Microcapsule containing active substance and preparation method thereof

A technology of microcapsules and substances, applied in dairy products, food science, milk formulations, etc., can solve problems such as low stability

Pending Publication Date: 2021-11-02
INNER MONGOLIA MENGNIU DAIRY IND (GRP) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Single-layer microcapsules are the most commonly used form of microcapsules. However, regardless of the bacterial content on the particle surface or the wa

Method used

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  • Microcapsule containing active substance and preparation method thereof
  • Microcapsule containing active substance and preparation method thereof
  • Microcapsule containing active substance and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment L1～3

[0181] Embodiment L1~3 and comparative example thereof

Embodiment L1

[0183] Raw materials (based on 150kg dry microcapsules):

[0184] Ball core: Bacillus coagulans 200g, microcrystalline cellulose 800g, water 1000g.

[0185] Water blocking coating layer solution 1: 288g gliadin, 112g oleic acid, 1200g 75% ethanol.

[0186] Water-blocking coating layer solution 2: 54.4g of gliadin, 12.8g of glycerin, and 252.8g of 75% ethanol.

[0187] Hydrophilic coating layer solution: 110g pectin, 2090g water.

[0188] Preparation:

[0189] Mix Bacillus coagulans powder and microcrystalline cellulose evenly and add them to the wet granulation pot for pre-mixing for 10 minutes.

[0190] Turn on the cutting knife, turn on the peristaltic pump 20-30r / min, use 1000kg of water, and take 30mins. A soft material with a moisture content of 49.7% was obtained.

[0191] Start the granulator, feed the material at a speed of 30 rpm, adjust the extrusion speed to 50 rpm, and add soft material for 60 minutes. The strip-shaped soft material is extruded through the ori...

Embodiment L2

[0200] Raw materials (based on 150kg dry microcapsules):

[0201] Ball core: Bacillus coagulans 200g, microcrystalline cellulose 800g, water 1000g.

[0202] Water blocking coating layer solution 1: 270g prolamin, 105g oleic acid, 1125g 75% ethanol.

[0203] Water-blocking coating layer solution 2: 54.4g of gliadin, 12.8g of glycerin, and 252.8g of 75% ethanol.

[0204] Hydrophilic coating layer solution: 110g pectin, 2090g water.

[0205] Preparation:

[0206] Mix Bacillus coagulans powder and microcrystalline cellulose evenly and add them to the wet granulation pot for pre-mixing for 10 minutes.

[0207] Turn on the cutting knife, turn on the peristaltic pump 20-30r / min, use 1000kg of water, and take 30mins. A soft material with a moisture content of 49.7% was obtained.

[0208] Start the granulator, feed the material at a speed of 30 rpm, adjust the extrusion speed to 50 rpm, and add soft material for 60 minutes. The strip-shaped soft material is extruded through the or...

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Abstract

The invention relates to a microcapsule containing an active substance and a preparation method thereof, in particular to a multilayer microcapsule containing an embedded active substance and a preparation method of the multilayer microcapsule. According to the application, the microcapsule particles are prepared by a method of combining extrusion rolling core making (or centrifugal granulation core making) with fluidized spray coating; the preparation method comprises the following steps: firstly, preparing a primary pellet core by adopting an extrusion spheronization granulation method or a centrifugal granulation method, and then uniformly fluidizing a water-blocking coating layer material and a hydrophilic coating layer material to the surface of the pellet core. The prepared microcapsule particles are safe, free of toxic and side effects, small in particle size, rich in active substances and good in stability under the normal temperature condition, and have a slow release effect.

Description

technical field [0001] The invention relates to a microcapsule containing active substances and a preparation method thereof, in particular to a multilayer microcapsule containing embedded active substances and a preparation method thereof. Background technique [0002] In addition to providing people with energy, satisfying people's hobbies, and providing various components of the human body, many food components also have physiological activities and can regulate the functions of the human body, such as enhancing immunity and preventing diseases. Food scientists and food companies in many countries are paying more and more attention to the research and development of this functional food. [0003] Functional food is very important for improving physical fitness and nutritional intervention for chronic diseases. It covers nutritious food, special medical formula food, special dietary food, health food and functional general food, etc. It is the most market demand and develo...

Claims

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Application Information

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IPC IPC(8): A23P10/30A23L33/00A23C9/13
CPCA23P10/30A23L33/00A23C9/13
Inventor 康佳琪任宪锋张杰俞伟祖马莉孙亚婷郑利君姜利董阳刘叶婷王志涛王鹤楠李文清李源白皓雪
Owner INNER MONGOLIA MENGNIU DAIRY IND (GRP) CO LTD
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