255 results about "Injectable hydrogels" patented technology

The invention relates to the technical field of material physical property detection, and discloses an injectable hydrogel wound dressing water absorbability detection method, which comprises: constructing a main measurement and reference dual channel, and synchronously monitoring a mixed conductivity signal and an interference signal generated only by gel self ion leakage; according to the method, the interference is deducted through real-time differential operation, a pure target signal is obtained, and then the water absorption volume of the hydrogel is calculated through inversion based on the law of conservation of mass, a measured object is transferred to an external solution from a gel body, and the interference of a sample is stripped through an endogenous dynamic correction mechanism, so that the accuracy of the water absorption volume of the hydrogel is improved. The determinacy of a measurement result is derived from a physical law instead of model hypothesis, so that double restrictions caused by irregular sample forms and complexity of a chemical environment are avoided, and reliable quantification of the water absorption performance of the in-situ dynamic forming hydrogel is realized.

The invention discloses injectable hydrogel with redox activity and electroactivity as well as a preparation method and application of the injectable hydrogel, and belongs to the technical field of medical materials. The preparation method comprises the following steps: reacting methacrylic anhydride and polysaccharide molecules in a solvent to prepare a double-bond functional polymer; the preparation method comprises the following steps: firstly, pre-polymerizing dopamine in a solvent, and then adding MOF (Metal Organic Framework) to carry out polymerization reaction, so as to prepare dopamine modified MOF; reacting the dopamine modified MOF, EDOT and ferric salt in a solvent, and collecting the precipitate to prepare a nano filler; the preparation method comprises the following steps: jointly dispersing the double-bond functional polymer, active polypeptide, a photoinitiator and nano filler into a solvent, and carrying out photocuring cross-linking. The preparation condition is mild, gel forming is rapid, the method is simple, the prepared hydrogel has injectable performance and conductive performance, catalytic activity of natural enzyme can be simulated, active oxygen removal can be achieved in the early stage of myocardial ischemia, electrical conduction of infarction parts can be enhanced, and effective recovery of cardiac functions can be achieved.

The invention relates to the technical field of material physical property testing, and discloses an injectable hydrogel wound dressing tensile strength testing method, which comprises: establishing a correlation model of the mass and the maximum fracture load of a standard sample at different temperatures, and the correlation model of the initial rigidity and the temperature; measuring the mass and the actual maximum fracture load of the to-be-measured sample, and determining the actual initial rigidity of the to-be-measured sample; according to the method, the actual initial stiffness is calculated, the equivalent temperature of the test is converted by utilizing the actual initial stiffness, the standard theoretical maximum fracture load is calculated in combination with the sample mass and the corresponding model, and the performance is judged by comparing the two, so that the measurement of the geometric dimension of an irregular sample is avoided by constructing the correlation between the mass and the mechanical performance; the quality control problem of an in-situ forming material is solved, and the reliability of a judgment result in an industrial environment is further ensured by utilizing mechanical response data of the same test through an integrated temperature self-adaptive calibration mechanism.

The invention provides dual-response antibacterial repair-promoting injectable hydrogel as well as a preparation method and application thereof, and belongs to the technical field of biomedical materials. Two-dimensional titanium carbide (TiO2 (at) MXene) with the surface modified with titanium dioxide and a bioactive substance are introduced into a hydrogel matrix to serve as functional additives, TiO2 (at) MXene is a photo-thermal and ultrasonic response material, can emit heat under 808 nm near-infrared (NIR) light irradiation and low-intensity pulsed ultrasound (LIPUS) stimulation, and can generate reactive oxygen species (ROS) for sterilization under LIPUS stimulation; when the temperature of the hydrogel is increased, the bioactive substances can be slowly released from the hydrogel, and cell proliferation and tissue repair are promoted. The hydrogel provided by the invention can be coated on the surface of skin or injected under soft tissue, so that the functions of resisting bacteria in the early stage of inflammation and promoting tissue repair in the later stage are realized.

