The invention discloses a simple preparation method of benzothiazole salt ionic liquid and application thereof to organic catalytic synthesis. In the invention, the benzothiazole salt ionic liquid has a novel structure, benzothiazole N-alkyl quaternary ammonium salt is used as cations (alkyl is one of n-C4H9, n-C5H11 and n- C6H13), BF4<-> or PF6<-> is used as anions. In the preparation method, benzothiazole, chloralkane, alkyl bromide and alkali metal salt or ammonium salt which contains the target anions react in one step under a solvent-free condition. In the invention, the one-step method is used for preparing the benzothiazole salt ionic liquid, therefore, the preparation yield is greatly increased, the use of substrates with high toxicity and high price is avoided, the consumption of organic solvents is reduced, the excessive use of a certain reaction component is avoided, the preparation process is simplified and high product yield is ensured. Therefore, the method has god economy and environmental friendliness and is suitable for mass preparation. The benzothiazole salt ionic liquid can be used as a mild, exclusive and efficient catalyst in benzoin condensation and Biginelli condensation and can be recycled and reused many times.