Photothermal therapy and temperature monitoring integrated system with replaceable probe

Abstract

The invention discloses a photothermal therapy and temperature monitoring integrated system with a replaceable probe. The system comprises a computer, a spectrometer, a laser light source, a coupler, a laser optical fiber, a temperature measuring optical fiber, a double-beam optical fiber, the probe and a temperature controller, wherein the probe is filled with a photothermal therapy composite material, and is provided with a detachable structure, so that probes of different filling materials can be replaced conveniently; laser is coupled with a temperature measuring optical fiber through a laser optical fiber via the coupler and then is transmitted to the probe through the double-beam optical fiber to excite the photothermal therapy composite material, and excited fluorescence is transmitted to the spectrometer through the double-beam optical fiber and the temperature measuring optical fiber to be subjected to light splitting so as to read the luminous intensity of two fluorescence with different wavelengths; and the computer carries out real-time calculation through a fluorescence intensity ratio method to obtain the real-time temperature of the probe, the power of the laser is controlled through the temperature controller, and therefore the effects of real-time monitoring and real-time temperature control are achieved. The photothermal therapy and temperature monitoring integrated system is small in size, can realize real-time monitoring and control and has the characteristic of modularization, and the laser light source, the optical fiber and the probe can be replaced.

Description

technical field [0001] The invention relates to an integrated system for photothermal treatment and temperature monitoring with replaceable probes. Background technique [0002] With the continuous advancement of modern medical technology, the application of laser therapy technology is gradually widespread. Laser has the characteristics of good monochromaticity, good coherence, good directionality and high brightness. Good directivity means that the laser has a smaller divergence angle during transmission than ordinary light sources, so the energy can be better concentrated in one place, and the high energy of the laser can be used to irradiate the object to make it heat up quickly, thereby changing structure. Therefore, laser has become a new processing and treatment method. The laser is irradiated to the patient's site through an optical fiber, which increases the temperature of the irradiated biological tissue and kills the diseased cells. It is often used in tumor tre...

AI Technical Summary

Problems solved by technology

However, traditional laser hyperthermia has problems such as delay in temperature monitoring, poor heating effect, large volume of treatment devices, toxicity and easy residue of indirect heat conduction substances, etc.

[0003] When the temperature rises above 45°C, the diseased cells will be gradually killed. If the heating rate of the laser is too fast, there will be a delay in temperature monitoring, which may cause damage to normal body cells, resulting in unnecessary secondary damage

The current real-time monitoring temperature probe is too large to enter some parts of the human body for treatment, and the replacement is complicated and the maintainability is low

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