The invention discloses injectable hydrogel for photo-thermal adjuvant therapy of periodontitis and a preparation method, and belongs to the technical field of high polymer material preparation, the preparation method comprises the following steps: reacting MXene dispersion liquid with epigallocatechin gallate and MgSO4; then sequentially carrying out ultrasonic treatment, centrifugation, washing and freeze-drying to obtain a multifunctional nanosheet MP-Mg; adding the multifunctional nanosheet MP-Mg into an oxidized gellan gum aqueous solution, and carrying out a mixed reaction to obtain a solution A; mixing the quaternary ammonium salt chitosan aqueous solution and the carboxymethyl chitosan aqueous solution in equal volume, and reacting to obtain a solution B; and mixing the solution A and the solution B in equal volume for reaction. The hydrogel prepared by the preparation method disclosed by the invention has injectability, photo-thermal responsiveness, biological membrane penetrability, synergistic antibacterial property and long-acting anti-inflammatory property, and an innovative and practical photo-thermal adjuvant therapy platform is provided for clinical treatment of periodontitis.

The invention belongs to the technical field of biomedical anti-inflammatory gels, and discloses a renewable boundary lubrication natural polyphenol anti-inflammatory hydrogel and a preparation method and application thereof.The hydrogel is of a hydrophilic viscoelastic sea island structure, gallic acid grafted gelatin blended with hyaluronic acid serves as a base material, celecoxib lipidosome is entrapped in the hydrogel, and the hydrogel is prepared from natural polyphenols, an articular cavity is injected through an enzyme crosslinking technology to form gel, hyaluronic acid and lipidosome form a hydrated lubricating layer on a cartilage-gel interface, and after the interface is abraded, internal lipidosome and hyaluronic acid are exposed to supplement lubrication so as to form sustainable lubrication; the liposome responds to friction shear crushing to release celecoxib and cooperates with gallic acid at an interface to resist inflammation progress and repair cartilage, the injectable hydrogel is developed based on gallic acid, hyaluronic acid, gelatin and celecoxib liposome to treat early osteoarthritis, mechanical lubrication and inflammation resistance are combined, and the preparation method has the advantages that the preparation method is simple, the preparation cost is low, and the application prospect is wide. The problems of large-dose toxicity, short lubrication period and the like caused by independent treatment are effectively solved, and the preparation has important clinical application significance.

The present invention relates to the field of medical biomaterial technology, and particularly, to an in-situ formed injectable hydrogel material and use thereof in preparing a tissue repair formulation. The in-situ formed injectable hydrogel material of the present invention comprises two fluid components: component A and component B, wherein component A is an activated linker solution, and component B is a collagen and / or gelatin fluid. The hydrogel material of the present invention is prepared during use. First, a cross-linking activator is used to activate the linker to give component A. During this process, a portion of the cross-linking activator is consumed, thus reducing the amount of cross-linking activator in contact with tissues. Subsequently, component A and component B are mixed, and the macromolecules in the components undergo chemical cross-linking to form a gel. A neutralizing agent is introduced into component B to consume the cross-linking activator in the material during the chemical cross-linking of the macromolecules and a period thereafter, so as to further reduce the residual amount of cross-linking activator in contact with tissues and enhance the biocompatibility of the hydrogel material.

The invention relates to antibacterial hydrogel, in particular to injectable hydrogel which is antioxidant, responds to hydrogen peroxide and glucose and is antibacterial, a preparation method of the injectable hydrogel and application of the injectable hydrogel to preparation of antibacterial hydrogel dressing for repairing diabetic infectious wounds. The injectable hydrogel capable of resisting oxidation, responding to hydrogen peroxide and glucose and resisting bacteria has a porous three-dimensional network structure and mainly comprises gelatin modified by 4-carboxyphenylboronic acid, tannic acid, zinc chloride and water. The porous three-dimensional network structure is obtained by chemical crosslinking of gelatin modified by 4-carboxyphenylboronic acid and tannic acid, and zinc chloride is loaded in the hydrogel by complexing with the tannic acid. The hydrogel disclosed by the invention has good self-healing ability, injectable ability, oxidation resistance, hydrogen peroxide and glucose response property, good biocompatibility and excellent antibacterial property.

The invention relates to the field of nano drug delivery systems, in particular to composite hydrogel targeting macrophage mitochondria as well as a preparation method and application of the composite hydrogel. The ROS response type liposome composite injectable hydrogel targeting the macrophage mitochondria is prepared by compounding the cationic liposome and the hydrogel, can be used as a nano drug delivery system suitable for oral local drug delivery, has good biocompatibility, and can target the mitochondria. The composite hydrogel is easy to prepare, easy to administrate and high in viscosity, has the characteristics of continuous drug release mode, minimum dosage frequency, low drug toxicity and the like, and is beneficial to being widely applied to treatment of periodontitis related diseases.

