenience of consumers, the composition also includes carriers and / or excipients, which are fillers, binders, wetting agents, disintegrants, absorption promoters, surfactants, adsorption At least one of carrier, lubricant and flavoring agent. The specific types and dosages of carriers and / or excipients can be selected according to requirements.

[0027] Above-mentioned filler is selected from starch, starch, lactose, microcrystalline cellulose. The binder is selected from cellulose derivatives, alginates, gelatin, polyvinylpyrrolidone. The disintegrating agent is selected from sodium carboxymethyl starch, hydroxypropyl cellulose, cross-linked carboxymethyl ce...

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PUM

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Abstract

The invention relates to a composition having a whitening effect. The composition having a whitening effect is characterized by comprising dihydromyricetin and myricetrin, wherein the molar ratio of the dihydromyricetin to the myricetrin is (0.01-100):1. The dihydromyricetin and the myricetrin are in cooperative usage, the dihydromyricetin can significantly strengthen the proliferation effect of the myricetrin on melanoma cells B16F10 and restrain the activity of the tyrosinase so as to restrain the generation of melanin and achieve the whitening effect.

Description

technical field [0001] The present invention relates to a composition with whitening effect. Background technique [0002] Influenced by the traditional beauty concept of "one white covers three ugliness", women have a persistent pursuit of whitening. Melanin is a protein that exists in the basal layer of everyone's skin. Ultraviolet radiation will change melanin and produce a substance that protects the skin. Then melanin moves through the layers of cell metabolism to the epidermis of the skin, forming the skin we see. Skin problems such as dark spots and uneven skin tone. In order to combat the above-mentioned skin problems caused by melanin, whitening has thus become a very important daily care project. However, there are many kinds of whitening drugs or cosmetics in the prior art, and their mechanisms of action are also different. [0003] Dihydromyricetin (3,5,7,3'4'5'-hexahydroxy-2,3-dihydroflavonol, DMY) is also known as dihydromyricetin, fukien tea, white porin, sn...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/352A61K31/7048A61P17/00A61K8/49A61Q19/02C07D311/32C07D311/40C07H17/07C07H1/08
CPCA61K31/352A61K31/7048A61P17/00A61K8/498A61Q19/02C07D311/32C07D311/40C07H17/07C07H1/08A61K2800/782A61K2800/5922A61K2300/00
Inventor 陈秋平林心健沈健戚向阳
Owner ZHEJIANG WANLI UNIV
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