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Anti-wrinkle composition as well as preparation method and application thereof

A technology of composition and extract, which is applied in the field of anti-wrinkle composition and its preparation, can solve the problems of single function and limited anti-wrinkle effect, and achieve the effect of high bioavailability, reduction of degradation, and lightening of skin fine lines

Active Publication Date: 2020-09-08
泉后(广州)生物科技研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is to overcome the defects and deficiencies of the existing anti-wrinkle products with single function and limited anti-wrinkle effect, and provide an anti-wrinkle composition based on the mechanism of wrinkle formation and aging performance, and improve the anti-wrinkle effect from various aspects

Method used

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  • Anti-wrinkle composition as well as preparation method and application thereof
  • Anti-wrinkle composition as well as preparation method and application thereof
  • Anti-wrinkle composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～3

[0040] Examples 1~3 An anti-wrinkle lotion

[0041] See Table 1 for the components of the anti-wrinkle lotion.

[0042] Table 1 Examples 1-3 Anti-wrinkle lotion raw materials

[0043]

[0044]

[0045] Preparation:

[0046] S1. Put the component A raw materials in an emulsifying pot, heat to 85°C, dissolve and disperse, homogenize at 2500rpm for 3min, vacuum defoam, stir at 15rpm and cool down to 45°C to obtain mixture X;

[0047] S2. The raw material of component B is made into an aqueous solution and added to the mixture X obtained in step S1, homogenized at 2500 rpm for 2 minutes, and stirred at 15 rpm to obtain a mixture Y, and the temperature during the preparation process is maintained at 45°C;

[0048] S3. Add the component C raw materials to the mixture Y obtained in step S2, homogenize at 2500 rpm for 2 minutes, maintain the temperature at 45°C during the preparation process, stir and cool to 30°C at 15 rpm, and discharge.

experiment example 1

[0056] Experimental Example 1 Evaluation of anti-wrinkle efficacy

[0057] Instrument: Visia-CR (Canfield); Image-Pro skin comprehensive analysis software (MediaCybernetics).

[0058] Samples: The lotions of Examples 1 to 3 and Comparative Examples 1 to 5, totally 8 types.

[0059] Subject's choice

[0060] Qualified volunteers were selected and signed an informed consent form to ensure that 80 people were finally completed, 10 volunteers for each sample trial.

[0061] Selection criteria: Healthy female volunteers with daily skin care products habit, Chinese, 35 to 45 years old; volunteers have fine lines / wrinkles around the eyes on their faces and are not sensitive to commonly used cosmetics; subjects have high compliance.

[0062] Exclusion criteria: people who have used antihistamines in the past week or immunosuppressants in the past month; people who have used any anti-inflammatory drugs at the test site in the past two months; patients with insulin-dependent diabetes; patients wit...

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Abstract

The invention belongs to the technical field of cosmetics, and particularly relates to an anti-wrinkle composition as well as a preparation method and application thereof. The composition is mainly prepared from acetylated sodium hyaluronate, euglena gracilis polysaccharide, a green alga extract, milk protein, hydrolyzed collagen, acetyl hexapeptide-8 and the like, all the components have a synergistic effect, collagen hydrolase can be inhibited, and degradation of collagen is reduced; a fine film is formed, the skin structure is improved, and the skin is tightened; and contraction and the like of muscle cells are reduced, and the anti-wrinkle effect is improved from multiple aspects.

Description

Technical field [0001] The invention belongs to the technical field of cosmetics. More specifically, it relates to an anti-wrinkle composition and its preparation method and application. Background technique [0002] The skin is an important organ with various physiological functions such as protecting the human body from the external environment, preventing internal moisture and useful components from flowing out, regulating body temperature or excretion. Wrinkles are one of the signs of skin aging. The human body is affected by endogenous or exogenous factors, resulting in changes in skin supporting tissues and skin structure, resulting in loss of skin water retention capacity, and changes in the order of elastic fibers and collagen. , Resulting in a decrease in the mechanical force and elasticity of the skin, forming depressions, and eventually wrinkles. There are many factors that cause wrinkles, such as reactive oxygen species, ultraviolet radiation, free radicals, inflamm...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9722A61K8/63A61K8/64A61K8/65A61K8/73A61K8/9706A61K8/19A61Q19/08A61Q19/00
CPCA61K8/735A61K8/73A61K8/9722A61K8/64A61K8/65A61K8/19A61K8/63A61K8/9706A61Q19/005A61Q19/08A61K2800/5922A61K2800/782
Inventor 林吉珊
Owner 泉后(广州)生物科技研究院有限公司
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