68 results about "Bimetallic nanoparticle" patented technology

The invention provides a nano-drug based on atomic layer deposition and a preparation method of the nano-drug, mesoporous silica is taken as a carrier, bimetallic nanoparticles are precisely deposited through ALD, and chemotherapeutic drugs and antibacterial components are loaded by combining amination and targeted PEG modification, so that the following functions are realized: (1) H2O2 in a tumor microenvironment is catalyzed to generate reactive oxygen species (ROS); removing fusobacterium nucleatum and damaging a biological membrane of the fusobacterium nucleatum; (2) GSH is consumed through Fenton reaction, and tumor drug resistance is reversed; and (3) the drug is released in pH response, and tumor cells are accurately killed. The invention further provides application of the nano-drug based on atomic layer deposition in treatment of related drug-resistant colorectal cancer induced by fusobacterium nucleatum, the process is controllable, the biocompatibility is excellent, the treatment effect on the drug-resistant colorectal cancer is remarkably improved, and the nano-drug has wide clinical application prospects.

The invention discloses a preparation method and application of a zinc-bromine flow battery positive electrode material, and belongs to the field of zinc-bromine flow batteries. The preparation method comprises the following steps: firstly, cleaning and activating a carbon-based three-dimensional conductive network substrate by adopting plasmas, performing oxygen / argon plasma etching, and performing chemical vapor deposition on carbon to prepare three-dimensional porous carbon; then growing a metal oxide nanocrystalline array on the three-dimensional porous carbon by a hydrothermal method, and carrying out ammonia gas calcination to convert the metal oxide nanocrystalline array into a metal nitride nanocrystalline array; then preparing an electro-deposition solution containing tin bismuth salt and an aniline-bromine source polymerization solution, and constructing Sn-Bi bimetallic nanoparticles and a polyaniline-bromine complex layer on the metal nitride nanocrystalline array / three-dimensional porous carbon precursor through electro-deposition and electro-polymerization in sequence to finally prepare the high-performance zinc-bromine battery positive electrode material. The positive electrode material has high conductivity, excellent Br2 / Br <-> catalytic activity and structural stability, and the coulombic efficiency, the voltage efficiency and the energy efficiency of the battery are remarkably improved.

The invention discloses a zeolite / silver / copper ternary inorganic nano antibacterial and antiviral material as well as a preparation method and application thereof. The preparation method comprises the following steps: preparing a mixed solution of a template agent and an anchoring agent, loading a metal precursor, adding a silicon source, performing hydrothermal crystallization and performing post-treatment. According to the zeolite / silver / copper ternary inorganic nano antibacterial and antiviral material disclosed by the invention, Ag-Cu bimetallic nanoparticles are formed by introducing copper nitrate and silver together, so that the catalytic activity, selectivity and stability of the zeolite / silver / copper ternary inorganic nano antibacterial and antiviral material are remarkably enhanced, and the dosage of noble metal silver can be reduced.

The invention relates to a preparation method of a carbon-based gold-containing bimetallic catalyst. The specific method comprises the following steps: carrying out secondary doping on eigenstate polyaniline, carrying out high-temperature pyrolysis in an inert atmosphere to obtain a heteroatom-doped carbon-based carrier, and changing the variety, the content and the distribution of heteroatoms on the carbon surface of the carrier by adjusting the variety and the content of acid. And preparing gold-containing bimetallic nanoparticles by using a colloid method, and depositing bimetallic particles by virtue of adsorption of the carbon carrier and bimetallic to obtain the carbon-based gold-containing bimetallic catalyst. Wherein the doping element can anchor and disperse the noble metal, and the introduced second metal can improve the hydrogenation activity of the catalyst. The catalyst is simple in preparation process, good in activity, excellent in selectivity and excellent in cycling stability, is particularly suitable for a reaction for preparing 4-chloroaniline through catalytic hydrogenation of 4-chloronitrobenzene, and has good application potential.

