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Reagent, kit and detection method for quantitative detection of blood iodine

A quantitative detection and reagent technology, applied in measurement devices, material analysis, instruments and other directions by observing the impact on chemical indicators, can solve the problems of troublesome detection, low accuracy, and high detection cost, and achieve less sampling and accurate High rate and good repeatability

Pending Publication Date: 2021-09-03
长沙塞克陆德医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] For this reason, the present invention provides a kind of reagent, test kit and detection method for blood iodine quantitative detection, in order to solve the detection method detection trouble of prior art, detection cost is high, the defect of low accuracy rate

Method used

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  • Reagent, kit and detection method for quantitative detection of blood iodine
  • Reagent, kit and detection method for quantitative detection of blood iodine
  • Reagent, kit and detection method for quantitative detection of blood iodine

Examples

Experimental program
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Effect test

Embodiment 1

[0076] This embodiment provides a reagent for quantitative detection of blood iodine, which includes

[0077] The first solution comprises 20% ammonium sulfate and 8% isopropanol according to mass percentage, and the balance is water;

[0078] The second solution comprises 4.0% sodium hypochlorite and 3.0% sodium chloride according to mass percentage, and the balance is water;

[0079] The third solution comprises 20% sulfuric acid and 3.0% hydrochloric acid in terms of mass percentage, and the balance is water;

[0080] The fourth solution includes 2.5% sodium chloride and 3.0% sodium arsenite in terms of mass percentage, and the balance is water;

[0081] The fifth solution comprises 3.0% ferrous sulfate, 0.2% o-phenanthroline and 2.0% sulfuric acid according to mass percentage, and the balance is water;

[0082] The sixth solution includes 0.2% cerium ammonium sulfate, 1.0% cerium sulfate and 1.5% sulfuric acid in terms of mass percentage, and the balance is water.

[00...

Embodiment 2

[0107] The difference between this embodiment and Example 1 is that the first solution includes 40% acetonitrile by mass percentage, and the balance is water; the second solution includes 7.0% sodium hypochlorite and 4.0% by mass percentage Sodium chloride, the balance is water; the third solution, according to mass percentage, includes 18% sulfuric acid and 4.0% hydrochloric acid, and the balance is water; the fourth solution, according to mass percentage, includes 2.5% sodium chloride and 5.0% sodium arsenite, the balance is water; the fifth solution, according to mass percentage, includes 2.0% ferrous sulfate, 0.5% o-phenanthroline and 5.0% sulfuric acid, and the balance is water; Sixth solution, according to mass percentage, it includes 0.7% cerium ammonium sulfate, 2.3% cerium sulfate and 3.0% sulfuric acid, and the balance is water. Others are all the same as in Example 1.

[0108] The calculation formula is obtained as y=7.7929x -1.2548 . According to the above calcu...

Embodiment 3

[0110] The difference between this embodiment and Example 1 is that the first solution includes 25% acetonitrile and 10% ethyl acetate in mass percent; or 20% ammonium sulfate and 8% isopropanol in mass percent; the second Solution, comprising mass percentage is 10% sodium hypochlorite and 5% sodium chloride; The third solution, comprising mass percentage is 15% sulfuric acid and 12% hydrochloric acid; The fourth solution, comprising mass percentage is 2% sodium chloride and 1% sodium arsenite; the fifth reagent, including 1.2% ferrous sulfate, 1.2% o-phenanthroline and 5% sulfuric acid in mass percent; the sixth solution, including 0.2% cerium sulfate in mass percent ammonium, 0.5% cerium sulfate and 5% sulfuric acid. Others are all the same as in Example 1.

[0111] The calculation formula is obtained as y=6.4067x -1.2378 . According to the above calculation formula, the reaction time of the first serum to be tested is respectively 37.999s, and the obtained y values ​​are...

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Abstract

The invention discloses a reagent, a kit and a detection method for quantitative detection of blood iodine. The reagent comprises a first composition, wherein the first composition is a combination of acetonitrile and ethyl acetate or a combination of ammonium sulfate and isopropanol; a second composition which is a combination of sodium hypochlorite and sodium chloride; a third composition which is a combination of sulfuric acid and hydrochloric acid; a fourth composition which is a combination of sodium chloride and sodium arsenite; a fifth composition which is a composition of ferrous sulfate, phenanthroline and sulfuric acid; and a sixth composition which is a combination of ceric ammonium sulfate, cerous sulfate and sulfuric acid. According to the reagent and the method for rapidly detecting iodine in serum, the digestion solution is low in acidity, the operation is simple, convenient and rapid, and the method can be synchronously used in combination with detection equipment and is not easily influenced by manual errors of experimenters, so that the experimental result is accurate and stable.

Description

technical field [0001] The invention belongs to the technical field of detection reagents, and in particular relates to a reagent, kit and detection method for quantitative detection of blood iodine. Background technique [0002] Iodine is one of the trace elements necessary to maintain the normal thyroid function of the human body. Too much or too little daily intake can cause thyroid diseases, especially for the growth and development of fetuses and young children. Therefore, the World Health Organization and the United Nations Children's Fund will Urinary iodine is an important indicator for evaluating iodine nutritional status, but urinary iodine is greatly affected by diet, individual urinary iodine values ​​are often unstable, and serum iodine is relatively stable, and will not change greatly due to recent dietary changes , can more accurately reflect the individual's recent iodine nutrition level. [0003] The existing standard serum iodine test method is "WS / T572-20...

Claims

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Application Information

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IPC IPC(8): G01N21/78
CPCG01N21/78G01N2021/775Y02A50/30
Inventor 韩鹃
Owner 长沙塞克陆德医疗科技有限公司
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