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Pachymaran extract and application thereof in ultraviolet resistance

A polysaccharide and anti-ultraviolet technology, which is applied in the direction of medical preparations containing active ingredients, drug combinations, preparations for toiletry, etc., can solve the problem that the anti-ultraviolet properties of polysaccharide extracts have not been studied

Active Publication Date: 2022-03-08
SHANGHAI INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, the anti-oxidation and moisturizing properties of the pachyrhiza extract have been studied, but the anti-ultraviolet property of the pachyma polysaccharide extract has not been studied

Method used

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  • Pachymaran extract and application thereof in ultraviolet resistance
  • Pachymaran extract and application thereof in ultraviolet resistance
  • Pachymaran extract and application thereof in ultraviolet resistance

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0075] Dry the poria cocos block at room temperature at 48±2°C for 48 hours, grind the powder with a machine, and pass through an 80-mesh sieve to obtain powdered poria cocos.

[0076] Take poria cocos powder and water, mix and dissolve uniformly according to a certain ratio of material to liquid, and extract in an ultrasonic extraction device by means of a water bath; after ultrasonication, centrifuge at a speed of 4000r / min for 20 minutes, filter the upper liquid, and obtain the filtrate As the extract material liquid of Poria cocos polysaccharide.

[0077] Determination of Poria cocos polysaccharide content in the extract material liquid of Poria cocos polysaccharide:

[0078] Pipette 1mL of the sample to be tested (Poria cocos polysaccharide extract material liquid) in a 20mL test tube, add 0.5mL of 5wt% phenol solution to the test tube, mix well, then quickly add 2.5mL of concentrated sulfuric acid; then put the test tube into boiling water for heating 15min, then take i...

Embodiment 2

[0105] Extraction method of Poria cocos polysaccharide extract

[0106] Dry the poria cocos block at room temperature at 48±2°C for 48 hours, grind the powder with a machine, and pass through an 80-mesh sieve to obtain powdered poria cocos. Take poria cocos powder and water according to the ratio of 1:20 (g:mL), uniformly mix and dissolve, and extract in an ultrasonic extraction device in a water bath; the ultrasonic temperature is 33°C, the ultrasonic power is 208W, and the ultrasonic time is 16 min; centrifuge at a speed of 4000 r / min for 20 minutes after sonication, filter the liquid in the upper layer, and concentrate the obtained filtrate to 10% of the volume of the original filtrate to obtain a pachyrhin extract.

[0107] Utilize the method of embodiment 1 to measure the yield of pachyphyllan in the polysaccharide polysaccharide obtained is 2.001%.

[0108] Poria polysaccharide meter, adopt water to dissolve the polysaccharide polysaccharide extract, obtain the polysacc...

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Abstract

The invention belongs to the technical field of substance extraction, and provides a pachymaran extract and an application thereof in ultraviolet resistance. The pachymaran extract provided by the invention has excellent ultraviolet resistance, so that the pachymaran extract can be used in the field of ultraviolet resistance, such as sun-screening agent products. Meanwhile, the pachymaran extract provided by the invention also has moisture retention, oxidation resistance and tyrosinase inhibition effect, that is, the pachymaran extract has the effects of moisturizing and whitening, and is expected to be applied to whitening and moisturizing cosmetics. Furthermore, the extraction method of the pachymaran extract is simple, and the extraction period is short; and the yield of the obtained pachymaran extract is high.

Description

technical field [0001] The invention relates to the technical field of substance extraction, in particular to an extract of Poria cocos polysaccharide and its application in anti-ultraviolet rays. Background technique [0002] Poria cocos polysaccharides mainly exist in the cell wall of Poria cocos, and there are polysaccharides soluble in aqueous solution and polysaccharides soluble in alkaline solution. Modern clinical and pharmacological studies have shown that Poria polysaccharide has a good anti-tumor effect. The sugar can enhance the cytotoxicity of macrophages and T lymphocytes, and can also enhance the immune response of cells and activate the body's immune surveillance system against tumors. The mechanism is related to the activation of complement. [0003] The method for extracting the polysaccharide extract from Poria cocos includes a water extraction method, an enzyme-assisted method and a microwave-assisted extraction method. The types of substances contained ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/73A61K31/715A61P17/16A61Q19/00A61Q19/08C08B37/00
CPCA61K8/73A61K31/715A61P17/16C08B37/0003A61Q19/08A61Q19/00A61K2800/82Y02A50/30
Inventor 李姗姗王伟文琳刘清雷
Owner SHANGHAI INST OF TECH
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