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Antibacterial composition, preparation and application thereof

A technology of composition and extract, which is applied in the field of daily chemicals, can solve the problems of bacterial drug resistance, reduced antibacterial effect, strong irritation, etc., and achieves a wide antibacterial (antibacterial) spectrum, long shelf life, and fast antibacterial Effect

Inactive Publication Date: 2021-06-18
立康荣健(北京)生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, the antibacterial agents on the market are mainly chemical components, which have certain toxicity and strong irritation. Bacteria will develop drug resistance after long-term use, and the antibacterial effect will decrease.

Method used

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  • Antibacterial composition, preparation and application thereof
  • Antibacterial composition, preparation and application thereof
  • Antibacterial composition, preparation and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The present embodiment provides a kind of bacteriostatic composition, contains the raw material component of following weight portion:

[0029] 0.5 parts by weight of lysozyme, 0.1 parts by weight of ethyl lauroyl arginine hydrochloride, 0.06 parts by weight of ε-polylysine, 5 parts by weight of glycerin, and 95 parts by weight of purified water;

[0030] The preparation method of antibacterial composition described in the present embodiment is as follows:

[0031] Weigh each raw material separately, first add lauroyl arginine ethyl ester hydrochloride to purified water, stir for 15 minutes to completely dissolve, then add ε-polylysine, lysozyme, glycerin in sequence, and adjust the pH to 3.0 with citric acid , that is.

Embodiment 2

[0033] The present embodiment provides a kind of bacteriostatic composition, contains the raw material component of following weight portion:

[0034] 0.1 parts by weight of lysozyme, 0.3 parts by weight of ethyl lauroyl arginine hydrochloride, 0.2 parts by weight of ε-polylysine hydrochloride, 0.3 parts by weight of honeysuckle extract, 0.5 parts by weight of Scutellaria baicalensis extract, Radix Radix Radix 0.2 parts by weight, 99 parts by weight of purified water;

[0035] The preparation method of antibacterial composition described in the present embodiment is as follows:

[0036] Weigh each raw material separately, first add lauroyl arginine ethyl ester hydrochloride to purified water, stir for 20 minutes to completely dissolve, then add ε-polylysine, lysozyme, honeysuckle extract, Scutellaria baicalensis extract, Radix isatidis extract, adjust the pH to 5.0 with sodium hydroxide, and obtain it.

Embodiment 3

[0038] The present embodiment provides a kind of bacteriostatic composition, contains the raw material component of following weight portion:

[0039] 2 parts by weight of lysozyme, 2 parts by weight of ethyl lauroyl arginine hydrochloride, 0.5 parts by weight of ε-polylysine sulfate, 5 parts by weight of propolis, and 91 parts by weight of purified water;

[0040] The preparation method of antibacterial composition described in the present embodiment is as follows:

[0041] Weigh each raw material separately, first add lauroyl arginine ethyl ester hydrochloride to purified water, stir for 40 minutes to completely dissolve, then add ε-polylysine, lysozyme, propolis in turn, and adjust the pH to 6.2, that is.

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PUM

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Abstract

The invention relates to an antibacterial composition, a preparation and application thereof. The antibacterial composition comprises the following raw material components in parts by weight: 0.1-2 parts of lysozyme, 0.1-2 parts of ethyl lauroyl arginate hydrochloride, and 0.02-0.5 part of epsilon-polylysine and salt thereof and / or modified epsilon-polylysine and salt thereof. The antibacterial composition has the characteristics of safe raw materials, high efficiency in use, no irritation, no sensitization, tolerance and stable antibacterial effect, can be used for antibacterial disinfection of multiple purposes such as skin, oral cavity, mucosa, air and object surface, and can also be used for medical dressings and preparation of medicines with antibacterial effect.

Description

technical field [0001] The invention belongs to the technical field of daily chemicals, and in particular relates to an antibacterial composition, its preparation and application. Background technique [0002] At present, the antibacterial agents on the market are mainly chemical components, which have certain toxicity and strong irritation. Bacteria will develop drug resistance after long-term use, and the antibacterial effect will decrease. . [0003] iiMedia Consulting research found that with the continuous improvement of the economic environment and people's living standards, the country pays more attention to medical and health care, health investment continues to increase, residents' health awareness continues to increase, and people's requirements for sanitation and disinfection products are also getting higher and higher. , in addition to effectiveness, security requirements are getting higher and higher. Contents of the invention [0004] The object of the pres...

Claims

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Application Information

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IPC IPC(8): A61K38/47A61K31/223A61K31/785A61K36/539A61K36/8964A61P31/04A61P31/10A01N63/50A01N47/44A01N37/46A01P1/00A01P3/00A61L15/44A61K35/644A61K31/045
CPCA01N37/46A01N47/44A61K31/045A61K31/223A61K31/785A61K35/64A61K35/644A61K36/195A61K36/315A61K36/355A61K36/489A61K36/539A61K36/57A61K36/634A61K36/708A61K36/718A61K36/739A61K36/756A61K36/79A61K36/8964A61K38/47A61L15/44A61L2300/204A61L2300/254A61L2300/404A61P31/04A61P31/10A01N63/50C12Y302/01017A61K2300/00
Inventor 陈安军王天琪
Owner 立康荣健(北京)生物医药科技有限公司
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