Desensitization paste as well as preparation method and application thereof

A technology of desensitizing paste and sensitizing paste, which is applied in anti-inflammatory agents, pharmaceutical formulas, aerosol delivery, etc., can solve problems such as complex pathogenic factors of dental caries, achieve good tooth desensitization and antibacterial effects, and improve tooth decay. Bacteria, plaque removal effect

Active Publication Date: 2020-12-15
SICHUAN TIANFU FINE CHEM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the complex pathogenic factors of dental caries, comprehensive caries prevention measures must be adopted in order to prevent or reduce the occurrence of dental caries.

Method used

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  • Desensitization paste as well as preparation method and application thereof
  • Desensitization paste as well as preparation method and application thereof
  • Desensitization paste as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The preparation of embodiment 1 desensitization paste

[0029] S1: 50 parts of calcium powder, 5 parts of strontium chloride, 5 parts of potassium nitrate, 10 parts of sodium fluoride, 0.3 parts of Galla gall extract, 0.05 parts of chlorhexidine acetate, 5 parts of honeycomb extract, and 0.8 parts of carboxymethyl cellulose 2 parts, 2 parts of sodium lauryl sulfate, mixed evenly, dispersed in 20 parts of glycerin;

[0030] S2: 0.5 parts of gum arabic, 8 parts of sorbitol and 0.8 parts of turpentine were added to the dispersion system and mixed evenly to obtain a desensitizing paste.

Embodiment 2

[0031] The preparation of embodiment 2 desensitization paste

[0032] S1: 60 parts of calcium powder, 15 parts of strontium chloride, 15 parts of potassium nitrate, 15 parts of sodium fluoride, 0.5 parts of gallnut extract, 0.3 parts of chlorhexidine acetate, 10 parts of honeycomb extract, 1.5 parts of carboxymethyl cellulose 6.5 parts of sodium lauryl sulfate, mixed evenly, dispersed in 30 parts of glycerin;

[0033] S2: 1 part of gum arabic, 15 parts of sorbitol and 1.5 parts of turpentine were added to the dispersion system and mixed evenly to obtain a desensitizing paste.

Embodiment 3

[0034] The preparation of embodiment 3 desensitization paste

[0035] S1: 50 parts of calcium powder, 10 parts of strontium chloride, 10 parts of potassium nitrate, 10 parts of sodium fluoride, 0.5 parts of gallnut extract, 0.1 part of chlorhexidine acetate, 5 parts of honeycomb extract, 1 carboxymethyl cellulose 3 parts and 3 parts of sodium lauryl sulfate were mixed evenly and dispersed into 20 parts of glycerin;

[0036]S2: 1 part of gum arabic, 10 parts of sorbitol and 1 part of turpentine were added to the dispersion system and mixed evenly to obtain a desensitizing paste.

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Abstract

The invention discloses desensitization paste. The desensitization paste is prepared from the following components in parts by weight of 0.3-0.5 part of gallnut extract, 0.05-0.3 part of chlorhexidineacetate, 5-10 parts of honeycomb extract liquor, 50-60 parts of calcium powder, 5-15 parts of strontium chloride, 5-15 parts of potassium nitrate, 10-15 parts of sodium fluoride and 30-56 parts of pharmaceutically acceptable auxiliary materials. The gallnut traditional Chinese medicine active extract is added into the desensitization paste provided by the invention, so that the desensitization paste has a convergence effect and a protein precipitation effect, can block and seal dentinal tubules, and can be used for desensitizing fundamentally. Besides, the combined application of the gallnuttraditional Chinese medicine active ingredients, chlorhexidine acetate and the honeycomb extract liquor has a remarkable synergistic effect, can greatly improve the desensitization and sterilization effects of teeth of the product, particularly has a remarkable inhibition effect on streptococcus mutans forming decayed teeth, and plays a role in preventing and treating various oral diseases.

Description

technical field [0001] The invention belongs to the technical field of oral health care, and in particular relates to a desensitizing paste for preventing and / or treating oral diseases and a preparation method thereof. Background technique [0002] As people's material living standards have been significantly improved, the awareness of oral health care has also been continuously improved, and people have become more and more concerned about dental disease prevention, dental treatment, and dental health care. The human oral cavity is a relatively complex internal environment, containing a large number of harmful bacteria. If it is not properly cared for, it is prone to dentin hypersensitivity, oral ulcers, bleeding gums, gingivitis and many other problems, which will affect patients' eating and daily life. [0003] Dentin hypersensitivity is a subjective symptom caused by external stimuli on exposed dentin. Symptoms of tooth soreness and pain. Among oral diseases, dentine h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/64A61K9/06A61P1/02A61P7/04A61P29/00A61P37/08A61K31/155A61K33/00A61K33/06A61K33/14A61K33/16
CPCA61K35/64A61K31/155A61K33/06A61K33/14A61K33/00A61K33/16A61K9/06A61P37/08A61P1/02A61P7/04A61P29/00A61K2300/00
Inventor 王崇福王葵
Owner SICHUAN TIANFU FINE CHEM CO LTD
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