Preparation method of PAM/PVP/PAA triple-network hydrogel

Abstract

The invention relates to a preparation method of PAM / PVP / PAA triple-network hydrogel. The triple-network hydrogel is a cross-linked polymer interpenetrating network formed by three polymers, and the mechanical properties of gel are greatly enhanced. The preparation method of the hydrogel specifically comprises the following steps: 1) dissolving acrylamide (AM), acrylic acid (AA), ferric chloride hexahydrate and polyvinylpyrrolidone (PVP) in water in proportion, and carrying out uniform mixing; 2) sequentially adding a cross-linking agent and an initiator, carrying out argon oxygen displacementtreatment, and then adding an initiator and an accelerator, and 3) carrying out ultrasonic treatment on the obtained mixed solution, conducting reacting at 40 DEG C for 1 hour, and finally performingstanding at room temperature for 24 hours. The prepared triple-network composite hydrogel has high mechanical strength, good self-repairing performance and certain conductivity, the preparation process is simple, the raw materials are green, non-toxic and harmless, and the triple-network composite hydrogel can be applied to the aspects of medical instruments, bionic electronic skin, injectable hydrogel and the like.

Description

technical field

[0001] The invention belongs to the field of hydrogel preparation, and in particular relates to a preparation method of PAM / PVP / PAA triple network hydrogel. Background technique

[0002] Hydrogel is a functional polymer material with a three-dimensional network structure formed by cross-linking through chemical bonds or physical interactions. The polymer network contains a large amount of water and is soft to the touch and can maintain a certain shape. Due to their physicochemical properties, hydrogels have been widely used in the fields of cartilage substitutes, medical devices, and flexible electronics, but the further application of hydrogels is still limited by their poor mechanical properties. When traditional hydrogels are subjected to mechanical loads, local stress concentration will inevitably occur. The accumulation of local stress will cause the mesh to break, and network defects will be generated through the expansion of cracks, which will eventual...