High-connectivity gradient bionic artificial bone structure and preparation method thereof

An artificial bone and gradient technology, applied in bone implants, medical science, prostheses, etc., can solve the problem of unconsidered bone gradient structure, reduce the elastic modulus of implants, etc. Effects of bone ingrowth, bonding strength, and interfacial shear strength improvement

Inactive Publication Date: 2020-04-10
JILIN UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In summary, artificial bone implants have been relatively mature in clinical application, and the design process is simple. The method of artificial bone design with metal dense models has been widely used, and simple cell and truss structure arrays are grad

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  • High-connectivity gradient bionic artificial bone structure and preparation method thereof
  • High-connectivity gradient bionic artificial bone structure and preparation method thereof
  • High-connectivity gradient bionic artificial bone structure and preparation method thereof

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Embodiment Construction

[0025] The detailed content of the present invention and its specific implementation will be further described below in conjunction with the accompanying drawings.

[0026] see Figure 1 to Figure 3 As shown, the high-connectivity gradient bionic artificial bone topology of the present invention, on the basis of revealing the mechanism of joint interface wear and fatigue failure, proceeds from the principle and method of realizing toughening, drag reduction, wear resistance, and material exchange to promote bone ingrowth. The principle of bionics studies scientific issues such as the multi-factor coupling effect of internal bone structure and materials and the construction of artificial bone gradient mechanical properties, and provides a reliable structure for improving the service performance of artificial bones. This method faces the urgent demand for high-performance artificial bones in the interdisciplinary fields of biomedical engineering and machinery. The internal struc...

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Abstract

The invention relates to a high-connectivity gradient bionic artificial bone structure and a preparation method thereof, belonging to the field of medical artificial bones. The method is suitable forthe design of a gradient bionic artificial bone with three-period pores, and a plurality of holes which are communicated with one another are distributed completely or locally in the artificial bone;each of the pores has three dimensions periodically extending towards three peripheral axes, and pore sizes can be controlled through porosity; the porosity can reduce the elasticity modulus of a metal material, and avoid interfacial loosening, stress shielding and degradation or absorption of bone tissue caused by too high elasticity modulus of metal and the like. The artificial bone is printed and constructed layer by layer by using metal powder or a hydroxyapatite biological material in additive manufacturing; and holes in the surface of the artificial bone can promote interface osteogenesis, enhance interface fusion and induce osteogenic differentiation of backbone cells at an interface, and bone tissue and an artificial bone implant are combined more firmly.

Description

technical field [0001] The invention relates to the field of medical artificial bones, in particular to a highly connected gradient bionic artificial bone structure consistent with the modulus of human autologous bone and a preparation method thereof. Background technique [0002] About 400 million people around the world suffer from joint diseases. Every year, bone defects caused by external forces such as traffic accidents lead to more than 2 million bone replacement operations (data source: World Health Organization). Although autologous bone grafting and allogeneic bone grafting are effective methods for repairing bone defects, problems such as pain, infection, and immune rejection may occur, so artificial bone scaffolds have been developed rapidly. [0003] The stress conditions of artificial bone serving in the human body and the microenvironment of the organism are complex and changeable. The system composed of artificial bone and bone is at the material interface, an...

Claims

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Application Information

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IPC IPC(8): A61F2/28A61F2/30A61F2/46
CPCA61F2/28A61F2/30942A61F2/4644A61F2/4657A61F2002/2835A61F2002/30199A61F2002/30784A61F2002/3093A61F2002/30943A61F2002/4666
Inventor 马志超刘东妮佟帅
Owner JILIN UNIV
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