The invention provides Ni-Fe / ZrO2 bimetallic nanoparticles as well as a preparation method and application thereof, and belongs to the technical field of catalysts. The preparation method comprises the following steps: firstly, preparing ZrO2 loaded with NiO, FeO and Fe2O3 by adopting an impregnation method, and then carrying out reduction treatment by adopting a reducing atmosphere to prepare the Ni-Fe / ZrO2 bimetallic nanoparticles. In the prepared bimetallic nanoparticles, nickel and iron are combined and loaded on zirconium dioxide, so that the Ni and Fe nanoparticles are anchored through interaction of strong metal and a carrier, the catalytic performance is remarkably improved, a multifunctional catalyst is achieved, subcritical water oxidation of Fe, in-situ production of hydrogen and promotion of the hydrodeoxygenation process of cellulose by Ni can be achieved, and the hydrodeoxygenation efficiency of cellulose is improved. Meanwhile, the surface of the ZrO2 carrier has acidic and alkaline sites, so that the ZrO2 carrier can interact with active components with different properties to promote continuous forward proceeding of the reaction, and efficient conversion of cellulose to 2, 5-hexanedione under mild reaction conditions is realized.

The invention discloses a hexachlorophenol electrochemical sensor built based on NiFe-coated C / MoO3 and a preparation method and application thereof.The hexachlorophenol electrochemical sensor comprises a working electrode, an auxiliary electrode and a reference electrode, the working electrode is a NiFe-coated C / MoO3 modified electrode and is composed of a glassy carbon electrode and a NiFe-coated C / MoO3 composite material modified on the glassy carbon electrode, the auxiliary electrode is a NiFe-coated C / MoO3 modified electrode, and the reference electrode is a NiFe-coated C / MoO3 modified electrode. The NiFe (at) C / MoO3 composite material comprises a NiFe (at) C framework and MoO3 loaded on the NiFe (at) C framework, and the NiFe (at) C framework is formed by embedding NiFe bimetal nanoparticles into a porous carbon framework. The preparation method comprises the steps of synthesis of MoO3, synthesis of NiFe C, preparation of the modified electrode and preparation of the electrochemical sensor. The hexachlorophenol electrochemical sensor disclosed by the invention can be used for direct electrochemical detection without derivatization, and is high in selectivity, portable at low cost, ultrahigh in sensitivity and good in application prospect.

The invention relates to a preparation method of 1, 1, 1, 2, 3-pentachloropropane and a catalyst, and the 1, 1, 1, 2, 3-pentachloropropane is obtained by carrying out chlorination reaction on 1, 1, 1, 3-tetrachloropropane and chlorine in the presence of a loaded zero-valent bimetallic nanoparticle catalyst and a cocatalyst. The zero-valent bimetallic nanoparticle loaded catalyst comprises a carrier and an active component loaded on the carrier, the active component comprises zero-valent Sb-Al nanoparticles or Sb-Fe nanoparticles, and the cocatalyst comprises alkyl phosphine, aryl phosphine or alkyl aryl phosphine. On one hand, the oxidation inactivation and agglomeration phenomena of the catalyst are avoided, the surface area of the active component of the catalyst is increased, and the reaction is facilitated; on the other hand, the catalytic activity of the bimetallic nanoparticle catalyst is improved by using the cocatalyst, the reaction activation energy is reduced, and the reaction rate and the reaction selectivity are improved.

A CuCo catalyst, a preparation method and a use for preparing lower alcohols from syngas. The CuCo catalyst uses zinc-aluminum composite oxide Zn(Al)O as a carrier, and bimetallic nanoparticles of Cu and Co are loaded on the surface of the carrier. The Co loading of the CuCo catalyst is 0.5 wt% - 22 wt%, and the Cu loading is 0.5 wt% - 22 wt%. By regulating the synthesis method of the hydrotalcite precursor and controlling the process conditions during the preparation, a CuCo bimetallic catalyst with controllable structure is obtained. Due to the characteristic of uniform distribution of dual active sites, the catalyst can achieve high selectivity, activity and stability when used for preparing C 2+ OH from syngas and has good application prospects.

