The invention relates to a clothing acarus killing care detergent, and belongs to the technical field of cleaning agents. Sodium dodecyl benzene sulfonate and calcium chloride serve as raw materials,sodium carbonate is added, acarus killing active matters with micro-capsule structures are formed, and anti-acarus slow release is performed, so that a fabric achieves long-acting anti-acarus effects.Sucrose polyester serves as a raw material, iso-tridecanol polyoxyethylene ether, Tween-80 and the like are added to serve as emulsifiers, fiber surface energy is reduced, fiber friction coefficientis decreased, the fibrillation degree of fibers is weakened, and the elasticity and surface smoothness of the fabric are improved. Decamethyl pentasiloxane, 1, 3-bis (3-amino propyl)-1, 1, 3, 3-tetramethyl disiloxane serve as raw materials, an intermediate is synthesized, hexanedioic acid, Hexanediamine and the like serve as raw materials, a block matrix is synthesized, and care durability is improved. The fabric is cleaned, foamed and wetted by adding tea saponin, and the color and luster of the fabric is improved. The clothing acarus killing care detergent solves the problems that a currentclothing detergent is poor in anti-acarus effect, and washed fabrics are poor in softness and color and luster.