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A technology of icodextrin and gel, applied in bandages, medical science, etc., can solve problems such as weak protective effect, small molecular weight, and inability to protect the film
Active Publication Date: 2020-10-23
HUAREN PHARMACEUTICAL CO LTD +3
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However, the molecular weight of α-glucan oligosaccharides is small, so it cannot for
Method used
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[0027] (1) The dressings obtained in the above examples were sealed and left for a week at normal temperature and pressure, and the state of the auxiliary materials was observed every 6 hours. The obtained dressings remained in a stable gel state without delamination or flocculation.
[0028] (2) Take 18 rats, smear or spray the gel dressing obtained in the above examples on the superficial wounds on the right hind legs of the rats (all wounds are 1 cm), apply once every 12 hours, and take 3 groups of wounds Rats healed naturally were used as the control group, and each group contained 3 rats with wounds. The experimental results obtained are shown in the following table:
[0029]
[0030]...
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Abstract
The invention provides a gel dressing containing icodextrin. The dressing is prepared by using water for injection or purified water as a carrier and adding the icodextrin, carbomer or carboxymethylcellulose sodium, triethanolamine, butanediol, caprylhydroxamic acid, 3-[2-(Ethylhexyl)oxyl]-1,2-propandiol, 1,2-hexanediol, flavoring agent, etc. The gel dressing containing icodextrin provided by theinvention is in gelatinous form, and can be applied to new scars and minimally invasive wounds to prevent scar hyperplasia and external pollution, reduce the probability of scar formation and avoid pigmentation scars.
Description
technical field [0001] The invention belongs to the field of medical devices, in particular to a non-sterile gel dressing containing icodextrin. Background technique [0002] In the medical field, dressings generally refer to external materials that can protect wounds, prevent secondary infection and heat loss. At present, there are mainly traditional gauze dressings and modern dressings. Modern dressings include sodium alginate / calcium dressings, interactive dressings, silver Ionic dressings, foam dressings and gel dressings, etc. [0003] Glucan is a homopolysaccharide composed of glucose as a monosaccharide, which is divided into α-glucan and β-glucan, and each glucan has a variety of bond combinations. As an active ingredient in skin care products, dextran has a long history in the West. Families in many European and American countries are used to bathing infants and young children with water soaked in oatmeal to relieve and prevent eczema; the elderly are also used to...
Claims
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