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Ginseng and spina date seed tablet compound product and preparation method thereof

A technology of jujube seed and ginseng, which is applied to medical preparations containing active ingredients, pharmaceutical formulas, peptide/protein components, etc., and can solve the problems of low purity of extracts and consumption of toxic solvents, etc.

Pending Publication Date: 2020-08-18
福建华尔康生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Extracts of ginseng, jujube seed, yizhiren, yuliren, cordyceps militaris, medlar, poria cocos, lily, platycodon, licorice and other medicinal materials, oyster peptide, spirulina platensis, rice bran fat peroxide, γ-aminobutyric acid, xylose Alcohol and other medicinal and food homologous materials contain a variety of active ingredients, but at present, solvent extraction is the main method, which consumes a lot of toxic solvents; and the purity of the extract is not high

Method used

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  • Ginseng and spina date seed tablet compound product and preparation method thereof
  • Ginseng and spina date seed tablet compound product and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1: A kind of compound product of ginseng jujube seed sheet

[0033] (1) Weigh and select 1500 grams of ginseng, 1500 grams of jujube kernels, 1000 grams of Yizhiren, 1000 grams of Yu Liren, 1000 grams of Cordyceps militaris, 1000 grams of wolfberry, 1000 grams of Poria cocos, 1000 grams of lily, 500 grams of bellflower, licorice 500 grams, then pulverized together and sieved to obtain a fineness of 20-50 mesh medicated powder;

[0034] (2) Soak the medicinal powder obtained in step (1) with drinking water for 3 hours, the ratio of solid to liquid is 1:15 (that is, 15-20kg of water per 1kg of medicinal powder), and then add 1.0% cellulase and 1.0% of the weight of the medicinal powder ATPase and 1.0% β-glucosidase, adjust the pH to 6.0-6.5 with 1mol / L hydrochloric acid solution, and enzymolyze at 45-55°C for 180min; Enzyme treatment for 5 minutes to obtain an enzymatic solution; the activity of the cellulase used is 20000U / g, the activity of ATPase is 30000U / ...

Embodiment 2

[0040] Embodiment 2: A kind of compound product of ginseng jujube seed sheet

[0041] (1) Weigh and select 3000 grams of ginseng, 3000 grams of jujube kernels, 2000 grams of Yizhiren, 2000 grams of Yu Liren, 2000 grams of Cordyceps militaris, 2000 grams of medlar, 2000 grams of Poria cocos, 2000 grams of lily, 1000 grams of bellflower, licorice 1000 grams, then pulverized together, and sieved to obtain a medicated powder with a fineness of 20-50 mesh;

[0042] (2) Soak the medicinal powder obtained in step (1) with drinking water for 3 hours, the ratio of solid to liquid is 1:15 (that is, 15-20kg of water per 1kg of medicinal powder), and then add 1.0% cellulase and 1.0% of the weight of the medicinal powder ATPase and 1.0% β-glucosidase, adjust the pH to 6.0-6.5 with 1mol / L hydrochloric acid solution, and enzymolyze at 45-55°C for 180min; Enzyme treatment for 6 minutes to obtain an enzymatic solution; the activity of the cellulase used is 20000U / g, the activity of ATPase is ...

Embodiment 3

[0048] Embodiment 3: A kind of compound product of ginseng jujube seed sheet

[0049] (1) Weigh and select 4500 grams of ginseng, 4500 grams of wild jujube kernels, 3000 grams of Yizhiren, 3000 grams of Yu Liren, 3000 grams of Cordyceps militaris, 3000 grams of medlar, 3000 grams of Poria cocos, 3000 grams of lily, 1500 grams of bellflower, licorice 1500 grams, then pulverized together, sieved to obtain a fineness of 20-50 mesh medicated powder;

[0050] (2) Soak the medicinal powder obtained in step (1) with drinking water for 3 hours, the ratio of solid to liquid is 1:15 (that is, 15-20kg of water per 1kg of medicinal powder), and then add 1.0% cellulase and 1.0% of the weight of the medicinal powder ATPase and 1.0% β-glucosidase, adjust the pH to 6.0-6.5 with 1mol / L hydrochloric acid solution, and enzymolyze at 45-55°C for 180min; Enzyme treatment for 7 minutes to obtain an enzymatic solution; the activity of the cellulase used is 20000U / g, the activity of ATPase is 30000U...

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PUM

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Abstract

The invention discloses a ginseng and spina date seed tablet compound product and a preparation method thereof. The preparation method comprises the steps: crushing ginseng, spina date seeds, fructusalpiniae oxyphyllae, bunge cherry seeds, cordyceps militaris, fructus lycii, poria cocos, lily, platycodon grandiflorum and liquorice, hydrolyzing and carrying out enzymolysis; carrying out a series of production processes such as CO2 supercritical extraction, membrane filtration, concentration, spray drying, powder preparation and the like to prepare extract dry powder, and then compounding the extract dry powder with oyster peptide, spirulina platensis, rice bran fatty alcohol, gamma-aminobutyric acid and xylitol to prepare tablets. The product is rich in active substances, scientific in formula, safe and free of toxic and side effects, and the method has the advantages of being high in extraction yield, high in extraction speed, nonflammable, advanced in preparation process, free of environmental pollution and the like, and is an efficient, environment-friendly and low-cost biotechnological preparation method for extracting active substances from the Chinese herbal medicines.

Description

technical field [0001] The invention relates to a compound Chinese herbal medicine product and a preparation method thereof, in particular to a compound product containing ginseng, jujube seed, yizhiren, yuliren, cordyceps militaris, medlar, tuckahoe, lily, bellflower, licorice, oyster peptide, spirulina platensis , rice bran fat wanalcohol, γ-aminobutyric acid, xylitol and other medicinal and food homologous raw materials, compound preparations made by bioengineering technology. Background technique [0002] Since the beginning of the 21st century, human beings have paid more attention to health, and the research and development of natural medicinal plant products with Chinese characteristics has far-reaching significance to human health. Extracts of ginseng, jujube seed, yizhiren, yuliren, cordyceps militaris, medlar, poria cocos, lily, bellflower, licorice and other medicinal materials, oyster peptide, spirulina platensis, rice bran fat peroxide, γ-aminobutyric acid, xylo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/01A61P25/20A61K36/9062A61K31/045A61K31/197A61K35/748
CPCA61K36/258A61K36/725A61K36/9062A61K36/736A61K36/068A61K36/815A61K36/076A61K36/8967A61K36/346A61K36/484A61K38/012A61K35/748A61K31/045A61K31/197A61P25/20A61K2300/00
Inventor 郭震宇郭耀荣阮庭泉罗诚江辉
Owner 福建华尔康生物科技有限公司
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