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Method for modifying ZrC coating on surface of intravascular stent

A vascular stent and coating technology, which is applied in the field of ion nitriding modification of ZrC coating on the surface of vascular stents, can solve the problems that the corrosion resistance needs to be improved, the corrosion resistance of bare metal stents cannot be satisfied, and the corrosion resistance can be improved. Effect

Active Publication Date: 2021-06-25
XIANGYA HOSPITAL CENT SOUTH UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Metal materials (medical stainless steel, nickel-titanium memory alloy, etc.) are widely used in the field of vascular stents, but the corrosion resistance of bare metal stents usually cannot meet the complex liquid environment of the human body. Ways to improve the corrosion resistance of metal stent materials, among which ZrC coating is one of many stent coatings
However, the self-corrosion current of the existing ZrC coating for vascular stents is about 2-5μA / cm 2 , this corrosion resistance needs to be improved

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] A modification method of ZrC coating on the surface of vascular stent, comprising the following steps:

[0020] The medical 316L stainless steel is used as the support substrate, and the substrate is pretreated. The pretreatment includes pickling, grinding, cleaning and drying. # and 1200# sandpaper, cleaning with deionized water and ultrasonic assisted cleaning, drying in a protective atmosphere.

[0021] Put the dried substrate into a magnetron sputtering coating machine, pass in argon gas, and carry out plasma bombardment on the substrate.

[0022] Using Zr-7.8wt% graphite composite target as the sputtering source and argon as the working gas, ZrC coating was deposited on the surface of the support substrate, wherein the background vacuum degree was 5×10 -5 Pa, the argon gas flow rate is 50 sccm, the substrate temperature is 180°C, the sputtering pressure is 3.0Pa, and the sputtering power is 80W.

[0023] Put the vascular stent covered with ZrC coating into the io...

Embodiment 2

[0026] A modification method of ZrC coating on the surface of vascular stent, comprising the following steps:

[0027] The medical 316L stainless steel is used as the support substrate, and the substrate is pretreated. The pretreatment includes pickling, grinding, cleaning and drying. # and 1200# sandpaper, cleaning with deionized water and ultrasonic assisted cleaning, drying in a protective atmosphere.

[0028] Put the dried substrate into a magnetron sputtering coating machine, pass in argon gas, and carry out plasma bombardment on the substrate.

[0029] Using Zr-7.8wt% graphite composite target as the sputtering source and argon as the working gas, ZrC coating was deposited on the surface of the support substrate, wherein the background vacuum degree was 5×10 -5 Pa, the argon gas flow rate is 50 sccm, the substrate temperature is 180°C, the sputtering pressure is 3.0Pa, and the sputtering power is 80W.

[0030] Put the ZrC-coated vascular stent into the ion nitriding fu...

Embodiment 3

[0033] A modification method of ZrC coating on the surface of vascular stent, comprising the following steps:

[0034] The medical 316L stainless steel is used as the support substrate, and the substrate is pretreated. The pretreatment includes pickling, grinding, cleaning and drying. # and 1200# sandpaper, cleaning with deionized water and ultrasonic assisted cleaning, drying in a protective atmosphere.

[0035] Put the dried substrate into a magnetron sputtering coating machine, pass in argon gas, and carry out plasma bombardment on the substrate.

[0036] Using Zr-7.8wt% graphite composite target as the sputtering source and argon as the working gas, ZrC coating was deposited on the surface of the support substrate, wherein the background vacuum degree was 5×10 -5 Pa, the argon gas flow rate is 50 sccm, the substrate temperature is 180°C, the sputtering pressure is 3.0Pa, and the sputtering power is 80W.

[0037] Put the vascular stent coated with ZrC into the ion nitridi...

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Abstract

A method for modifying a ZrC coating on the surface of an intravascular stent is characterized in that an element N is introduced into an existing ZrC coating through ion nitriding, then a medical material coating containing Zr, C and N is obtained on the surface layer, the self-corrosion current density of the existing ZrC coating with the self-corrosion current density of about 2-5 [mu] A / cm < 2 > can be reduced to 1.5 [mu] A / cm < 2 > or below, and in addition, in a preferred scheme, the self-corrosion current density can even be reduced to 0.759 [mu] A / cm < 2 >, so that the corrosion resistance of the existing ZrC coating of the intravascular stent is greatly improved.

Description

technical field [0001] The invention relates to a modification method of a ZrC coating, in particular to an ion nitriding modification method of a ZrC coating on the surface of a vascular stent. Background technique [0002] Vascular stent refers to the placement of internal stents in the diseased blood vessel segment to support the stenotic and occluded segment of the blood vessel, reduce the elastic retraction and remodeling of the blood vessel, and maintain the blood flow in the lumen. Peripheral vascular stents, aortic stents, cerebrovascular stents, etc. Metal materials (medical stainless steel, nickel-titanium memory alloy, etc.) are widely used in the field of vascular stents, but the corrosion resistance of bare metal stents usually cannot meet the complex liquid environment of the human body. Ways to improve the corrosion resistance of metal stent materials, among which ZrC coating is one of many stent coatings. However, the self-corrosion current of the existing ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C23C14/35C23C14/06C23C14/58C23C8/36C23C8/38A61L31/08A61L31/02A61L31/14
CPCA61L31/02A61L31/08A61L31/14C23C8/36C23C8/38C23C14/06C23C14/35C23C14/58
Inventor 肖瑶冯乐蒙陈功勤刘国栋刘诗晴
Owner XIANGYA HOSPITAL CENT SOUTH UNIV