The invention discloses a zinc-selenium doped white calcium stone injectable hydrogel for treating melanoma and a preparation method of the zinc-selenium doped white calcium stone injectable hydrogel. The preparation method comprises the following steps: 1, preparing hydrophilic zinc-selenium doped white calcium stone; 2, preparing oxidized sodium alginate; and (3) dispersing the hydrophilic zinc-selenium-doped white phosphorus calcium stone into the oxidized sodium alginate solution, adding the carboxymethyl chitosan solution, and uniformly mixing to obtain the zinc-selenium-doped white phosphorus calcium stone injectable hydrogel for treating melanoma. The injectable hydrogel prepared by the invention has good injectability, self-healing property and biocompatibility, and is suitable for tumor wound models with any shape and depth; the composition has good effects of promoting normal cell proliferation and inhibiting tumor cell growth, and can be used for tumor postoperative treatment to inhibit tumor recurrence and promote surgical defective tissue repair.

Systems, compositions, and methods related to injectable hydrogels are generally described. In some embodiments, a composition comprises a first polymer and a plurality of particles comprising a second polymer capable of forming a hydrogel at elevated temperatures, such as body temperature. The plurality of particles (e.g., hydrogel particles) may comprise an active substance, such as a biological material and / or a therapeutic agent. Together, the first polymer and the second polymer may interact with each other (e.g., the first polymer may interpenetrate the second polymer, and / or the first polymer may cross-link with the second polymer) at elevated temperatures to form a hydrogel. Interactions between the first and second polymer, and / or between hydrophobic domains thereof, may facilitate the relatively slow and / or controlled release of the active substance. In some embodiments, the plurality of particles may have advantageously high loadings of biological materials (e.g., antibodies, proteins, peptides).

The invention discloses a gelatin-hyaluronic acid injectable hydrogel drug-carrying nanoparticle composite material as well as a preparation method and application thereof, relates to the technical field of biomedicine, and solves the problems that in the prior art, existing drugs for treating cartilage related diseases are difficult to deliver; the chronic inflammatory response in the articular cavity cannot be effectively controlled and cartilage cells cannot be protected at the same time, so that the application effect of the medicine is limited. The preparation method disclosed by the invention comprises the following steps: S1, obtaining a carnosine modified hyaluronic acid derivative Car-HA; s2, preparing nano particles (FNPs) loaded with fenofibrate; and S3, mixing the gelatin solution containing the FNPs with a Car-HA solution, adding transglutaminase into the mixed system, and carrying out an enzymatic cross-linking reaction to form the hydrogel FNPs-GelHA with a stable network structure. The CarHA and FNPs synergistic hydrogel strategy provided by the invention has good structural adjustability and drug adaptability, is suitable for delivery of various anti-inflammatory, anti-oxidation and cartilage repair drugs, and can be widely applied to local precise treatment of cartilage related diseases.

The invention discloses injectable hydrogel with a myocardial tissue repairing function as well as a preparation method and application of the injectable hydrogel, and relates to the technical field of medical materials. The preparation method of the injectable hydrogel comprises the following steps: carrying out a reaction on deferoxamine and DSPE-PEG-NHS, so as to obtain DSPE-PEG-DFO; the preparation method comprises the following steps: wrapping carvedilol with DSPE-PEG-DFO under the hydrophilic and hydrophobic action, so as to obtain a drug-loaded nano-micelle; the preparation method comprises the following steps: reacting a polymer containing amino or hydroxyl with methacrylic anhydride to obtain a methylacryloyl modified polymer; reacting the carboxyl-containing polymer with cysteamine hydrochloride to obtain a sulfydryl modified polymer; mixing the drug-loaded nano-micelle, the methylacryloyl modified polymer and the sulfydryl modified polymer, and reacting under ultraviolet radiation to obtain the injectable hydrogel. The hydrogel disclosed by the invention is good in biocompatibility, can release deferoxamine and carvedilol in a ladder manner, is matched with a myocardial repair process, and realizes a function of repairing damaged myocardial tissues.

