Graphene/calcium phosphate ceramic composite scaffold with antibacterial function and preparation method thereof

Abstract

The invention belongs to the technical field of biomedical materials, and discloses a graphene / calcium phosphate ceramic composite scaffold with an antibacterial function and a preparation method thereof. The preparation method comprises the following steps: placing porous calcium phosphate ceramic in a graphene-based material solution with a certain concentration, adsorbing graphene on the surface and in pores of the porous calcium phosphate ceramic through vacuum infusion, and drying to obtain the graphene / calcium phosphate ceramic composite scaffold. The graphene / calcium phosphate ceramic composite scaffold prepared by the method not only has good bone induction performance, but also has good antibacterial activity, and is expected to have a wide application prospect in clinical infectious bone defect regeneration and repair.

Description

technical field

[0001] The invention belongs to the technical field of biomedical materials, and in particular relates to a graphene / calcium phosphate ceramic composite bracket with antibacterial function and a preparation method. Background technique

[0002] Calcium phosphate bioceramics are widely used in the field of bone repair due to their excellent biological effects such as good biocompatibility, osteoconductivity and osteoinductivity. Bone defects caused by clinical trauma are often accompanied by wound contamination or infection symptoms, and conventional bone repair materials often fail to repair bone due to secondary infection. As the clinical problem of bacterial drug resistance becomes more and more prominent, higher requirements are put forward for the antibacterial properties of bone repair materials. Therefore, on the basis of optimizing the osteoinductive ability of calcium phosphate ceramics, it is of great significance to optimize the modification method...

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