Scald spray and preparation method thereof

A spray and solvent technology, applied in the field of scald spray, can solve the problems of poor treatment effect of severe burns, and achieve hemostasis, pain relief, healing, obvious effect, and strong antibacterial effect

Inactive Publication Date: 2020-02-14
江西佰康药业有限责任公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] People can adopt various scald medicines to carry out the treatment of scald, but existing scald medicines are not good for the treatment of severe burns

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A scald spray, comprising the following raw materials: 0.5 kg of comfrey extract, 0.5 kg of scutellaria baicalensis extract, 0.5 kg of burnet extract, 0.5 kg of rhubarb extract, 0.15 kg of angelica extract, 0.5 kg of seaweed extract, chloroacetic acid chloride 0.03 kg of hexidine and 100 kg of solvent. The solvent includes purified water and edible alcohol, and the mass ratio of purified water to edible alcohol is 18:1.

[0038] Comfrey extract is obtained from comfrey through decoction, percolation, reflux, distillation, precipitation, standing, filtration, concentration and drying. Comfrey extract is insoluble in water but soluble in alcohol. Comfrey extract can be added to Dissolve in alcohol and mix with other liquids.

[0039]Scutellaria baicalensis extract is Scutellaria baicalensis added with water 8 times its weight and extracted for 1.5 hours, filtered to obtain the first extract and the first filter residue, adding water 6 times its weight to the first filter...

Embodiment 2

[0045] A scald spray, comprising the following raw materials: 1.3 kg of comfrey extract, 1.15 kg of baicalin extract, 1.62 kg of Burnet extract, 1.08 kg of rhubarb extract, 0.22 kg of angelica extract, 0.79 kg of seaweed extract, chlorine acetate 0.37 kg of hexidine and 100 kg of solvent.

[0046] The Burnet extract is obtained by crushing, extracting, concentrating, purifying and drying processes.

[0047] Angelica sinensis extract is obtained by elutriating and drying, pulverizing, extracting, concentrating, precipitating, extracting, crystallizing, adsorbing, analyzing and drying processes of Angelica sinensis.

[0048] The preparation method of described scald spray, concrete steps are as follows:

[0049] Step 1: Slowly add the seaweed extract into the solvent according to the ratio and stir evenly. Stir for 18 minutes to slowly dissolve the seaweed extract in the solvent to obtain the first mixture. The solvent is generally at room temperature and cannot exceed 40°C. Ot...

Embodiment 3

[0053] A scald spray, comprising the following raw materials: 1.96 kg of comfrey extract, 2.06 kg of scutellaria baicalensis extract, 1.9 kg of Burnet extract, 2.17 kg of rhubarb extract, 0.29 kg of angelica extract, 1.15 kg of seaweed extract, chlorine acetate 0.69 kg of hexidine and 100 kg of solvent.

[0054] The rhubarb extract is obtained by decocting, percolating, refluxing, distilling, precipitating, standing, filtering, concentrating and drying the rhubarb.

[0055] The seaweed extract is seaweed, which is dissolved in water at constant temperature and filtered to obtain the filtrate. The filtrate is concentrated to a relative density of 1.20 at 60°C, and 4 times its weight of ethanol solution with a mass fraction of 95% is added to it for alcohol precipitation and suction filtration. , and then washed with absolute ethanol, acetone, ether for several times, then dried under reduced pressure and purified by gel column chromatography.

[0056] The preparation method of...

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PUM

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Abstract

The invention discloses a scald spray and a preparation method thereof, which aim to solve the problem of poor effect of an existing scald medicine. The scald spray comprises the following raw materials in parts by weight: 0.5 to 2.5 parts of a radix lithospermi extract, 0.5 to 2.5 parts of a radix scutellariae extract, 0.5 to 2.5 parts of a radix sanguisorbae extract, 0.5 to 2.5 parts of a radixet rhizoma rhei extract, 0.15 to 0.35 part of a radix angelicae sinensis extract, 0.5 to 1.5 parts of a seaweed extract, 0.03 to 0.90 part of chlorhexidine acetate and 100 parts of a solvent. The traditional Chinese medicine composition is reasonable in formula, has the effects of sealing, resisting bacteria, resisting inflammation, stopping bleeding, relieving pain and promoting healing of scalded wounds, is high in pain relieving speed, greatly relieves the pain of a patient, is convenient to use, has an obvious effect of treating scalds, does not need skin grafting when being used for treating three-degree burns, and is close to scar-free healing.

Description

technical field [0001] The invention relates to the field of scalds, in particular to a scald spray. Background technique [0002] Scalds are also very common in life or war. Normal fire, hot liquid (boiling water), etc., hot gas or solid and electric burn contact receptors, occasionally caused by laser or acid-base. There are more than ten million patients with burns and scalds every year in my country, and hundreds of thousands of them need to be hospitalized. The death rate of severe and extremely severe burns is as high as about 18, and many patients lose their ability to work and live because of this. According to statistics, every year, 950,000 disabled patients with burns in various degrees will be added to the society due to burns and scalds. After wound healing, many patients with burns and scalds will leave different degrees of scars due to the poor effect of topical medication on the wound surface, resulting in dysfunction, even disfigurement or permanent disabi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/739A61K9/12A61K47/10A61P17/02A61K31/155
CPCA61K9/0014A61K9/12A61K31/155A61K36/02A61K36/232A61K36/30A61K36/539A61K36/708A61K36/739A61K47/10A61P17/02A61K2300/00
Inventor 汪昆
Owner 江西佰康药业有限责任公司
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