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Bozhou moutan cortex traditional Chinese medicine preparation and preparation method thereof

A traditional Chinese medicine preparation, the technology of Bo paeonol, which is applied in the direction of medical formula, non-central analgesics, antipyretics, etc., can solve the problems of low paeonol content and purity, low effective rate, and insufficient curative effect, and achieve Significant curative effect, high purity and high content

Inactive Publication Date: 2020-07-10
亳州言合医药科技服务有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing traditional Chinese medicine preparations containing paeonol active ingredients have the following technical problems: 1) the content and purity of the anti-inflammatory and analgesic component paeonol are low, and the curative effect on pain symptoms such as muscle pain, visceral pain, rheumatism pain, and neuralgia is not significant enough, Efficiency is not high; 2) supporting distillation equipment can't obtain the high paeonol distillate of active ingredient content, has reduced the curative effect and the safety of Chinese medicine preparation finished product

Method used

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  • Bozhou moutan cortex traditional Chinese medicine preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] refer to figure 1 As shown, a kind of Bo paeonol traditional Chinese medicine preparation of the present embodiment is prepared from the following raw materials in parts by weight: 52 parts of Bo paeonol, 19 parts of Coptidis rhizome, 16 parts of Scutellaria baicalensis, 10 parts of honeysuckle, 9 parts of Cimicifuga, 5 parts of licorice share.

[0032] The preparation method of this Bodan cortex traditional Chinese medicine preparation comprises the following steps:

[0033] S1, preparation of Bo paeonol extract: Take Bo paeonol by weighing, add in the first-stage distillation tank 1 of multistage distillation equipment, add 7 times of weight purified water from feed pipe 3, vacuum pump 5 draws vacuum degree through vacuum tube 4 to -0.097MPa, and the temperature rises to 63°C, the light fraction produced by the primary distillation tank 1 enters the first separation chamber 11, and after being deodorized and decolorized by the activated carbon filter 21, under the ac...

Embodiment 2

[0039] refer to figure 1 As shown, a kind of Bo paeonol traditional Chinese medicine preparation of the present embodiment is prepared from the following raw materials in parts by weight: 48 parts of Bo paeonol, 20 parts of Coptis chinensis, 15 parts of Scutellaria baicalensis, 12 parts of honeysuckle, 11 parts of Cimicifuga, 6 parts of licorice share.

[0040] The preparation method of this Bodan cortex traditional Chinese medicine preparation comprises the following steps:

[0041] S1, preparation of Bo paeonol extract: Weigh Bo paeonol, add in the first-stage distillation tank 1 of multistage distillation equipment, add purified water of 8 times the weight from feed pipe 3, and vacuum pump 5 draws vacuum through vacuum tube 4 to -0.098MPa, the temperature rises to 65°C, the light fraction produced by the primary distillation tank 1 enters the first separation chamber 11, and after being deodorized and decolorized by the activated carbon filter 21, under the action of the t...

Embodiment 3

[0047] refer to figure 1 As shown, a kind of Bo paeonol Chinese medicine preparation of the present embodiment is prepared from the following raw materials in parts by weight: 56 parts of Bo paeonol, 21 parts of Coptidis rhizome, 17 parts of Scutellaria baicalensis, 12 parts of honeysuckle, 10 parts of Cimicifuga, 4 parts of licorice share.

[0048] The preparation method of this Bodan cortex traditional Chinese medicine preparation comprises the following steps:

[0049] S1, preparation of Bo paeonol extract: take Bo paeonol by weighing, add in the first-stage distillation tank 1 of multistage distillation equipment, add 6-8 times of weight purified water from feed pipe 3, vacuum pump 5 extracts through vacuum tube 4 The vacuum degree reaches -0.096MPa, and the temperature rises to 66°C. The light fraction produced by the primary distillation tank 1 enters the first separation chamber 11, and after being deodorized and decolorized by the activated carbon filter screen 21, it...

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Abstract

The invention discloses a Bozhou moutan cortex traditional Chinese medicine preparation and a preparation method thereof. The traditional Chinese medicine preparation comprises a plurality of traditional Chinese medicine materials with the effects of clearing away heat and relieving exterior syndromes, diminishing inflammation and alleviating pain, takes Bozhou moutan cortex as a main component and also takes rhizoma coptidis, radix scutellariae, flos lonicerae, rhizoma cimicifugae and liquorice root, and the traditional Chinese medicine preparation is prepared by the steps of extraction of the Bozhou moutan cortex, extraction of other traditional Chinese medicine components, mixing of auxiliary materials, potting and sterilization. The effective ingredients in the Bozhou moutan cortex areextracted by special multi-stage distillation equipment, so that the content and purity of anti-inflammatory and analgesic ingredient paeonol are high, the traditional Chinese medicine preparation has significant effects on muscle pain, visceral pain, rheumatic pain and nerve pain through curative effect verification, clears away heat and alleviates pain, the effective rate reaches 83.3-90%, andthe traditional Chinese medicine preparation is suitable for industrial production.

Description

technical field [0001] The invention relates to the technical field of antipyretic and analgesic preparations, in particular to a traditional Chinese medicine preparation of Bodan cortex and a preparation method thereof. Background technique [0002] Bodan cortex is a local medicinal material in Bozhou. Cortex paeonol is the root bark of peony. The peony is excavated in autumn and spring for 3-5 years. After removing the skin and flesh of the root, it is in the shape of a tube or semicircle, with longitudinally cut pieces. Cracks, loose seams, or curling inwards. Generally 5-25 cm long, 0.5-1.2 cm in diameter, thicker skin, 2-5 cm in thickness. The outer surface is taupe, the inner surface is gray, with obvious fine longitudinal texture, and colorless paeonol crystals can be seen. Brittle and hard, the fracture surface is relatively flat, powdery. Traditional Chinese medicine believes that paeonol can clear away heat, purify fire, detoxify and soothe the liver. Modern me...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61P29/00A61K36/71A61K36/65A61K9/08A61K47/26
CPCA61K9/0095A61K36/355A61K36/484A61K36/539A61K36/65A61K36/71A61K36/718A61K47/26A61K2236/331A61K2236/37A61P29/00A61K2300/00
Inventor 陈志强
Owner 亳州言合医药科技服务有限公司
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