The invention discloses injectable hydrogel for alveolar bone repair, the injectable hydrogel comprises a first component and a second component, the first component comprises 4-carboxyl-3-fluorophenylboronic acid modified carboxymethyl chitosan CMCS-FPBA and beta-tricalcium phosphate, and the second component comprises oxidized dextran, PPS-HA nano-micelle and curcumin. The invention also discloses a preparation method and application of the injectable hydrogel. The injectable hydrogel disclosed by the invention has the effects of resisting oxidation, resisting inflammation and promoting bone tissue regeneration, is high in biocompatibility, can be customized in a personalized manner, and can be used for repairing alveolar bones.

The invention belongs to the technical field of biomedical materials, and discloses pH-responsive injectable hydrogel as well as a preparation method and application thereof. Comprising the following steps: (1) dissolving sodium alginate in water to form a uniform solution; (2) adding a fat-soluble small molecule drug and Fe3O4 nanoparticles into the solution, carrying out high-speed shearing dispersion under an ice-water bath condition to form a drug / nano composite system, and standing; and (3) sequentially adding a calcium carbonate suspension and glucolactone into the drug / nano composite system, uniformly stirring, and incubating until the mixture is completely cured to obtain the pH-responsive injectable hydrogel. The hydrogel obtained by the invention not only has excellent injectability and pH response release performance, but also can remarkably improve the loading efficiency of fat-soluble drugs, and provides a new technical approach for realizing local anti-tumor treatment.

An injectable hydrogel for heart failure treatment with myocardial tissue repair function and its preparation method and use are disclosed. The hydrogel is prepared by chelating alginic acid and multivalent cations. The hydrogel is loaded with an active substance for repairing cardiac injury. The active substance is recombinant humanized collagen type III. The hydrogel is administrated into the left ventricle free wall by transendocardial injection. Implanting the hydrogel in the myocardium can increase the thickness of the left ventricular wall, adjust the stress of the ventricular wall, affect the morphology of the left ventricle, and prevent or reverse left ventricular enlargement. Further, the hydrogel is loaded with a new recombinant humanized collagen material that has the function of repairing cardiac tissue injury to further improve cardiac function and promote cardiac repair.

The invention provides application of injectable hydrogel in preparation of a medicine for treating myocardial infarction. The injectable hydrogel is obtained by mixing aniline tetramer grafted gelatin, adipic dihydrazide modified hyaluronic acid and an aldehyde group-containing metal polyphenol complex. The injectable hydrogel has antioxidant activity, conductivity and angiogenesis promoting activity performance, and myocardial repair is promoted through synergistic regulation and control.

The invention discloses a dual-network injectable hydrogel as well as a preparation method and application thereof. The hydrogel is methacrylated gelatin / oxidized hyaluronic acid loaded with metal polyphenol nano-particles, and the metal polyphenol nano-particles are copper-gallic acid nano-particles which contain quaternized chitosan coatings and are loaded with antibacterial peptide HHC36. After the hydrogel is injected into a periodontal pocket, the hydrogel can adapt to different defect shapes, and the CuGA-coated HHC36-coated QCS nanoparticles are released by responding to a periodontitis microenvironment, so that the effects of resisting periodontal pathogenic bacteria, removing local excessive ROS (reactive oxygen species), effectively promoting fibroblast proliferation, collagen deposition, extracellular matrix accumulation and angiogenesis and further promoting periodontal bone regeneration are achieved. The preparation process is simple, the injectable hydrogel is low in price and easy to obtain, the injectable hydrogel can be prepared through simple steps, and a new thought is provided for treatment of periodontitis.

The invention discloses injectable hydrogel for treating periodontitis and a preparation method of the injectable hydrogel. The injectable hydrogel is prepared from protocatechuic acid grafted carboxymethyl chitosan hydrogel and a zinc-metformin complex loaded in the protocatechuic acid grafted carboxymethyl chitosan hydrogel. The hydrogel aims to become a safe and effective treatment method so as to reduce oxidative stress and tissue damage caused by periodontitis. And the hydrogel is designed into an injectable form, so that the clinical operation is facilitated, and the comfort of a patient is improved. Therefore, the treatment effect and life quality of patients with chronic periodontitis are improved, and inconvenience and discomfort in the treatment process are reduced.

