Fluorescent probe for environment detection as well as preparation method and application of fluorescent probe

Abstract

The invention discloses a fluorescent probe for environment detection and a preparation method and application thereof.The fluorescent probe has the structural formula shown in the formula (1), is prepared from a compound A and a compound B through synthesis, is stable in optical performance (the probe can be stably stored at the room temperature for six months or above, and the spectral property of the probe is kept unchanged), high in sensitivity and high in copper ion recognition capacity, and can be used for detecting copper ions. During detection, the solution is changed from yellow to red, naked eye recognition can be realized, the selectivity is good, the response speed is relatively high (the response time is 5 minutes), the response range is 0.1-10 [mu] mol.L <-1 >, the detection limit is low (34nM, a method based on 3 times of blank sample standard deviation given by the International Pure and Application Chemical Combination), and the method can be used for detecting copper ions in a water body and a biological system; the preparation method is simple, raw materials are easy to obtain, and the synthesis yield is high.

Description

technical field [0001] The invention relates to the technical field of chemical analysis and detection, in particular to a fluorescent probe used for environmental detection and a preparation method and application thereof. Background technique [0002] Copper is the third most essential trace element in the human body and plays a very important role in many physiological processes, such as maintaining the functional structure of proteins, participating in cellular respiration, gene expression and related metalloenzyme catalysis reactions. On the other hand, abnormal copper content and metabolic disorders can lead to oxidative stress responses associated with a series of neurodegenerative diseases (such as Alzheimer's disease, Parkinson's disease, prion disease, etc.). The U.S. Environmental Protection Agency stipulates that the safe limit value of copper ions is 1.3ppm (20μmol·L -1 ). In view of the important physiological and pathological functions of copper ions, it is ...

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Problems solved by technology

[0004] The invention provides a fluorescent probe for environmental engineering monitoring and detection and its preparation method and application to solve the problem that the current existing detection methods take a long time, involve complicated and cumbersome sample processing processes, or require expensive precision instruments disadvantages, as well as the technical problem that existing fluorescent probes are difficult to deal with complex sample background interference

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