Compounding method of collagen and poly-L-lactic acid and compounded preparation

A technology of poly-L-lactic acid and collagen, which is applied in the field of compounding methods and compound preparations of collagen and poly-L-lactic acid, can solve the problems of easy stiffness, redness and swelling at the injection site, difficulty in plastic correction again, and large injection volume, etc., to achieve improvement Self-regulating, integrity-maintaining, permeable effects

Pending Publication Date: 2021-09-21
玉本妍南京医疗科技有限公司
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Problems solved by technology

[0003] In the process of realizing the present invention, the inventor found that the hyaluronic acid used for beauty treatment in the prior art has the following problems: within a few days after injection, the injection site tends to be stiff, red and swollen, and the injection volume is large, the fixity is poor, and it is difficult to form after molding. Plastic correction again, so a compound method and compound preparation of collagen and L-lactic acid are proposed here to solve the above problems

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  • Compounding method of collagen and poly-L-lactic acid and compounded preparation

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[0026] In order to make the technical means, creative features, goals and effects achieved by the present invention easy to understand, the present invention will be further described below in conjunction with specific embodiments.

[0027] In describing the present invention, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", " The orientation or positional relationship indicated by "outside", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the referred device or element must have a specific orientation, so as to Specific orientation configurations and operations, therefore, are not to be construed as limitations on the invention.

[0028] In the description of the present invention, it should be noted that, unless otherwise specified and...

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Abstract

The invention relates to the field of biological medicine, and discloses a compounding method of collagen and poly-L-lactic acid and a compounded preparation, and the compounding method comprises the following steps: step 1, carrying out melt mixing and extrusion granulation on a poly-L-lactic acid raw material on the basis that the mass-to-volume ratio is 1 to obtain poly-L-lactic acid particles with the density of 1.0 g / cm < 3 >; and 2, adding the L-polylactic acid and the thickening agent into the phosphate buffer solution under stirring, and uniformly mixing by adopting an ultrasonic dispersion mode. By compounding the collagen fiber and the L-polylactic acid, the collagen fiber and the L-polylactic acid can act on the skin at the same time, the integrity of stratum corneum moisture and a fiber structure can be effectively maintained, the living environment of skin cells is improved, metabolism of skin tissues is promoted, blood circulation is enhanced, the purpose of moistening the skin is achieved, and the use effect is excellent.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to a method for compounding collagen and poly-L-lactic acid and a compound preparation. Background technique [0002] Hyaluronic acid is hyaluronic acid, which is an acidic mucopolysaccharide. In 1934, Meyer, a professor of ophthalmology at Columbia University in the United States, first isolated the substance from the vitreous humor of the bull's eye. Hyaluronic acid shows its unique molecular structure and physical and chemical properties in the body. A variety of important physiological functions, such as lubricating joints, regulating the permeability of blood vessel walls, regulating the diffusion and operation of proteins, water and electrolytes, promoting wound healing, etc., especially, hyaluronic acid has a special water-retaining effect, which is currently discovered The best moisturizing substance in nature is known as the ideal natural moisturizing factor (Natural moisturizing...

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Application Information

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IPC IPC(8): A61K8/85A61K8/65A61K8/73A61K8/67A61K8/24A61Q19/00
CPCA61K8/85A61K8/65A61K8/735A61K8/673A61K8/24A61Q19/00A61K2800/48
Inventor 王龙陈逸平
Owner 玉本妍南京医疗科技有限公司
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