The invention discloses a visual multifunctional injectable hydrogel with endogenous and endogenous stimulation responsiveness as well as a preparation method and application of the visual multifunctional injectable hydrogel. The hydrogel is mainly prepared from oxygen vacancy molybdenum oxide nanoparticles Ce6-coated PEG-MoOx, transglutaminase and gelatin, wherein the oxygen vacancy molybdenum oxide nanoparticles Ce6-coated PEG-MoOx are loaded with a photosensitizer chlorin e6 and are modified by polyethylene glycol. The hydrogel disclosed by the invention can be applied to preparation of anti-inflammatory, anti-infection or wound repair promoting medicines, especially medicines for treating periodontitis or oral infection. The visible multifunctional injectable hydrogel with endogenous and endogenous stimulus responsiveness, which is constructed by the invention, can be developed through photoacoustic imaging, can play a role of a contrast agent, presents a morphological structure of an area in which the hydrogel is located, can eliminate negative oxidative stress of tissues, can efficiently and quickly kill bacteria, and can be used for preparing a medical dressing for treating endogenous and endogenous stimulus responsiveness. The inorganic signal molecules are controlled in a long-acting and controlled-release manner to play anti-inflammatory and angiogenesis promoting roles, so that tissue healing is promoted.

Provided herein are methods of preparing an engineered heart valve for implantation into a subject in need (e.g., a pediatric patient). For example, a porcine pulmonary valve can be decellularized and then recellularized with cells from the subject. Hydrogels can be used to facilitate cell delivery and growth within the sub-endothelial layer (e.g., spongiosa) of a heart valve, which is essential for long-term success of the implantation.

A nano-composite hydrogel for radiosensitization after breast-conserving surgery for breast cancer and a preparation method therefor. The nano-composite hydrogel comprises a hydrogel loaded with mesoporus gold nanoparticles M@AuNPs. The preparation method is as follows: The starting materials include a modified chitosan solution, a modified hyaluronic acid solution, and M@AuNPs. M@AuNPs are dispersed in the modified hyaluronic acid solution and the modified chitosan solution is isovolumetrically mixed with the modified hyaluronic acid solution to give the hydrogel. An injectable hydrogel encapsulating nanoparticles. The injectable hydrogel has a structure uniformly encapsulating outer-layer modified gold nanoparticles, and is capable of implementing immunotherapy by means of the targeted sustained-release of therapeutic drugs and meanwhile achieving ray energy accumulation due to the higher atomic number of the gold nanoparticles, thereby effectively killing tumor cells at the tumor bed position. The strategy effectively reduces the radiation dose in the whole breast radiotherapy, and is beneficial to protecting normal tissues of the breast outside the tumor bed.

The invention provides hydrogel, preparation of the hydrogel and medical dressing containing the hydrogel, CMC-PBA and HA-DA are used as hydrogel matrixes and are connected through boric acid ester bonds, and copper nano-enzyme (Cu NCs) chelated by EGCG is added into the hydrogel matrixes, so that the hydrogel (EGCG-Cu NPs) loaded with the copper nano-enzyme (injectable) is obtained. Wherein the CMC-PBA is a product obtained by reacting carboxymethyl chitosan (CMC) with carboxyl activated 4-carboxyphenylboronic acid (PBA), and the HA-DA is a product obtained by reacting carboxyl activated hyaluronic acid (HA) with dopamine hydrochloride (DA). The hydrogel can deeply promote wound recovery through in-vivo use, has good antioxidant activity and antibacterial activity, has extremely high active oxygen removal performance on necrotic cells of the wound, greatly accelerates the healing speed of the wound, brings clinical welfare to the wound, especially a chronic disease wound, and promotes the development of chronic wound diseases.

This invention relates to an injectable hydrogel, its preparation method, and its applications. It solves the technical problems of short half-life, rapid degradation, and inability to directly form bone by direct systemic injection of disulfiram in existing technologies. The hydrogel contains catecholized calcium alginate, disulfiram, and water. The catecholized calcium alginate contains calcium alginate, a catechol group, and calcium ions. The catechol group is coupled to the side chain of the calcium alginate. The mass percentage content of the catecholized calcium alginate is 0.5-5%; the mass percentage content of the disulfiram is 0.25-2%; and the balance is water. This invention can be used to prepare materials that promote alveolar bone repair and regeneration.

