Preparation of polyethylene glycol sodium potassium oral pharmaceutical preparation
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A technology of polyethylene glycol sodium potassium powder and polyethylene glycol sodium potassium powder, which is applied in the direction of drug combinations, pharmaceutical formulas, medical preparations with non-active ingredients, etc., and can solve problems such as long dissolution time, trouble taking, and patient discomfort , to achieve the effect of fast dissolution
Inactive Publication Date: 2021-03-16
TIANJIN PRECEDE MEDICAL TRADE
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[0015] The polyethylene glycol sodium potassium powder or granule disclosed in the prior art is used to dissolve the preparation in water and then take it. If the amount of water is large, the powder or granule is easier to dissolve, but the large amount of water will cause discomfort to the patient. NuLYTELY's products require 4L of water
Mervicel belongs to the category with less water. Dissolve 13.8 grams per pack in about 125ml of water and then take it.
Method used
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Embodiment 1
[0042] Preparation of polyethylene glycol sodium potassium powder:
[0043] Each 15g serving contains the following ingredients:
[0044]
[0045]
[0046] The preparation method is as follows:
[0047] (1) Weigh sodium bicarbonate, sodium chloride, potassium chloride, xylitol, polyethylene glycol 3350, put them into a blender, spray an appropriate amount of absolute ethanol to moisten under stirring, and stir continuously for 30 minutes after wetting, take out;
[0048] (2) fully dry, the coarse powder after drying is through grinding and pulverizing, crosses 80 mesh sieves, obtains powder;
[0049] (3) Ready to pack.
Embodiment 2
[0051] Preparation of polyethylene glycol sodium potassium powder:
[0052] Each 15g serving contains the following ingredients:
[0053]
[0054] The preparation method is as follows:
[0055] (1) Weigh sodium bicarbonate, sodium chloride, potassium chloride, xylitol, polyethylene glycol 3350, and orange essence into a blender, spray an appropriate amount of absolute ethanol to moisten under stirring, and stir continuously for 30 minutes after wetting. minutes, take out;
[0056] (2) fully dry, the coarse powder after drying is through grinding and pulverizing, crosses 80 mesh sieves, obtains powder;
[0057] (3) Ready to pack.
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Abstract
The invention relates to a preparation method of a polyethylene glycol sodium potassium oral pharmaceutical preparation. The method comprises the following steps of (1) weighing sodium bicarbonate, sodium chloride, potassium chloride, xylitol and polyethylene glycol 3350, putting the components into a stirrer, spraying a proper amount of absolute ethyl alcohol in stirring for wetting, performing continuous stirring for 30 minutes after wetting, and taking out a mixture; (2) performing full drying, grinding and crushing dried coarse powder, and sieving the grounded and crushed powder with an 80-mesh sieve to obtain powder; and (3) performing sub-packaging to obtain the polyethylene glycol sodium potassium oral pharmaceutical preparation.
Description
technical field [0001] The invention relates to the preparation of a pharmaceutical preparation, in particular to the preparation of a sodium potassium polyethylene glycol oral pharmaceutical preparation. Background technique [0002] Polyethylene glycol sodium potassium powder, a medicine for treating constipation, ingredients: each contains [0003] [0004] The following ingredients are included in the flavoring: acacia solids, maltodextrin, orange oil, lemon oil, citral, citric acid and water. [0005] The polyethylene glycol sodium potassium powder described above has a trade name of Movic, which was launched in the UK on December 18, 1995, and domestic imported products are listed. Similar products listed abroad also include polyethylene glycol sodium potassium powder with trade name: GoLYTELY and trade name: NuLYTELY. [0006] Polyethylene glycol sodium potassium powder has a laxative effect due to the penetration of polyethylene glycol in the intestinal tract, a...
Claims
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Application Information
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