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Pharmaceutical composition for treating rheumatoid arthritis, preparation method and application thereof

A composition and arthritic technology are applied in the field of pharmaceutical compositions for the treatment of rheumatoid arthritis and the field of preparation thereof, which can solve the problems of high cost, need to be further improved, and the effect of rheumatoid arthritis is not significant enough, and achieve low cost, Good application prospect, good therapeutic effect

Active Publication Date: 2021-04-30
CHENGDU MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Patent CN1362068A discloses a drug for treating rheumatoid arthritis with black snake, scorpion, epimedium, tripterygium wilfordii, Aconitum aconitum, etc. as raw materials. The drug can improve microcirculation, enhance spine, joints and their surrounding areas The blood supply of the tissue can promote the absorption of inflammation in the spine, joints and surrounding tissues, and reduce the accumulation of pain-causing substances, but the effect still needs to be further improved
Patent CN104523972A discloses a pharmaceutical composition for treating rheumatoid arthritis, which also has a certain effect on rheumatoid arthritis, but it involves expensive drugs such as pangolins, and the cost is high
[0005] It can be seen that the drugs for the treatment of rheumatoid arthritis in the prior art have problems such as insufficient effect and high cost

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1, the preparation of pharmaceutical composition of the present invention

[0024] 1. Raw material formula: Astragalus 15g, Radix Glycyrrhizae 9g, Caulis Spatholobus 15g, Paeoniae Alba 12g, Duhuo 12g, Tangerine Peel 9g, Angelica 9g, Black Snake 10g, Scorpion 3g, Angelica 9g, Honeycomb 3g, Epimedium 10g, Clematis 12g, Dodder 12g, Tripterygium wilfordii 10g, Coix seed 10g, Jiao Sanzha 15g, Chinese yam 15g.

[0025] 2. Preparation method: take the above-mentioned raw material formula, mix it evenly, and grind it into powder to obtain the pharmaceutical composition of the present invention.

Embodiment 2

[0026] Embodiment 2, the preparation of pharmaceutical composition of the present invention

[0027] 1. Raw material formula: Astragalus 8g, Radix Glycyrrhizae 3g, Caulis Spatholobus 3g, Paeoniae Alba 3g, Duhuo 3g, Tangerine Peel 3g, Angelica 3g, Snake 3g, Scorpion 1g, Angelica dahurica 3g, Honeycomb 1g, Epimedium 3g, Clematis 3g, Dodder 3g, Tripterygium wilfordii 1g, Coix seed 3g, Jiao Sanzha 3g, Chinese yam 3g.

[0028] 2, preparation method: with embodiment 1.

Embodiment 3

[0029] Embodiment 3, the preparation of pharmaceutical composition of the present invention

[0030] 1. Raw material formula: Astragalus 20g, Radix Glycyrrhiza 12g, Caulis Spatholobus 20g, Paeoniae Alba 15g, Duhuo 15g, Tangerine Peel 12g, Angelica 12g, Snake 12g, Scorpion 6g, Angelica dahurica 12g, Honeycomb 9g, Epimedium 20g, Clematis 15g, Dodder 20g, Tripterygium wilfordii 12g, Coix seed 25g, Jiao Sanzha 25g, Chinese yam 25g.

[0031] 2, preparation method: with embodiment 1.

[0032] The beneficial effects of the pharmaceutical composition of the present invention are demonstrated below through specific test examples.

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PUM

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Abstract

The invention provides a pharmaceutical composition for treating rheumatoid arthritis, a preparation method and application thereof, and belongs to the field of traditional Chinese medicines. The pharmaceutical composition is a preparation prepared from the following raw material medicines in parts by weight: 8-20 parts of astragalus membranaceus, 3-12 parts of honey-fried licorice root, 3-20 parts of caulis spatholobi, 3-15 parts of radix paeoniae alba, 3-15 parts of radix angelicae pubescentis, 3-12 parts of pericarpium citri reticulatae, 3-12 parts of angelica sinensis, 3-12 parts of zaocys dhumnade, 1-6 parts of scorpion, 3-12 parts of radix angelicae, 1-9 parts of honeycomb, 3-20 parts of herba epimedii, 3-15 parts of radix clematidis, 3-20 parts of semen cuscutae, 1-12 parts of tripterygium wilfordii, 3-25 parts of semen coicis, 3-25 parts of scorched hawthorn fruit and 3-25 parts of Chinese yam. According to the invention, all the medicinal materials of the composition are precise and appropriate in compatibility, play a synergistic effect together, have the effects of tonifying the kidney, dredging collaterals, dispelling wind, relieving pain and removing dampness to relieve pain, can treat arthralgia, joint swelling and pain, waist and knee pain, flaccidity and weakness, unfavorable flexion and extension of limbs or numbness, hand and foot contracture and qi and blood stagnation, and have a good treatment effect on rheumatoid arthritis and low recurrence rate; and the pharmaceutical composition is low in cost and excellent in application prospect.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition for treating rheumatoid arthritis, a preparation method and application thereof. Background technique [0002] Rheumatoid arthritis (RA) is a chronic systemic disease of unknown etiology mainly characterized by inflammatory synovitis. Autoimmune disease with erosive arthritis as the main symptom. It is characterized by polyarticular, symmetrical, and aggressive arthritis of the small joints of the hands and feet, often accompanied by involvement of extra-articular organs and positive serum rheumatoid factor, which can lead to joint deformities and loss of function. The pathogenesis of RA may be related to heredity, infection, and sex hormones. The pathology of RA arthritis mainly includes the proliferation of synovial lining cells, the infiltration of a large number of inflammatory cells in the interstitium, the neogenesis of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P29/00A61P19/02A61K35/583A61K35/646A61K35/64
CPCA61K36/481A61K36/484A61K36/486A61K36/71A61K36/65A61K36/232A61K36/752A61K35/583A61K35/646A61K35/64A61K36/296A61K36/716A61K36/39A61K36/43A61K36/37A61K36/8994A61K36/734A61K36/8945A61P29/00A61P19/02A61K2236/331A61K2300/00
Inventor 党万太徐丹周京国周建
Owner CHENGDU MEDICAL COLLEGE
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