The invention relates to nervonic acid-loaded near-infrared light response type injectable hydrogel as well as a preparation method and application thereof, and belongs to the technical field of biological engineering. According to the invention, P (NIPAM-co-NHMAM) and a modified natural polymer material are combined to prepare a temperature-responsive hydrogel capable of realizing reversible volume shrinkage / expansion at a specific temperature, near-infrared light physiotherapy and irradiation are combined to damage local skin, and the hydrogel is stimulated to realize reversible volume deformation by controlling tissue temperature, so that the temperature-responsive hydrogel can be used for preparing the hydrogel with the reversible volume shrinkage / expansion at the specific temperature. Therefore, accurate and wireless space-time regulation and control of nervonic acid release behaviors are realized. Therefore, the nervonic acid loaded near-infrared light response type injectable hydrogel disclosed by the invention can realize efficient carrying and light response controllable release of nervonic acid, promotes functional recovery after spinal cord injury, and has a relatively good application prospect and research significance.

In some aspects, the present disclosure pertains to a hydrogel agitation and injection assembly, the assembly comprising a delivery device providing a barrel configured as a reservoir for an injectable hydrogel; and a shuttle disposed in the reservoir, where the shuttle is configured at least to translate along a longitudinal axis of the delivery device responsive to an application of a magnetic field to the shuttle, and where the shuttle includes an aperture extending entirely through the shuttle along the longitudinal axis of the delivery device.

The invention belongs to the technical field of biological medicine, and discloses an injectable hydrogel combined reagent, self-curing conductive hydrogel and application thereof. The injectable hydrogel combined reagent provided by the invention comprises a solution A and a solution B, the solution A is a first precursor solution formed by dissolving modified poloxamer PFUDAm and ammonium persulfate in deionized water; the solution B is a second precursor solution formed by dissolving N-isopropylacrylamide NIPAM, ferrous gluconate and PEDOT: PSS in deionized water, after the injectable hydrogel combined reagent is mixed in a duplex injection mode, PFUDAm, poly (N-isopropylacrylamide) and PEDOT: PSS are subjected to an oxidation-reduction reaction of ammonium sulfate and ferrous gluconate to initiate polymerization, and the self-curing conductive hydrogel is constructed. The self-curing conductive hydrogel has controllable curing time, and the self-curing conductive hydrogel has excellent swelling resistance, conductivity and good elasticity and toughness, and is expected to be combined with a cardiac pacemaker to be applied to treatment of arrhythmia.

This invention relates to a locally injectable hydrogel for treating pancreatic cancer, its preparation method, and its application. The hydrogel is prepared from raw materials comprising hyaluronic acid-dopamine and a radionuclide. Through extensive research and optimization, this invention has discovered that reacting hyaluronic acid-dopamine and a radionuclide in a suitable temperature and solvent, followed by mixing the resulting reaction solution with an alkaline sodium periodate solution and rapid stirring, successfully prepares a locally injectable hydrogel highly suitable for treating pancreatic cancer. The hydrogel is prepared under mild conditions, has a simple composition, and high safety. It effectively addresses the core bottlenecks in local radiotherapy for pancreatic cancer, such as poor stability of radionuclide carriers, short retention time, and uncontrollable release. Furthermore, it can reshape the body's immune microenvironment and enhance anti-tumor immune responses, significantly improving therapeutic efficacy. This has significant clinical implications for overcoming the current limitations in the treatment of locally advanced unresectable pancreatic cancer.

Provided are an injectable joint cavity hydrogel pharmaceutical composition and a method for preparing same. The hydrogel pharmaceutical composition comprises a gel particle and a drug loaded in the gel particle. The gel particle is formed by cross-linking hyaluronic acid or a salt thereof with fibroin via a cross-linking agent. The drug comprises an anti-inflammatory agent and / or a growth factor. The hydrogel pharmaceutical composition can treat a bone and joint-related disease by means of intra-articular injection.

The invention relates to the technical field of medical material performance testing, in particular to a performance testing system for injectable hydrogel, which is characterized in that an external testing environment characteristic parameter, a rheological characteristic parameter of a testing sample and a core temperature are acquired through a data acquisition module; calculating the viscous modulus and the elastic modulus of the test sample based on the rheological characteristic parameters through a data analysis module so as to judge whether the sample conforms to gelation dynamic characteristics or not; a standard evaluation module is used for extracting corresponding time points conforming to gelation dynamic characteristics so as to judge whether the performance test system conforms to the standard or not; analyzing the characteristic characterization value of the test environment through a compensation control module so as to judge whether the reason that the performance test system does not meet the standard is an environment reason or not; and determining a main interference reason based on the correlation coefficient of the test environment characteristic parameter and the sample core temperature, and starting compensation adjustment. According to the invention, the accuracy of the performance test system for injectable hydrogel is obviously improved.