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Papaya ferment composition for improving and promoting functions of digestion and absorption system, preparation method thereof and composite nano preparation

An absorption system, the technology of papaya enzyme, is applied in the field of medical and health food to achieve the effects of reducing atherosclerosis, promoting metabolism, reducing inflammation and absorbing cell debris

Pending Publication Date: 2020-06-23
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

On this basis, the inhibitory effect of a form of tungsten element (nano-tungsten ions) on Enterobacteriaceae in the intestinal bacterial environment was analyzed and empirically studied, so as to screen and determine a method for restoring and maintaining normal digestion. Papaya fruit enzyme compound nano preparation with absorption function, thus solving the defects of existing practical application products

Method used

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  • Papaya ferment composition for improving and promoting functions of digestion and absorption system, preparation method thereof and composite nano preparation
  • Papaya ferment composition for improving and promoting functions of digestion and absorption system, preparation method thereof and composite nano preparation
  • Papaya ferment composition for improving and promoting functions of digestion and absorption system, preparation method thereof and composite nano preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Formula (percentage by weight):

[0041] Ingredients:

[0042] Papain 15%;

[0043] Amylase 2%;

[0044] Bromelain 2%;

[0045] Papain 1%;

[0046] Nano tungsten ion: 0.4%;

[0047] Accessories:

[0048] Calcium Carbonate 18%;

[0049] Sucrose 50%;

[0050] Cereal starch 8%;

[0051] Papaya spice 1%;

[0052] Vegetable stearic acid 2%;

[0053] Vegetable Magnesium Stearate 0.6%.

[0054] The preparation method comprises the following steps:

[0055] 1) Preparation of main material nanocrystals:

[0056] Media grinding method: Weigh the surfactant SDS with a concentration of 5wt% and place it in a 100mL grinding tank, add 15mL of distilled water and then sonicate for 2min; weigh various enzymes and papaya enzymes according to the stated amount, mix them and place them as raw materials Ultrasonic several minutes in above-mentioned grinding pot, after the drug is fully dispersed, add 30g of zirconia (ZrO 2 ) Grinding beads; install the machine, adjust the mac...

Embodiment 2

[0063] Embodiment 2 performance test

[0064] 1) Observation of nano-tablet morphology and particle size: the particle size and particle size distribution were measured by a dynamic light scattering nanometer particle size analyzer (PSSNicomp380, USA) (Table 1).

[0065] Table 1. Particle size distribution of ingredients in nanotablets (Dynamic Light Scattering Nanoparticle Size Analyzer)

[0066] type D10 D50 D90 Nano tablet 21.14 48.32 81.54 Nano tungsten ion 1.30 5.89 16.01 Modified calcium carbonate 1.01 4.56 19.61

[0067] The test results show that the prepared nano-crystals have a particle size of about 100nm and a rod-like or needle-like crystal structure; while the size of the nano-preparation is reduced, the performance and stability of the product are significantly improved.

[0068] 2) Determination of encapsulation efficiency and drug loading of the nano-tablet prepared in Example 1: Determination of the weight percentage o...

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Abstract

The invention relates to a papaya ferment composition for improving and promoting functions of a digestion and absorption system, a preparation method thereof and a composite nano preparation, and belongs to the field of medical health-care food. The papaya enzyme composition for improving and promoting the functions of the digestion and absorption system comprises the following components in percentage by weight: main materials comprising 10-20% of papain, 1-5% of amylase, 1-5% of bromelain, 0.5-2% of a papaya enzyme and 0.1-1% of nano tungsten ions; and auxiliary materials comprising 10-25%of calcium carbonate, 30-70% of sucrose, 5-12% of cereal starch, 0.05-0.2% of papaya spice, 1-4% of plant stearic acid and 0.4-2% of plant magnesium stearate. The papaya enzyme composition accords with composition of digestive enzymes existing in the body of Chinese people, and can promote digestion and absorption of various nutrient substances. The ratio of the enzyme components of the papaya ferment composition is designed according to characteristics of various dietary structures of Chinese people, so that various dietary digestion problems are met. The papaya fruit enzyme product can properly supplement auto-eliminating enzymes, catalyze the original digestive enzymes of an organism to the maximum extent, and improve functions of the enzymes.

Description

technical field [0001] The invention relates to the field of medical and health food, and furthermore, relates to a papaya enzyme composition for improving and promoting the function of the digestive and absorption system, a preparation method and a composite nano-preparation. Background technique [0002] With the continuous development of science and technology and the continuous progress of human society, life health and quality of life have been continuously improved. But while people's lives are getting richer, people's bodies are also getting richer. Obesity has become a new type of disease that is eroding health, followed by a variety of diseases. There are two main reasons for this: one is that people’s dietary structure has changed, and excessive intake of high-protein, high-fat and other high-energy foods leads to metabolic disorders in the human body and imbalances in the secretion of various enzymes in the body; on the other hand, environmental factors Changes i...

Claims

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Application Information

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IPC IPC(8): A23L29/00A23L33/10A23L33/16
CPCA23L33/10A23L29/06A23L33/16A23V2002/00A23V2200/30A23V2200/326A23V2200/324
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