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Coating preparation for ureter catheter

A catheter and ureter technology, which is applied in the field of ureter catheter coating preparations, can solve the problems of low hydrophilicity, lubricity and antibacterial effect of the surface coating of the catheter, adhesion of the catheter and the urethral mucosa, and urinary catheterization. The problem of single coating on the surface of the tube can achieve excellent physiological inertia, long-lasting antibacterial properties, and reduce urinary tract infections.

Inactive Publication Date: 2020-12-11
湖南利德森医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The surface coating of the urinary catheter is relatively simple and is limited to simple antibacterial, but the hydrophilicity, lubricity and antibacterial effect of the surface coating of the urinary catheter are relatively low. After a period of use, the antibacterial effect will gradually decrease. It has antibacterial effect in a short period of time, and adhesion between the catheter and the urethral mucosa will easily cause infection between the catheter and the urethra

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The invention provides a technical solution: a coating preparation for ureteral catheters, including the following coatings: antibacterial drug coating, hydrophilic polymer PVP layer, silicone modified layer, biofilm layer, Nano silver coating and hydrophilic lubricating coating;

[0029] The biofilm layer comprises raw materials of the following mass components: 25 parts of inorganic antibacterial agents and 10 parts of anti-adhesive agents;

[0030] The antibacterial drug coating comprises raw materials of the following mass components: 10 parts of antibacterial solution, 1 part of biguanide antibacterial agent and 60 parts of ethanol;

[0031] Nano-silver coatings include nano-silver and silver-containing coatings;

[0032] The hydrophilic macromolecular PVP layer includes raw materials of the following quality components: 20 parts of silver ion antibacterial agent and 5 parts of lidocaine surface anesthesia component gel, and the hydrophilic macromolecular PVP laye...

Embodiment 2

[0043] The invention provides a technical solution: a coating preparation for ureteral catheters, including the following coatings: antibacterial drug coating, hydrophilic polymer PVP layer, silicone modified layer, biofilm layer, Nano silver coating and hydrophilic lubricating coating;

[0044] The biofilm layer comprises raw materials of the following mass components: 35 parts of inorganic antibacterial agents and 15 parts of anti-adhesive agents;

[0045] The antibacterial drug coating comprises raw materials of the following mass components: 15 parts of antibacterial solution, 3 parts of biguanide antibacterial agent and 75 parts of ethanol;

[0046] Nano-silver coatings include nano-silver and silver-containing coatings;

[0047] The hydrophilic macromolecular PVP layer includes raw materials of the following quality components: 35 parts of silver ion antibacterial agent and 9 parts of lidocaine surface anesthesia component gel, and the hydrophilic macromolecular PVP lay...

Embodiment 3

[0058] The invention provides a technical solution: a coating preparation for ureteral catheters, including the following coatings: antibacterial drug coating, hydrophilic polymer PVP layer, silicone modified layer, biofilm layer, Nano silver coating and hydrophilic lubricating coating;

[0059] The biofilm layer comprises raw materials of the following mass components: 30 parts of inorganic antibacterial agent and 12 parts of anti-adhesive agent;

[0060] The antibacterial drug coating comprises raw materials of the following mass components: 12 parts of antibacterial solution, 2 parts of biguanide antibacterial agent and 65 parts of ethanol;

[0061] Nano-silver coatings include nano-silver and silver-containing coatings;

[0062] The hydrophilic macromolecular PVP layer comprises raw materials of the following quality components: 21 parts of silver ion antibacterial agent and 8 parts of lidocaine surface anesthesia component gel, and the hydrophilic macromolecular PVP laye...

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PUM

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Abstract

The invention discloses a coating preparation for a ureter catheter. The coating preparation comprises the following cladding coatings of an antibacterial drug coating, a hydrophilic polymer PVP layer, an organic silicon modified layer, a biofilm layer, a nano-silver coating and a hydrophilic lubricating coating, wherein the biofilm layer is prepared from the following raw materials in parts by mass of 25-35 parts of an inorganic antibacterial agent and 10-15 parts of an anti-adhesion agent; and the antibacterial drug coating is prepared from the following raw materials in parts by mass of 10-15 parts of an antibacterial solution, 1-3 parts of a biguanide antibacterial agent and 60-75 parts of ethanol. Related urinary tract infection of the catheter is reduced through the nano-silver coating, the organic silicon modified layer can control slow release of the nano-silver coating, and the biological layer and the antibacterial bioactive polymer coating are used for blocking the immune effect of a body, so that the outer surface layer of the catheter coating has lasting antibacterial property, and the situation that infection between the catheter and the urethra easily occurs when thecatheter is adhered to the urethra mucous membrane is avoided.

Description

technical field [0001] The invention relates to the technical field of ureteral catheters, in particular to a coating preparation for ureteral catheters. Background technique [0002] As we all know, the ureter connects to the renal pelvis at the top and connects to the bladder at the bottom. It is a pair of slender tubes, which are flat and cylindrical, with an average diameter of 0.5 to 0.7 cm. The adult ureter has a total length of 25 to 35 cm, located in the retroperitoneum, and descends vertically along the front of the medial side of the psoas major muscle into the pelvis. The ureter has three strictures: one at the transition between the renal pelvis and the ureter, one across the entrance to the pelvis pelvis, and a final one just inside into the bladder wall. These stenosis are places where stones, blood clots and necrotic tissue tend to stay; [0003] China Publicly Authorized Invention: Preparation Method of Antibacterial Coating on the Surface of Urinary Cathet...

Claims

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Application Information

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IPC IPC(8): A61L29/12A61L29/16A61L29/04A61L29/02
CPCA61L29/02A61L29/041A61L29/16A61L2300/402A61L2300/404A61L2300/604A61L2300/61C08L39/06
Inventor 雷斌宝雷斌磊邓攀
Owner 湖南利德森医疗器械有限公司