The invention provides a multi-center radiotherapy plan generation method and device,
electronic equipment and a computer readable storage medium, and the method comprises the steps: receiving coordinates,
radiation field parameters, positioning
modes and unified
dose constraints of a plurality of treatment centers, and receiving a medical image, a target region and an organ-at-risk contour of a patient; establishing a multi-center collaborative optimization model; according to the unified
dose constraint optimization multi-center collaborative optimization model, generating a radiotherapy total plan including three-dimensional
dose distribution; splitting the total plan into a plurality of sub-plans; and performing
dose verification on the sub-plans, and outputting the sub-plans passing the
dose verification as
executable sub-plans to the treatment equipment. According to the method, the multi-center collaborative optimization model is optimized according to the unified dose constraint to generate the radiotherapy total plan containing the three-dimensional
dose distribution, and the dose constraint does not need to be repeatedly set and the placement
verification does not need to be implemented for multiple times in the plan
generation process, so that the radiotherapy time is shortened, and the dose deviation risk is reduced. Besides, the plurality of treatment centers are uniformly optimized, so that the dose interference risk of each
treatment center can be reduced, and the situation that cold and hot spots are formed due to non-uniform dose superposition and the safety of organs is affected is avoided.