The invention provides a composite catalyst for supercritical water gasification hydrogen production and a preparation method and application thereof, and relates to the technical field of organic solid waste recycling, the composite catalyst comprises a carrier, an active component and an auxiliary agent; the carrier is prepared from a ZrO2 mesoporous material co-doped with Ce and La; the active component comprises Ni-Co bimetallic nanoparticles, and the Ni-Co bimetallic nanoparticles are subjected to vulcanization treatment to form a core-shell structure in which Ni-Co metal is wrapped by sulfur; and the auxiliary agent comprises MoO3. According to the composite catalyst, a Ce-La-ZrO2 mesoporous material serves as a carrier, Ni-Co bimetallic nanoparticles serve as an active component, a core-shell structure (NiCo at S) is formed after vulcanization treatment, the surface of the core-shell structure is covered with a layer of sulfur atoms, carbon deposition can be effectively inhibited, the chlorine poisoning resistance of the catalyst is enhanced through the added MoO3 auxiliary, and the service life of the catalyst is prolonged.

The invention relates to a preparation method of 1, 1, 1, 3, 3-pentachloropropane and a catalyst, in the presence of a loaded zero-valent bimetallic nanoparticle catalyst and a cocatalyst, carbon tetrachloride and vinyl chloride are subjected to an addition reaction to obtain 1, 1, 1, 3, 3-pentachloropropane, the zero-valent bimetallic nanoparticle loaded catalyst comprises a carrier and an active component loaded on the carrier; the active component is prepared from zero-valent Pd-Fe nano particles or Cu-Fe nano particles; the cocatalyst comprises boric acid ester or acetyl citrate. The preparation method of 1, 1, 1, 3, 3-pentachloropropane can effectively avoid easy agglomeration when only Fe powder is used as a catalyst, the specific surface area of the iron powder is increased, the reaction is promoted, meanwhile, the used cocatalyst is a nitrogen-free and phosphorus-free catalyst, emission of three wastes containing nitrogen and phosphorus is avoided, and the preparation method is environment-friendly.

The invention provides a preparation method of a graphdiyne-loaded bimetallic nano material for VOCs adsorption. The preparation method comprises the following steps: S1, synthesizing a large-area and low-defect graphdiyne film by using an in-situ interface growth method; and S2, loading bimetallic nanoparticles on the surface of graphdiyne by adopting a co-impregnation-step reduction method. Meanwhile, the invention provides the graphdiyne-loaded bimetallic nano-material for VOCs adsorption, the graphdiyne-loaded bimetallic nano-material is prepared by adopting the preparation method, the graphdiyne-loaded bimetallic nano-material comprises Cu-Ag alloy nano-particles and Cu + active sites, Cu + accounts for 90% or above of the total copper content, and the nano-particles are anchored to the graphdiyne ring through a Cu-O-C equivalent key; in the aspects of stability and regeneration performance, after 20 times of adsorption-desorption cycle tests, the material capacity retention rate is gt; 90%.

The application discloses a method for activating persulfate for improving the degradation performance of organic pollutants based on a flow-through electrocatalytic membrane, which comprises two steps of preparing a boron nitride electrocatalytic membrane loaded with bimetallic nanoparticles and carrying out a flow-through degradation reaction. Compared with a traditional mode, the flow-through mode provided by the application realizes effective coupling of a membrane catalytic system and a conventional electro-activated persulfate system, breaks through the limitation of low mass transfer efficiency, significantly improves the utilization rate of persulfate, and thus improves the degradation efficiency of organic pollutants. The flow-through reactor provided by the application has the advantages of simple structure, strong operability, low catalyst loss and good stability, has a wide industrial application prospect, and provides an efficient, economical and sustainable solution for the degradation of organic pollutants.

The invention relates to a biological nano imbibition oil-displacing agent and a preparation method thereof, and the biological nano imbibition oil-displacing agent comprises the following components in percentage by weight: 40-55wt% of dispersing agent; 20 to 35 wt% of first modified metal nanoparticles; 20 to 35 wt% of second modified metal nanoparticles; the dispersing agent is brevibacillus borsteri fermentation cell removal liquid; the first modified metal nanoparticles are biosurfactant modified metal nanoparticles; the second modified metal nanoparticles are plant extract modified bimetallic nanoparticles. The oil-displacing agent provided by the invention can reduce interfacial tension and capillary force, realizes the effect of efficiently stripping crude oil, and has important significance and economic value for the development efficiency of medium-low permeability reservoirs.

