Azoxystrobin eutectic mixture as well as preparation method and application thereof
A deep eutectic mixture, azoxystrobin technology, applied in the field of pesticide chemistry, can solve the problems of unfavorable concentrated solution preparation and low solubility
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
preparation example Construction
[0127] Another preparation method may include the steps of: providing a mixture of azoxystrobin and the ligand in solid form; grinding the mixture to obtain the azoxystrobin eutectic mixture.
[0128] Pesticide composition, use
[0129] The "active ingredient" or "active compound" in the pesticide composition of the present invention refers to the compound of formula I described in the present invention, especially the compound of formula I present in the eutectic mixture of the present invention.
[0130] In another preferred example, based on the total weight of the active ingredients, the weight percentage of the eutectic mixture VI, VII, VIII, IX, or a combination thereof is 60-99.999%, preferably 80% -99.999%, more preferably 90-99.999%.
[0131] In another preferred example, the pesticide composition further includes at least one agricultural adjuvant, such as water.
[0132] The "active ingredient" or "active compound" and the pesticide composition of the present inve...
Embodiment 1
[0158] Embodiment 1. Preparation of azoxystrobin eutectic mixture VI
[0159] Weigh 80.6mg (0.2mmol) of azoxystrobin (AZO) and 49.6mg (0.2mmol) of fludioxonil (FDO) in a container, add an appropriate amount of acetone to dissolve, then quickly spin evaporate, and obtain azoxystrobin after vacuum drying of the solid Eutectic VI (97% yield).
[0160] Weigh 4.03g (10mmol) azoxystrobin (AZO) and 2.48g (10mmol) fludioxonil (FDO) into the reaction flask, add appropriate amount of N,N dimethylacetamide solvent (10g) at 20°C, 300rpm / Stir under the condition of min to dissolve, then add 100g of water, add slowly, continue to stir for 1h after the addition, filter, and dry the solid in vacuum to obtain the azoxystrobin eutectic mixture VI (yield 97%).
[0161] The azoxystrobin eutectic mixture VI of gained, its XRPD collection of patterns is substantially as figure 1 As shown, the diffraction angle data are basically shown in Table 1 below.
[0162] Table 1 XRPD data of eutectic mix...
Embodiment 2
[0169] Example 2. Stability investigation of azoxystrobin eutectic mixture VI
[0170] The sample of the azoxystrobin eutectic mixture VI (the molar ratio of azoxystrobin and fludioxonil is 7:3) in Example 1 was placed at high temperature (60±2°C), high humidity (RH92.5%), light (4500lx±500lx), the samples were taken out after 5 days and 10 days for XRPD test to investigate the stability of the samples to temperature, humidity and light. Such as Figure 4 , Figure 5 , Figure 6 , Figure 7 , Figure 8 and Figure 9 As shown, the results show that the eutectic mixture VI samples are stable under high temperature, high humidity and light conditions.
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More