Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A preparation method of photothermal antibacterial near-infrared bimetallic nanoparticles

A bimetallic nanometer and near-infrared technology, applied in botany equipment and methods, chemicals for biological control, disinfection, etc., can solve the problems of drug resistance, side effects of antibacterial materials, large antibacterial dose, etc., and achieve improved sterilization The effect of activity, strong light-to-heat conversion ability, and good bactericidal performance

Active Publication Date: 2022-04-15
NANJING NORMAL UNIVERSITY +1
View PDF12 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Purpose of the invention: Aiming at the problems existing in the existing metal antibacterial materials, the present invention prepares a kind of photothermal antibacterial near-infrared bimetallic nanoparticles (abbreviated as Au@CuO). The preparation method of the near-infrared bimetallic nanoparticles prepared by the present invention is simple and It does not require expensive instruments, and can make up for the gaps in this technology and the gaps in multiple fields at the same time; it solves: 1. The problem of a large antibacterial dose required for a single gold nanoparticle; 2. The drug resistance that occurs during the treatment of bacterial infections 3. Problems of side effects caused by traditional antibacterial materials

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A preparation method of photothermal antibacterial near-infrared bimetallic nanoparticles
  • A preparation method of photothermal antibacterial near-infrared bimetallic nanoparticles
  • A preparation method of photothermal antibacterial near-infrared bimetallic nanoparticles

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] A method for preparing photothermal antibacterial near-infrared bimetallic nanoparticles, comprising the following steps:

[0041] Step 1, weigh 0.03 g of chloroauric acid, 0.026 g of copper chloride, 0.25 g of glucose and 0.1 g of hexadecylamine in a 50 mL scintillation vial, add 25 mL of ultrapure water, and stir at room temperature at 600 r / min for 18 h.

[0042] Step 2, transfer the scintillation vial to an oil bath, and react for 0.5 h at 100 °C, stirring at 600 r / min.

[0043] Step 3, after the reaction is completed, the product to be synthesized is cooled to 25 °C.

[0044] In step 4, the obtained brown-black solution was placed in a centrifuge and centrifuged at 10,000 rpm for 8 min, and 25 mL of deionized water was added to the obtained precipitate, and it was dispersed by ultrasonication at room temperature for 10 min.

[0045] Step 5, put the above solution in a centrifuge and centrifuge at 10,000 rpm for 8 min. After repeating three times, add 25 mL of eth...

Embodiment 2

[0052] A method for preparing photothermal antibacterial near-infrared bimetallic nanoparticles, comprising the following steps:

[0053] Step 1, weigh 0.03 g of chloroauric acid, 0.026 g of copper chloride, 0.25 g of glucose and 0.45 g of hexadecylamine in a 50 mL scintillation vial, add 25 mL of ultrapure water, and stir at room temperature at 600 r / min for 18 h.

[0054] Step 2, transfer the scintillation vial to an oil bath, and react for 0.5 h at 100 °C, stirring at 600 r / min.

[0055] Step 3, after the reaction is completed, the product to be synthesized is cooled to 25 °C.

[0056] In step 4, the obtained brown-black solution was placed in a centrifuge and centrifuged at 10,000 rpm for 8 min, and 25 mL of deionized water was added to the obtained precipitate, and it was dispersed by ultrasonication at room temperature for 10 min.

[0057] Step 5, put the above solution in a centrifuge and centrifuge at 10,000 rpm for 8 min. After repeating three times, add 25 mL of et...

Embodiment 3

[0062] A method for preparing photothermal antibacterial near-infrared bimetallic nanoparticles, comprising the following steps:

[0063] Step 1, weigh 0.03 g of chloroauric acid, 0.026 g of copper chloride, 0.25 g of glucose and 0.35 g of hexadecylamine in a 50 mL scintillation vial, add 25 mL of ultrapure water, and stir at room temperature at 600 r / min for 18 h.

[0064] Step 2, transfer the scintillation vial to an oil bath, and react for 0.5 h at 100 °C, stirring at 600 r / min.

[0065] Step 3, after the reaction is completed, the product to be synthesized is cooled to 25 °C.

[0066] In step 4, the obtained brown-black solution was placed in a centrifuge and centrifuged at 10,000 rpm for 8 min, and 25 mL of deionized water was added to the obtained precipitate, and it was dispersed by ultrasonication at room temperature for 10 min.

[0067] Step 5, put the above solution in a centrifuge and centrifuge at 10,000 rpm for 8 min. After repeating three times, add 25 mL of et...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle diameteraaaaaaaaaa
Login to View More

Abstract

The invention discloses a preparation method of photothermal antibacterial near-infrared bimetallic nanoparticles. The preparation method comprises: adding chloroauric acid, copper chloride, long-chain organic amine and reducing agent into ultrapure water and stirring overnight, and Heating in an oil bath, cooling the reaction product, centrifuging it, dissolving the resulting precipitate in deionized water, washing with deionized water and ethanol three to four times, and drying in vacuum to obtain near-infrared bimetallic nanoparticles . The invention obtains near-infrared bimetallic nanoparticles. Compared with other nanoparticles, it has a certain antibacterial activity, and can also realize photothermal sterilization under near-infrared light irradiation. The combination of the two shows high-efficiency antibacterial activity. , can be widely used in biological materials, medical devices, wound antibacterial disinfection, etc., and reduces the risk of bacterial drug resistance, and has broad application prospects in the field of antibacterial materials in the future.

Description

technical field [0001] The invention belongs to the technical field of antibacterial metal nanomaterials, and in particular relates to a preparation method of photothermal antibacterial near-infrared bimetallic nanoparticles. Background technique [0002] Bacterial infections have become a major threat to human health worldwide, and in response to this challenge, antibiotics such as penicillin and colistin have been developed to treat bacterial infections. However, the long-term use and overuse of traditional antibiotics has contributed to the emergence of multidrug-resistant bacteria, while threatening public health through multiple channels such as food, water and livestock. In order to solve this problem, antibacterial biomaterials have gradually come into our field of vision. Antibacterial biomaterials are new types of biomaterials that have a greater ability to kill or inhibit microorganisms through physical and chemical actions. According to the different effective an...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A01N59/20A01N59/16A01P1/00A61L2/08
CPCA01N59/20A01N59/16A61L2/085A61L2/08A61L2202/24A61L2202/26
Inventor 周宁琳刘奕含沈健楚晓红张盼宋秋娴王玉丽冯文立石绍泽徐旺
Owner NANJING NORMAL UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com