Anti-allergy polishing paste containing potassium calcium phosphosilicate bioglass

A bio-glass, potassium phosphosilicate technology, applied in the field of dental polishing, can solve the problems of dental fluorosis and skeletal fluorosis, the anti-sensitivity effect is not long-lasting, toxic and side effects, etc., to inhibit bacteria, whitening effect and taste improvement, Effects without toxic side effects

Active Publication Date: 2021-06-22
佛山市诺晟生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Patent CN106539697A discloses an anti-caries and anti-sensitivity polishing paste and its preparation method. Ammonium hexafluorosilicate is added to the polishing paste. It is fluoride, which not only has certain toxic and side effects, but also excessive use of fluoride can cause dental fluorosis and skeletal fluorosis, and the remineralization of early caries by fluoride is limited to the surface of the lesion, and fluoride prevents deep tooth detachment. Remineralization of mineral tissue, leading to the problem that the anti-sensitivity effect is not long-lasting

Method used

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  • Anti-allergy polishing paste containing potassium calcium phosphosilicate bioglass
  • Anti-allergy polishing paste containing potassium calcium phosphosilicate bioglass
  • Anti-allergy polishing paste containing potassium calcium phosphosilicate bioglass

Examples

Experimental program
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Effect test

preparation example 1

[0040] Preparation example 1 provides a kind of potassium calcium phosphosilicate bioglass, and its preparation steps are:

[0041] Mix 50g of nano-silica, 20g of potassium dihydrogen phosphate, 10g of potassium carbonate and 30g of calcium oxide, stir evenly and put them into a high-temperature melting furnace, heat to 1550°C for a high-temperature liquid-phase chemical reaction for 6 hours to obtain potassium calcium phosphosilicate, Calcium potassium phosphosilicate is cooled to 25°C, and then the cooled calcium calcium phosphosilicate is pulverized into 5 μm particles using an ultrafine pulverizer to obtain calcium calcium phosphosilicate bioglass;

[0042] The chemical reaction formula of the synthesis of potassium calcium phosphosilicate by described nano silicon dioxide, potassium dihydrogen phosphate, potassium carbonate and calcium oxide is:

[0043] SiO 2 +KH 2 PO 4 +K 2 CO 3 +CaO=KCaPSiO 6 +CO 2 ↑+K 2 O↑+H 2 O↑;

[0044] Wherein, the high-temperature melti...

Embodiment 1

[0048] Embodiments 1-26 provide an anti-sensitivity polishing paste containing calcium calcium phosphosilicate bioglass, which will be described below by taking Embodiment 1 as an example.

[0049] The anti-sensitive polishing paste containing calcium calcium phosphosilicate bioglass that embodiment 1 provides, its preparation steps are:

[0050] Stir 30g humectant, 2g thickener, 3g amino acid surfactant and 2g betaine evenly, then add 2.5g calcium calcium phosphosilicate bioglass and 5g silicon dioxide, stir, grind and knead until fully mixed , and then evacuated until the vacuum degree reaches 0.096MPa, and finally aged for 180min to obtain an anti-sensitive polishing paste containing calcium calcium phosphosilicate bioglass;

[0051] Wherein, the humectant is food grade glycerin;

[0052] Described thickening agent is food grade carbomer;

[0053] The amino acid surfactant is sodium cocoyl glutamate (CAS No. 68187-32-6);

[0054] The betaine is betaine monohydrate (CAS N...

Embodiment 2-5

[0057] Examples 2-5 are the same as Example 1, except that the quality of the raw materials for the preparation of the anti-sensitive polishing paste containing calcium calcium phosphosilicate bioglass is different in quality, see Table 2 for details.

[0058] Table 2

[0059] components Example 1 Example 2 Example 3 Example 4 Example 5 moisturizer 30g 50g 40g 40g 40g thickener 2g 4g 3g 3g 3g amino acid surfactant 3g 5g 4g 4g 4g betaine 2g 4g 3g 3g 3g Potassium calcium phosphosilicate bioglass 2.5g 7.5g 5g 4g 5g silica 5g 15g 10g 8g 12g

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Abstract

An anti-allergy polishing paste containing potassium calcium phosphosilicate bioglass is prepared from the following raw material components in parts by weight: 2.5 to 7.5 parts of the potassium calcium phosphosilicate bioglass, 5 to 15 parts of silicon dioxide, 30 to 50 parts of a humectant, 2 to 4 parts of a thickening agent, 3 to 5 parts of an amino acid surfactant and 2 to 4 parts of betaine. According to the prepared anti-allergy polishing paste containing the potassium calcium phosphosilicate bioglass, the potassium calcium phosphosilicate bioglass is added, the polishing paste is free of toxic and side effects and high in biological safety, the remineralization promoting effect of the potassium calcium phosphosilicate bioglass is good, caries bacteria and dental plaque bacteria can be inhibited, enamel can be strengthened, and compared with traditional potassium nitrate, sodium fluoride and other traditional anti-allergy components, the potassium calcium phosphosilicate bioglass is higher in safety and has a remarkable effect on resisting dentin hypersensitivity; meanwhile, the potassium calcium phosphosilicate bioglass, the amino acid surfactant and the betaine act together, so that the anti-allergy effect durability and stability of the anti-allergy polishing paste are improved.

Description

technical field [0001] The application relates to dental polishing technology, in particular to an anti-sensitive polishing paste containing calcium calcium phosphosilicate bioglass. Background technique [0002] The residues of tobacco, tea, coffee, colored food and other substances in daily life are easy to deposit on the tooth surface through the organic film of salivary protein on the tooth surface. Yellowing or even blackening, forming exogenous stains and stains on teeth, which not only affects oral hygiene, but also affects the appearance of teeth. In recent years, with the development of the economy and the improvement of people's living standards, people have higher and higher requirements for oral hygiene and health. [0003] Traditional oral care products (such as toothpaste, mouthwash, etc.) can no longer meet consumers' needs for oral health care. Regular cleaning of teeth is an important means of protecting teeth. Failure to clean teeth for a long time will c...

Claims

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Application Information

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IPC IPC(8): A61K8/25A61K8/44A61K8/73A61K8/81A61K8/34A61K8/21A61Q11/00A61P1/02
CPCA61K8/25A61K8/44A61K8/442A61K8/73A61K8/8147A61K8/345A61K8/21A61Q11/00A61P1/02A61K2800/48
Inventor 徐阳波
Owner 佛山市诺晟生物科技有限公司
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