L-borneol-based antibacterial polymer as well as preparation method and application thereof
A technology of L-borneol and polymers, applied in botany equipment and methods, applications, chemicals for biological control, etc., can solve the problems of PDMAEMA’s antibacterial performance to be improved, and achieve convenient follow-up design, excellent antibacterial properties, The effect of long-lasting antibacterial activity
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0062] Preparation of bromo-L-borneol initiator, preparation process reference Figure 6 route, including the following steps:
[0063] Into a 50mL three-necked flask, add Le-borneol (3.054g, 0.0198mol), triethylamine (18.96mL, 0.136mol), 4-methylaminopyridine DMAP (6.0474g, 0.0495mol) and 150ml of anhydrous dichloromethane in sequence , under the protection of nitrogen, stir to fully dissolve; add bromoisobutyryl bromide (12.06ml) to the constant pressure funnel, add the same volume of anhydrous dichloromethane to dilute, and place the three-necked flask in an ice-water bath. Turn on the condensing circulating water, drop bromoisobutyryl bromide to start the reaction for 2 hours, then remove the ice-water bath, and react at room temperature 25°C for 48 hours. After the reaction finished, add a small amount of solvent to scrub the bottle wall, after suction filtration, washing, extraction and drying, 4.743g of bromo-L-borneol initiator was obtained, and the calculated reactio...
Embodiment 2
[0065] Preparation of L-borneol-based polydimethylaminoethyl methacrylate, reference for the preparation process Figure 6 route, including the following steps:
[0066] In the Schlank bottle of 50mL, add bromo-L-borneol initiator (0.3828g, 1.263mmol), dimethylaminoethyl methacrylate (3.193ml, 183945mmol) and pentamethyldiethylenetriamine (0.265ml) successively , 1.263mmol), dissolved in 5ml methanol. Under the environment of nitrogen, put the reaction bottle into liquid nitrogen to freeze until the solution is completely solidified, then turn off the nitrogen and evacuate for 5 minutes, and finally pass in nitrogen, put it in water to completely dissolve the solid, repeat the above freezing and degassing operation three times . Put it into liquid nitrogen again to freeze and solidify, quickly add cuprous bromide powder (0.181g, 1.263mmol) and repeat the deoxygenation operation three times, and place the Schlenk bottle in a 45°C oil bath for 10h. After the reaction, first a...
Embodiment 3
[0068] Preparation of L-borneol-based polydimethylaminoethyl methacrylate, reference for the preparation process Figure 6 route, including the following steps:
[0069] In the Schlank bottle of 50mL, add brominated L-borneol initiator (0.4397g, 1.45mmol), dimethylaminoethyl methacrylate (7.34ml, 43.5mmol) and pentamethyldiethylenetriamine (0.265 ml, 1.45mmol), dissolved in 5ml methanol. Under the environment of nitrogen, put the reaction bottle into liquid nitrogen to freeze until the solution is completely solidified, then turn off the nitrogen and evacuate for 5 minutes, and finally pass in nitrogen, put it in water to completely dissolve the solid, repeat the above freezing and degassing operation three times . Put it into liquid nitrogen again to freeze and solidify, quickly add cuprous bromide powder (0.208g, 1.45mmol) and repeat the deoxygenation operation three times, and place the Schlenk bottle in a 45°C oil bath for 11h. After the reaction was completed, 10 mL of...
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More