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Lactobacillus and application thereof

A lactobacillus, decomposition technology, applied in the direction of application, bacteria, medical preparations containing active ingredients, etc., can solve the problems of food taste components reduction, malnutrition, etc.

Pending Publication Date: 2022-08-02
丁庆 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, dietary restriction of purines is used as a preventive measure for hyperuricemia, but restriction of purines can cause problems such as malnutrition and reduced taste components of food

Method used

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  • Lactobacillus and application thereof
  • Lactobacillus and application thereof

Examples

Experimental program
Comparison scheme
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Embodiment 1

[0026] Animal experiment:

[0027] Three Lactobacillus strains were selected and cultured anaerobic. Include Bifidobacterium, Lactobacillus, Enterococcus to prepare washed cells. It was suspended in 0.1 M phosphate buffer (pH 7.0) containing 1.25 mM inosine and guanosine each, shaken at 37 °C for 2 h under anaerobic conditions, and then inosine and guanosine were shaken in the reaction supernatant. Guanosine. Metabolism was assessed by analyzing concentrations.

[0028] Fifteen 8-week-old Wister male rats were fed a diet supplemented with a uricase inhibitor (2.5% phosphate) and a purine source (1.0% RNA) for 1 week to prepare dietary hyperuricemia model rats .

[0029] Lactobacillus strains from 3 food sources previously searched in this model rat were orally administered with 1.0 × 109 CFU, and the tail vein was collected before ingestion and 2, 5, and 8 days after ingestion to determine blood uric acid levels. Tungsten method. The control group (oxoate + RNA) and the ...

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PUM

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Abstract

The invention relates to lactobacillus, which is preserved in China General Microbiological Culture Collection Center (CGMCC) on August 28, 2018, has the preservation number of CGMCC No.16350, and is lactobacillus with a purine decomposition effect.

Description

technical field [0001] The invention belongs to the technical field of bacterial strain application, relates to a lactobacillus and an application thereof, in particular to a lactobacillus having purine decomposition effect and no gas-producing ability and an application thereof. Background technique [0002] Purine is a component of DNA and other substances in cells, and is actually an indispensable energy source for living organisms to carry out life activities. In addition, almost all foods contain purines, which are not only obtained from the diet, but originally present in the body. Purines are broken down into uric acid in the body, stored in uric acid pools, and finally excreted with urine. In order to maintain health in daily life, it is important to balance the intake / production and excretion of uric acid. [0003] The daily intake of purine bodies should be within 400mg, but with the continuous enrichment of dietary life and the improvement of nutritional quality...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12N1/20A23L33/135A23L2/52A23K10/18A23L3/3571A61K35/747A61P19/06C12R1/245
CPCC12N1/20A23L33/135A23L2/52A23K10/18A23L3/3571A61K35/747A61P19/06A23V2002/00A23V2400/165A23V2200/30Y02A50/30
Inventor 丁庆曾筱芳
Owner 丁庆
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