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Traditional Chinese medicine ointment for promoting wound healing and reducing scar formation and preparation method of traditional Chinese medicine ointment

A technology of wound healing and traditional Chinese medicine ointment, which is applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, drug combinations, etc., and can solve problems such as large side effects, slow effects, and high treatment prices

Active Publication Date: 2021-04-27
SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chronic wound healing and scar residue after healing have always been an international medical problem, mainly including surgical resection, laser removal, silicone therapy, and compression therapy. and economic pressure, so early intervention in the scar formation stage is of great significance to reduce scar formation

Method used

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  • Traditional Chinese medicine ointment for promoting wound healing and reducing scar formation and preparation method of traditional Chinese medicine ointment
  • Traditional Chinese medicine ointment for promoting wound healing and reducing scar formation and preparation method of traditional Chinese medicine ointment
  • Traditional Chinese medicine ointment for promoting wound healing and reducing scar formation and preparation method of traditional Chinese medicine ointment

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1 prepares the traditional Chinese medicine ointment that promotes wound healing and reduces scar formation

[0034] It is prepared from the following raw materials in parts by weight: 4 parts of salvia miltiorrhiza, 1 part of honeysuckle, 2 parts of lovage, forsythia, cortex mulberry and achyranthes bidentata each, and 15 parts of pure suet.

[0035] The preparation method is:

[0036] (1) Take Danshen decoction pieces (dried to constant weight in advance), pulverize (pass through 80 mesh sieve), add appropriate amount of water to moisten and mix well, and set aside;

[0037] (2) Get Flos Lonicerae Flos Lonicerae, Lovage, Forsythia, Cortex Mori and Achyranthes Radix Radix, pulverize (through 80 mesh sieve), add appropriate amount of 95% ethanol solution (volume percentage), decoct until ethanol is completely volatilized, obtain medicinal residues, stand-by;

[0038] (3) Mix the medicinal dregs in step (1) with the uniformly moistened salvia miltiorrhiza pow...

Embodiment 2

[0039] Embodiment 2 prepares the traditional Chinese medicine ointment that promotes wound healing and reduces scar formation

[0040] It is prepared from the following raw materials by weight: 3 parts of Danshen decoction pieces, 2 parts of honeysuckle, 3 parts of Duhuo, 3 parts of forsythia, 3 parts of Cortex Mori, 3 parts of Achyranthes bidentata and 12 parts of suet.

[0041] Others are with embodiment 1.

Embodiment 3

[0042] Embodiment 3 prepares the traditional Chinese medicine ointment that promotes wound healing and reduces scar formation

[0043] It is prepared from the following raw materials by weight: 2 parts of Danshen decoction pieces, 2 parts of honeysuckle, 4 parts of Duhuo, 4 parts of forsythia, 4 parts of Cortex Mori, 4 parts of Achyranthes bidentata, and 10 parts of suet.

[0044] Others are with embodiment 1.

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Abstract

The invention discloses a traditional Chinese medicine ointment for promoting wound healing and reducing scar formation. The traditional Chinese medicine ointment is prepared from the following raw material medicines in parts by weight: 2-4 parts of salvia miltiorrhiza decoction pieces, 1-2 parts of flos lonicerae, 2-4 parts of radix angelicae pubescentis, 2-4 parts of fructus forsythiae, 2-4 parts of cortex mori radicis, 2-4 parts of radix achyranthis bidentatae and 10-15 parts of mutton tallow. The traditional Chinese medicine ointment disclosed by the invention has obvious effects on promoting wound healing and reducing scar formation. By influencing secretion of related growth factors (EGF, VEGF-alpha, TGF-beta and the like), the level of tumor necrosis factors is improved, and aggregation of neutrophils and macrophages is promoted, so that the inflammatory reaction process is reduced, and the wound is prevented from being in an inflammatory state for a long time. Moreover, the bacterial infection (staphylococcus aureus, pseudomonas aeruginosa, proteusbacillus vulgaris and the like) is resisted, and the purposes of promoting wound healing, reducing excessive proliferation of fibroblasts in regenerated tissues and reducing scar formation in the wound healing stage are achieved.

Description

technical field [0001] The invention relates to a traditional Chinese medicine plaster for promoting wound healing and reducing scar formation and a preparation method thereof, belonging to the technical field of research and development of traditional Chinese medicines. Background technique [0002] Wound healing is a physiological response to skin damage, including four stages: hemostasis, inflammation, regeneration, and remodeling. The intractable scars formed after wound healing seriously affect the physical and mental health of patients. The intractable scars are mainly caused by excessive angiogenesis, excessive contraction of granulation tissue and excessive proliferation of fibroblasts. In particular, the skin wounds of patients with burns and hyperglycemia usually heal slowly, and the intractable scars are relatively serious. Chronic wound healing and scar residue after healing have always been an international medical problem, mainly including surgical resection, ...

Claims

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Application Information

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IPC IPC(8): A61K36/634A61K9/06A61K47/44A61P17/02
CPCA61K36/537A61K36/355A61K36/232A61K36/634A61K36/605A61K36/21A61K9/06A61K9/0014A61K47/44A61P17/02A61K2236/333A61K2300/00Y02A50/30
Inventor 刘谦
Owner SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE
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