Medical wet dressing and preparation method thereof
A wet dressing and spinning solution technology, applied in fiber processing, textiles and papermaking, conjugated synthetic polymer artificial filaments, etc., can solve the problems of wound dehydration, excessive dosage, and inability to promote wound healing
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[0023] The embodiment of the present invention provides a preparation method of a medical wet dressing, which includes the following steps: taking chitosan and polyethylene oxide, adding them to an acetic acid solution, stirring and dissolving, and then standing to obtain a spinning solution; Add it into a syringe, perform electrospinning to obtain a spinning film; take medical zinc oxide, add water to prepare a suspension, put the spinning film into the suspension, soak and ultrasonically treat it, and then dry it to obtain finished product.
[0024] In the above embodiment, the spinning film is prepared by electrospinning with chitosan and polyethylene oxide as the main raw materials. Among them, chitosan is the product of natural polysaccharide chitin removing part of the acetyl group. It has various physiological functions such as biodegradability, biocompatibility, non-toxicity, antibacterial, anti-cancer, lipid-lowering, hemostasis, and immunity enhancement. It also has...
Embodiment 1
[0045] The present embodiment provides a medical wet dressing, which is prepared by the following method:
[0046] Take chitosan and polyethylene oxide at a weight ratio of 7:1, add them to 80% acetic acid solution, stir to dissolve and then stand to obtain 3wt% spinning solution; add the spinning solution to a syringe, and at 30kV, 15cm The working distance of 0.5ml / h was carried out by electrospinning at a spinning solution advancing rate of 0.5ml / h to obtain a spinning film, and then the spinning film was cross-linked by glutaraldehyde vapor for 12h, and then dried in a vacuum drying box at 40 Dry at ℃; take 0.03g of medical zinc oxide, add 40g of water to prepare a suspension, put the spinning film into the suspension, soak and ultrasonically treat it for 60min, and then freeze-dry it at -20℃ to obtain the finished product .
Embodiment 2
[0048] The present embodiment provides a medical wet dressing, which is prepared by the following method:
[0049] Take chitosan and polyethylene oxide in a weight ratio of 8:1, add them to a 90% acetic acid solution, stir to dissolve and then stand to obtain 5wt% spinning solution; add the spinning solution to a syringe, at 20kV, 20cm The working distance was 1.0 ml / h, and electrospinning was carried out at a spinning solution advancing rate of 1.0 ml / h to obtain a spinning film, and then the spinning film was cross-linked by glutaraldehyde vapor for 10 h, and then dried in a vacuum drying box at 35 Dry at ℃; take 0.03g of medical zinc oxide, add 25g of water to prepare a suspension, put the spinning film into the suspension, soak and ultrasonically treat it for 60min, and then freeze-dry it at -20℃ to obtain the finished product .
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