The invention belongs to the technical field of catalysts, and particularly discloses a bimetallic catalyst of a core-shell structure and a preparation method and application thereof.The bimetallic catalyst of the core-shell structure comprises an inner core and an outer shell, the inner core comprises a molecular sieve serving as a carrier and bimetallic nano-particles loaded on the molecular sieve, and the outer shell comprises the molecular sieve and bimetallic nano-particles loaded on the molecular sieve; the shell is a biochar shell coating the inner core, the bimetallic nanoparticles are composed of nano-sized Ni and a second metal M, and the second metal M is one of Mo, W, Co or Ti. The bimetallic catalyst with the core-shell structure provided by the invention has the advantages of stable structure, low cost, high activity and high selectivity, and the preparation method is simple.

The invention discloses a polyelectrolyte multilayer film loaded gold-palladium bimetallic nanoparticle catalyst, which is characterized in that cationic polyelectrolyte poly (diallyldimethylammonium chloride) PDDA and anionic polyelectrolyte sodium polystyrenesulfonate (PSS) are used as construction materials, a layer-by-layer self-assembly technology is adopted to prepare a polyelectrolyte multilayer film, and the polyelectrolyte multilayer film is marked as (PDDA / PSS) n + 0.5, and firstly loading gold nanoparticles on the multilayer film through an ion exchange-in-situ reduction method, and then loading palladium nanoparticles on the multilayer film to obtain the catalyst (PDDA / PSS) (n + 0.5 / a) AubPd for catalyzing the degradation of p-nitrophenol. According to the polyelectrolyte multilayer film loaded gold-palladium bimetallic nanoparticle catalyst disclosed by the invention, by selecting and designing the material and the layer number of the multilayer film carrier and the proportion of gold and palladium bimetallic, the synergistic catalysis of the polyelectrolyte film and the gold-palladium bimetallic nanoparticles is exerted; the catalytic efficiency and the degradation effect of the catalyst in the p-nitrophenol degradation process are obviously improved.

The invention belongs to the field of deep processing of grease, and particularly relates to a lipase immobilization method based on a bimetallic nanoparticle and chitosan composite material. The prepared nano hybrid material is large in specific surface area, high in surface activity, easy to modify and capable of providing more binding sites for enzyme and improving the immobilization efficiency and catalytic performance. According to the preparation method provided by the invention, the metal nanoparticles are added, so that the mechanical strength of the lipase can be enhanced, and the catalytic efficiency and the stability of the lipase can be further improved by adjusting the size, the shape and the surface modification of the nanoparticles. In addition, through compounding of the nanoparticles and the organic material, the flexibility and adjustability of the carrier material can be improved, and a nano hybrid material with mechanical properties and biological compatibility is formed. Chitosan is used as a biodegradable polysaccharide organic material, has rich amino groups and hydroxyl groups, can provide multiple active binding sites for enzyme, and can form a composite carrier material with high mechanical strength and thermal stability after being compounded with metal nanoparticles.

This invention belongs to the field of biosensing technology, specifically relating to a modified carbon fiber electrode for detecting dopamine, its preparation method, and its application. The modified carbon fiber electrode comprises a carbon fiber electrode onto which gold-platinum bimetallic nanoparticles and polydopamine are sequentially modified. The preparation method specifically includes: firstly, modifying the surface of activated carbon fiber filaments with chloroauric acid and sodium citrate to obtain Au@CF; then, modifying the Au@CF surface with ascorbic acid and chloroplatinic acid to obtain platinum nanoparticles, obtaining Au / Pt@CF; finally, immersing the Au / Pt@CF in a dopamine solution to coat the Au / Pt@CF surface with polydopamine, obtaining PDA@Au / Pt@CF. This electrode has advantages such as high sensitivity, low detection limit, strong anti-interference ability, good biocompatibility, and high mechanical stability, making it suitable for dynamic monitoring of dopamine in the living brain.

