Sustained-release microcapsule wrapping traditional Chinese medicine extract and preparation method and application thereof

A technology of extracts and traditional Chinese medicines, applied in the field of slow-release microcapsules wrapped with Chinese medicine extracts and its preparation, can solve the problems of not being able to repair the skin barrier, not being able to reach the deep layer of the skin, and not being able to achieve skin care effects, so as to slow down the skin Oxidation and melanin deposition, promotion of skin metabolism, and the effect of inhibiting the production of oxygen free radicals

Pending Publication Date: 2022-02-08
安徽德正堂药业集团有限公司
View PDF5 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to solve the problem of directly adding Chinese medicine extracts to skin care products for mixed emulsification in the prior art. Due to the special chemical structure of the active ingredients of Chinese medicine, it is very easy to lose biological activity

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The present invention proposes a slow-release microcapsule for wrapping traditional Chinese medicine extracts, the slow-release capsule includes a capsule core and a capsule material for wrapping the capsule core; the mass ratio of the capsule core is 20:1:1 The traditional Chinese medicine extract, ascorbyl palmitate and xylitol fatty acid ester are mixed and compounded; the capsule material is made of fatty acid sucrose polyester, ammonium lactate, hydroxypropyl di It is obtained by mixing starch phosphate and ethyl p-hydroxybenzoate;

[0023] The Chinese medicine extract is prepared by the following method: according to the solid-to-liquid ratio of 1:12, the mixed pulverized product of the dried Chinese medicine is stirred and dispersed with an ethanol solution with a concentration of 68%, and after the dispersion and mixing are uniform, at a temperature of 52°C, the ultrasonic power is Under the condition of 900W and microwave power of 300W, after ultrasonic microwa...

Embodiment 2

[0029] The present invention proposes a slow-release microcapsule for wrapping traditional Chinese medicine extracts, the slow-release capsule includes a capsule core and a capsule material for wrapping the capsule core; the mass ratio of the capsule core is 22:1.5:2 The traditional Chinese medicine extract, ascorbyl palmitate and xylitol fatty acid ester are mixed and compounded; the capsule material is made of fatty acid sucrose polyester, ammonium lactate, hydroxypropyl di It is obtained by mixing starch phosphate and ethyl p-hydroxybenzoate;

[0030] The Chinese medicine extract is prepared by the following method: according to the solid-to-liquid ratio of 1:15, the mixed pulverized product of the dried Chinese medicine is mixed with an ethanol solution with a concentration of 68% to stir and disperse, and after the dispersion and mixing are uniform, at a temperature of 62° C. Under the condition of 1050W and microwave power of 400W, after ultrasonic microwave extraction f...

Embodiment 3

[0036] The present invention proposes a slow-release microcapsule for wrapping traditional Chinese medicine extracts, the slow-release capsule includes a capsule core and a capsule material for wrapping the capsule core; the mass ratio of the capsule core is 24:2:3 The traditional Chinese medicine extract, ascorbyl palmitate and xylitol fatty acid ester are mixed and compounded; the capsule material is made of fatty acid sucrose polyester, ammonium lactate, hydroxypropyl di It is obtained by mixing starch phosphate and ethyl p-hydroxybenzoate;

[0037] The Chinese medicine extract is prepared by the following method: according to the solid-to-liquid ratio of 1:18, the mixed pulverized product of the dried Chinese medicine is mixed with an ethanol solution with a concentration of 68% to stir and disperse, and after the dispersion and mixing are uniform, at a temperature of 72° C. Under the condition of 1200W and microwave power of 500W, ultrasonic microwave extraction was carri...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Particle sizeaaaaaaaaaa
Particle sizeaaaaaaaaaa
Particle sizeaaaaaaaaaa
Login to view more

Abstract

The invention belongs to the technical field of skin care and health care products, particularly relates to a sustained-release microcapsule wrapping traditional Chinese medicine extract and a preparation method and application thereof, and solves the problems that in the prior art, the traditional Chinese medicine extract is directly added into a skin care product to be mixed and emulsified for use, due to the special chemical structure of traditional Chinese medicine active ingredients, the biological activity on the skin surface is extremely easy to lose, the active ingredients cannot reach the deep layer of the skin, cannot repair the skin barrier and cannot achieve a remarkable skin care effect. The sustained-release microcapsule wrapping the traditional Chinese medicine extract comprises a capsule core material and a capsule material wrapping the capsule core material; the capsule core material is prepared by mixing and compounding a traditional Chinese medicine extract, ascorbyl palmitate and xylitol fatty acid ester; the capsule material is prepared by mixing and compounding fatty acid sucrose polyester, ammonium lactate, hydroxy propyl distarch phosphate and ethyl p-hydroxybenzoate. The microcapsule can effectively ensure that the active ingredients of the traditional Chinese medicines can abut against the deep layer of the skin and are slowly released, thereby playing a role in repairing the skin barrier.

Description

technical field [0001] The invention relates to the technical field of skin care and health care products, in particular to a sustained-release microcapsule encapsulating a traditional Chinese medicine extract and a preparation method and application thereof. Background technique [0002] The narrow sense of the skin barrier mainly refers to the physical barrier, which is composed of sebum membrane, stratum corneum keratin, lipid, "sandwich" structure, brick wall structure, dermal mucopolysaccharides, mucopolysaccharides, etc. A healthy skin barrier protects against external harmful substances, irritants and sunlight while moisturizing and regulating. However, due to factors such as environment, diet and wrong skin care, the skin barrier is damaged, which makes the skin's own defense ability insufficient, and the skin is extremely sensitive and damaged. After the skin barrier is damaged, the moisturizing function will become poor, and phenomena such as external oil and inte...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K8/9789A61K8/11A61K8/67A61K8/37A61K8/85A61K8/73A61K8/365A61Q19/00A61Q19/08A61Q19/02A23L33/105A23L33/12A23L5/30A23P10/30
CPCA61K8/9789A61K8/11A61K8/676A61K8/375A61K8/85A61K8/732A61K8/37A61K8/365A61Q19/00A61Q19/08A61Q19/02A61Q19/005A23L33/105A23L33/12A23L5/32A23P10/30A23V2002/00A23V2200/318A23V2200/302A23V2250/21A23V2300/14A23V2300/48
Inventor 金德利
Owner 安徽德正堂药业集团有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap