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Medical wet dressing and preparation method thereof

A wet dressing and spinning solution technology, applied in fiber processing, textiles and papermaking, conjugated synthetic polymer artificial filaments, etc., can solve the problems of wound dehydration, excessive dosage, and inability to promote wound healing

Pending Publication Date: 2022-07-01
山东万容生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional medical dressings mainly include gauze, bandages, etc. The production and processing process of these traditional dressings is relatively simple, and they have the effect of quickly absorbing wound exudate, but they are often too high in permeability, which easily dehydrates the wound, and the chance of cross-infection is relatively low. High; and the dosage is usually large, it needs to be replaced frequently, and at the same time it will stick to the wound surface, which will cause mechanical damage again and increase the pain of the patient. promote wound healing

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0023] The embodiment of the present invention provides a preparation method of a medical wet dressing, which includes the following steps: taking chitosan and polyethylene oxide, adding them to an acetic acid solution, stirring and dissolving, and then standing to obtain a spinning solution; Add it into a syringe, perform electrospinning to obtain a spinning film; take medical zinc oxide, add water to prepare a suspension, put the spinning film into the suspension, soak and ultrasonically treat it, and then dry it to obtain finished product.

[0024] In the above embodiment, the spinning film is prepared by electrospinning with chitosan and polyethylene oxide as the main raw materials. Among them, chitosan is the product of natural polysaccharide chitin removing part of the acetyl group. It has various physiological functions such as biodegradability, biocompatibility, non-toxicity, antibacterial, anti-cancer, lipid-lowering, hemostasis, and immunity enhancement. It also has...

Embodiment 1

[0045] The present embodiment provides a medical wet dressing, which is prepared by the following method:

[0046] Take chitosan and polyethylene oxide at a weight ratio of 7:1, add them to 80% acetic acid solution, stir to dissolve and then stand to obtain 3wt% spinning solution; add the spinning solution to a syringe, and at 30kV, 15cm The working distance of 0.5ml / h was carried out by electrospinning at a spinning solution advancing rate of 0.5ml / h to obtain a spinning film, and then the spinning film was cross-linked by glutaraldehyde vapor for 12h, and then dried in a vacuum drying box at 40 Dry at ℃; take 0.03g of medical zinc oxide, add 40g of water to prepare a suspension, put the spinning film into the suspension, soak and ultrasonically treat it for 60min, and then freeze-dry it at -20℃ to obtain the finished product .

Embodiment 2

[0048] The present embodiment provides a medical wet dressing, which is prepared by the following method:

[0049] Take chitosan and polyethylene oxide in a weight ratio of 8:1, add them to a 90% acetic acid solution, stir to dissolve and then stand to obtain 5wt% spinning solution; add the spinning solution to a syringe, at 20kV, 20cm The working distance was 1.0 ml / h, and electrospinning was carried out at a spinning solution advancing rate of 1.0 ml / h to obtain a spinning film, and then the spinning film was cross-linked by glutaraldehyde vapor for 10 h, and then dried in a vacuum drying box at 35 Dry at ℃; take 0.03g of medical zinc oxide, add 25g of water to prepare a suspension, put the spinning film into the suspension, soak and ultrasonically treat it for 60min, and then freeze-dry it at -20℃ to obtain the finished product .

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PUM

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Abstract

The invention provides a medical wet dressing and a preparation method thereof, and relates to the technical field of medical dressings. The invention relates to a preparation method of a medical wet dressing, which comprises the following steps: adding chitosan and polyoxyethylene into an acetic acid solution, stirring and dissolving, and standing to obtain a spinning solution; adding the spinning solution into an injector, and carrying out electrostatic spinning to obtain a spinning membrane; taking medical zinc oxide, adding water to prepare turbid liquid, putting the spinning membrane into the turbid liquid, soaking and performing ultrasonic treatment, and then drying to obtain a finished product; the method is simple in process, and the prepared product dressing is good in use effect. The wet dressing is prepared by the preparation method, and can effectively protect the wound surface, provide a healing environment for the wound, promote wound healing and prevent cross infection.

Description

technical field [0001] The invention relates to the technical field of medical dressings, in particular to a medical wet dressing and a preparation method thereof. Background technique [0002] The skin is an organ that is wrapped on the surface of the body and is in direct contact with the external environment. It has the functions of protecting, excreting, regulating body temperature and sensing external stimuli. It is also the largest organ in the human body and is also the most vulnerable to external damage. organ. The skin has a strong ability to repair and regenerate. When the skin is injured and the skin tissue is severed or damaged, the skin will heal itself. During the healing process, the wound is vulnerable to external infection, so it is necessary to use medical dressings to treat the wound. Protect. Traditional medical dressings mainly include gauze, bandages, etc. The production and processing process of these traditional dressings is relatively simple and ha...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): D04H1/728D04H1/4291D01F8/16D01F8/18D06M11/44D06M13/123D06M101/30
CPCD04H1/728D04H1/4291D01F8/16D01F8/18D06M11/44D06M13/123D06M16/00D10B2401/13D10B2401/12D10B2509/022D06M2101/30D06M2200/25
Inventor 徐会军
Owner 山东万容生物科技有限公司
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