This invention discloses a bimetallic nanoparticle photocatalytic hydrogen evolution catalyst and its preparation method, relating to the field of photocatalytic materials technology. The bimetallic nanoparticle photocatalytic hydrogen evolution catalyst is composed of a potassium-modified heterojunction composite support, iron nitrate nonahydrate, nickel nitrate hexahydrate, and citric acid monohydrate. The iron-nickel bimetallic nanoparticles are highly dispersed and tightly loaded on the potassium-modified heterojunction composite support, providing abundant catalytic active sites. The tight combination between the two ensures that photogenerated electrons can rapidly flow from the support to the metal, improving catalytic efficiency. Furthermore, through physical confinement effects and strong interactions between the metal and the support, the migration and aggregation of nanoparticles are effectively suppressed. In addition, the zero-valence or low-valence state of the metal active centers is maintained, inhibiting their oxidative deactivation, thereby significantly improving the stability of the catalyst.

The invention discloses a nickel-cobalt bimetallic nanoparticle material for synthesizing tetrahydrofurfuryl alcohol through full hydrogenation as well as a preparation method and application of the nickel-cobalt bimetallic nanoparticle material. The method comprises the following steps: dissolving nickel acetate tetrahydrate and cobalt acetate tetrahydrate in absolute ethyl alcohol, carrying out ultrasonic treatment, adding an ethanol solution in which polyvinylpyrrolidone is dissolved, carrying out ultrasonic treatment, putting into a preheated oil bath pan, standing, refluxing, centrifuging, and taking precipitate, so as to obtain NiCo-precursor; the preparation method comprises the following steps: adding NiCo-precursor and dopamine hydrochloride into an ethanol solution of tris (hydroxymethyl) aminomethane, putting into an oil bath pan, uniformly stirring, centrifuging, washing and drying to obtain NiCo (at) PDA; and calcining in an inert atmosphere to obtain the catalyst. The nickel-cobalt bimetallic nanoparticle material is simple in preparation process, mild in reaction condition, high in catalyst activity, easy to separate and good in cycling stability, and is expected to show good application potential in industrial application.

The invention relates to a catalyst for one-step production of tetrahydrofuran from furfural, which takes a zeolite molecular sieve as a carrier, and platinum-palladium bimetallic nanoparticles or atomic clusters are confined in internal ducts or cavities of the zeolite molecular sieve; the total loading amount of platinum and palladium metal in the catalyst accounts for 0.01-2.0 wt.% of the total mass of the catalyst. Platinum accounts for 0.1-50% of the total atomic mass of platinum and palladium. The catalyst is a zeolite-encapsulated platinum-palladium catalyst which is stable in structure and high in metal dispersity, has monatomic alloy characteristics, is used in a catalytic reaction for one-step production of tetrahydrofuran from furfural, and is good in catalytic performance.

The present invention relates to a magnetic fish scale-based biochar and a preparation method thereof, as well as its application in degrading antibiotic wastewater. Cheap discarded fish scales are used as raw materials, which are modified by decalcification, crushing, and activation using an activator transition metal acetate. After freeze-drying, the pore structure is optimized by high-temperature pyrolysis to form a multi-activation site catalyst with surface-loaded bimetallic nanoparticles. The rapid electron transfer effect between carbon and transition metals is utilized to produce a large amount of active substances, thereby obtaining magnetic fish scale-based biochar with a high specific surface area and high saturation magnetization. The preparation method has simple and easy steps, low raw material cost, short production cycle, easy control of production process conditions, conventional equipment required, strong practicality and operability, and can be promoted and applied in large-scale industry. The application of the modified magnetic fish scale-based biochar in the treatment of antibiotic wastewater can effectively remove antibiotics in water and reduce the toxicity of wastewater.

The invention relates to the technical field of catalytic oxidation carbonylation, in particular to a catalyst and a preparation method and application thereof. The invention provides a catalyst. The catalyst comprises nitrogen doped carbon and CoCu bimetallic nanoparticles dispersed in the nitrogen doped carbon. The catalyst has high activity, high selectivity and long service life.

The invention discloses a copper-cobalt-loaded ferric oxide composite photocatalyst, a preparation method and application of the copper-cobalt-loaded ferric oxide composite photocatalyst in hydrogen production by photocatalytic ammonia borane hydrolysis, and belongs to the technical field of photocatalysts. The composite photocatalyst (CuxCoy-alpham-gamman-Fe2O3-R, m + n = 100, x + y = 100, and both x and y are not 0) takes Fe2O3 as a core and copper-cobalt bimetallic nanoparticles reduced by sodium borohydride as an active component, and efficient hydrogen production by ammonia borane hydrolysis is realized through a photocatalysis synergistic effect. The method is simple in synthesis step, small in pollution, low in equipment requirement, mild in reaction condition and easy to implement. Under illumination, strong reducing electrons are generated on the surface of the catalyst, the hydrolysis activation energy is remarkably reduced, the hydrogen production rate reaches 21875 mL.min <-1 >. G <-1 > and is increased by 258% compared with that without illumination, the hydrogen yield can reach 100%, and the activity of the composite photocatalyst is not attenuated after 10 times of circulation after magnetic recovery.

The invention discloses a photochemical controllable deposition method based on copper-silver bimetallic nanoparticles, and relates to the technical field of nano material preparation, and the photochemical controllable deposition method comprises the following steps: constructing a light excitation-molecular conformation regulation-acoustic streaming diffusion three-dimensional coupling system by utilizing the cooperative regulation of a light response biomolecule dynamic template and an acoustic oscillation microbubble field; the photoresponse biomolecule dynamic template is used for regulating and controlling an atomic-scale interface structure, and the acoustic oscillation microbubble field is used for homogenizing a metal ion diffusion environment; through excitation of dual-wavelength circularly polarized light, silver core formation, copper atom spiral deposition and three-dimensional nanowire array assembly are realized in sequence; in the invention, through cooperation of the photoresponse template and the acoustic microbubble field and excitation of dual-wavelength circularly polarized light, the problems of heavy pollution, difficulty in interface regulation and control and photodeposition three-dimensional construction bottleneck of a traditional wet chemical method are solved, and atomic order of a bimetallic interface, improvement of deposition uniformity and controllable assembly of the vertical alignment nanowire array are realized; and the method has the green process advantages of low pollution and no strict template removal.

The application belongs to the technical field of drug delivery carrier, and particularly relates to a dual-metal nanodot-oncolytic virus intravenous delivery system and a preparation method and application thereof in tumor immunotherapy. The oncolytic adenovirus is used as raw material, and the dual-metal nanodot-adenovirus chimera is constructed by using the covalent force of 4-maleimide butyric acid-N-succinimidyl ester. The preparation performance, cytotoxicity, action mechanism, in-vivo anti-tumor effect, anti-tumor immunity, anti-tumor recurrence and anti-tumor metastasis effect of the chimera are evaluated. The preparation process is simple, the prepared dual-metal nanodot-adenovirus chimera has small and uniform particle size, is conducive to enrichment in tumor tissues through the enhanced permeability and retention (EPR) effect, has high drug loading capacity, good safety and can generate high-intensity MRI signals at the tumor site. The designed dual-metal nanodot-adenovirus chimera realizes the integration of tumor diagnosis and treatment.

A hybrid catalytic nanoreactor having selectivity and stability in presence of air is provided for reduction reactions including semi-hydrogenations comprising of light harvesting dendritic plasmonic colloidosomes (DPC) of gold preferably as black gold and co-acting synergistically active catalytic sites of Pt-doped Ru bimetallic nanoparticles for desired significantly special selectivity and air-stability as a plasmonic reduction catalyst favoring plasmon-mediated simultaneous reduction and oxidation of metal active sites for facilitating reduction reactions including semi-hydrogenation activity. Said black gold / RuPt catalyst showcases good efficiency in acetylene semi-hydrogenation, attaining over 90% selectivity with ethene production rate of 320 mmol g−1 h−1 with its stability evident from 100 h of operation with continuous air flow, attributed to the synergy of co-existing metal oxide and metal phases. The catalyst's stability is further enhanced by plasmon-mediated concurrent reduction and oxidation of the active sites, facilitating its end use and applications in chemical industries, petrochemical industries, and applications catalysis.

The invention provides a multi-mode response bimetallic nanoparticle as well as a preparation method and application thereof. The nanoparticle comprises a photosensitive conversion agent, an active pharmaceutical ingredient and a framework material which are sequentially arranged from inside to outside, wherein the mass of the active pharmaceutical ingredient accounts for 1-20% of the mass of the whole nanoparticle, the encapsulation efficiency of the active pharmaceutical ingredient in the encapsulation process is 30-100%, and the particle size of the nanoparticle is 50-3000 nm. The nanoparticles have unique pH and photo-thermal response characteristics, can control smooth release of drugs at tumor sites, have low biotoxicity, do not harm normal tissues and organs of a human body, and can enhance drug activity, reduce adverse side effects and improve biological safety at the same time. Wherein the CZID nanoparticles are high in biological safety and good in anti-tumor effect, and a new way is provided for tumor treatment.

The present application relates to the technical field of biological detection, and particularly relates to a system and a method for detecting oxidized low density lipoprotein. The PLA-HCR metallization system provided by the present application constructs an "AND" logic gate based on a proximity effect, realizes direct recognition and signal amplification of oxLDL complete particles in combination with a hybridization chain reaction, and overcomes the limitation in traditional methods that only rely on indirect reflection of lipoprotein particle concentration between single components; the system uses gold-platinum bimetallic nanoparticles to endow oxLDL particles with high-efficiency exogenous peroxidase catalytic activity, and compared with traditional peroxidase, the enzyme catalytic efficiency is significantly improved, and the system has the ability to directly detect undiluted serum samples, avoiding the cumbersome pretreatment process of traditional ELISA methods. The present application has the characteristics of high specificity, wide detection range and simple operation, and has a wide application prospect in early diagnosis, curative effect monitoring and prognosis evaluation of patients with atherosclerotic cardiovascular disease.

A method for preparing platinum-based lanthanum cobalt oxide catalysts for NO oxidation is disclosed, belonging to the fields of catalytic chemistry and environmental chemistry. PtMn bimetallic nanoparticles are supported on a lanthanum cobalt oxide support, and PtMn / LaCoO3-air + steam and PtMn / LaCoO3-nitrogen + steam catalysts are obtained after hydrothermal treatment. The preparation method is as follows: Platinum acetylacetone and manganese decacarbonyl are simultaneously reduced using an oil-phase reduction method to form PtMn bimetallic nanoparticles. The PtMn nanoparticles are then loaded onto the lanthanum cobalt oxide support using an impregnation method. The loaded catalyst is placed in a tube furnace and calcined at 650℃ for 8 hours in an air or nitrogen atmosphere containing H2O to form a catalyst. The obtained catalyst contains a richer content of active oxygen species and exhibits good catalytic activity for NO oxidation under low-temperature conditions, showing promising application prospects in the field of motor vehicle exhaust pollution control.

The present invention discloses a nitrogen-doped carbon nanofiber membrane anchored with ultrafine Fe-Mn bimetallic nanoparticles for flow-through electro-Fenton degradation of organic pollutants, belonging to the field of organic pollutant degradation. The nitrogen-doped carbon nanofiber membrane anchored with ultrafine Fe-Mn bimetallic nanoparticles is highly connected by nitrogen-doped carbon nanofibers, wherein the Fe-Mn bimetallic crystals are uniformly coated in the form of ultrafine particles in the fibers. Its preparation method comprises the following steps: using FeMn LDHs prepared by reacting a manganese source and an iron source as a metal source, mixing with polyacrylonitrile, and preparing a FeMn LDHs / PAN nanofiber membrane by electrospinning; performing carbonization treatment on the FeMn LDHs / PAN nanofiber membrane to obtain a FeMn / N-CNF nanofiber membrane. The present invention discloses a novel FeMn / N-CNF porous cathode membrane with strong metal-support interaction force, which can be combined with an IrO2 / RuO2-Ti electrode to construct a flow-through electro-Fenton membrane reactor with good anti-scaling ability. It can efficiently and stably purify organic wastewater in a wide pH range and meet the requirements of practical applications.