413 results about "Doderlein's bacillus" patented technology

The invention relates to the field of biotechnology and female health care, in particular to a stachyose composition for promoting micro-ecological regulation of lactobacillus and application of the stachyose composition, and the composition comprises stachyose and pharmaceutically acceptable auxiliary materials. The stachyose is used as prebiotics to selectively promote proliferation and colonization of the lactobacillus crispatus, the combination of 1%-5% of the stachyose and 0.1%-0.5% of the lactic acid can promote proliferation of the lactobacillus crispatus, the lactobacillus crispatus is one or more of the lactobacillus crispatus, the lactobacillus plantarum and the lactobacillus acidophilus, and the combination of 1%-5% of the stachyose and 0.1%-0.5% of the lactic acid can inhibit gardnerella and candida albicans. The stachyose composition disclosed by the invention is in the form of slow-release gel and bath foam; the composition can be used for treating or preventing bacterial vaginitis, colpitis mycotica and related symptoms, has the advantages of no antibiotics, no drug resistance, high safety and the like, and is suitable for the fields of vagina local nursing and micro-ecological regulation.

The invention discloses lactobacillus mucus HG002 and application thereof, and belongs to the field of microbial medicine. The lactobacillus mucilaginosus HG002 is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation number is CGMCC NO.36670, and the 16S rDNA gene sequence of the lactobacillus mucilaginosus HG002 is as shown in SEQ ID NO: 1. The strain is separated from excrement of healthy adults, the relieving effect of ALF is remarkably improved through the brand-new fermentation lactobacillus mucus HG002 strain and derivative EVs thereof in combination with a synergistic effect mechanism and optimized product design, many defects in the prior art are overcome, and wide application prospects and industrialization value are achieved.

The invention discloses a lactobacillus reuteri strain and an application of the lactobacillus reuteri strain in poultry breeding. The strain name of the lactobacillus reuteri strain is Lac-R30, and the lactobacillus reuteri strain is preserved in the Guangdong Microbial Culture Collection Center, and the preservation number is GDMCC NO. 66690. According to the invention, the lactobacillus with high adhesiveness is separated and screened from the intestinal tract of chicken, which is crucial for ensuring the effective colonization and probiotic function exertion of the lactobacillus in the intestinal tract of poultry. The adhesiveness and field planting efficiency of the lactobacillus reuteri strain Lac-R30 in intestinal tracts are not reported, and the breakthrough of strain resources is realized. The lactobacillus reuteri strain Lac-R30 disclosed by the invention has remarkable advantages in adhesiveness and field planting efficiency due to high adaptability of the lactobacillus reuteri strain Lac-R30 to poultry hosts. The lactobacillus reuteri strain Lac-R30 disclosed by the invention not only provides a high-quality strain resource for researching and developing a poultry probiotic preparation which is more efficient and more targeted, but also lays a solid foundation for improving the application effect of probiotics in actual breeding.

The invention relates to the technical field of microorganisms, and discloses a lactobacillus delbrueckii subsp. Bulgaricus XJFY201503 and an application thereof in improving an immune function, the lactobacillus delbrueckii subsp. Bulgaricus XJFY201503 is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation number is CGMCC NO.30047, and the preservation time is March 18, 2024. The lactobacillus delbrueckii subsp. Bulgaricus XJFY201503 can be used for directly improving the immune function of an immunosuppressive mouse by protecting and maintaining normal physiological structures of central and peripheral immune organs and promoting secretion of serum cytokines and immune globulins; and the immune function of the mouse can be indirectly promoted by relieving intestinal inflammation reaction.

The invention provides a preparation method and application of a bacterium-enzyme-magnetic nano-cluster composite detoxicating agent, the detoxicating agent takes a Fe3O4-HAP nano-cluster as a magnetic core, the surface of the detoxicating agent is subjected to functional modification, a composite flora composed of bacillus amyloliquefaciens, lactobacillus plantarum and saccharomyces cerevisiae is loaded to form sclerotia, a chitosan shell layer is constructed on the outermost layer, and the bacterium-enzyme-magnetic nano-cluster composite detoxicating agent is prepared. And a compound enzyme consisting of aflatoxin Bdegrading enzyme, zearalenone hydrolase and deoxynivalenol invertase is immobilized. The carrier can efficiently and synchronously degrade aflatoxin, vomitoxin and zearalenone, and can realize rapid separation and recovery through an external magnetic field.

The invention relates to the technical field of microorganisms, in particular to a complex microbial inoculant for resisting salmonella infection and application of the complex microbial inoculant. The invention provides a microbial composition for resisting salmonella infection. The microbial composition comprises lactobacillus reuteri, lactobacillus mucosa, lactobacillus plantarum, lactobacillus bulgaricus and pediococcus pentosaceus. Results of the embodiment of the invention show that the complex microbial inoculant provided by the invention has an excellent anti-salmonella typhimurium effect, and only the anti-salmonella typhimurium effect of the complex microbial inoculant in a specific proportion provided by the invention is optimal; meanwhile, the complex microbial inoculant can effectively relieve the harm of salmonella typhimurium to chickens, improve the growth performance of the chickens and improve the immunity of the chickens. The invention provides a new prevention and treatment thought for salmonella.

The invention discloses PDRN and a preparation method and application thereof.The base sequence of the PDRN is shown as SEQ ID NO1, and the preparation method of the PDRN comprises the following steps that fermentation treatment is conducted through lactobacillus plantarum, and thalli are collected after an obtained fermentation culture solution is centrifuged; and resuspending the obtained thalli, homogenizing and crushing, centrifuging to remove precipitate, concentrating by using a 5kDa hollow fiber membrane, purifying the obtained concentrated solution by using a Q column, and then concentrating and changing the solution to obtain the high-purity PDRN. According to the method, the PDRN is obtained through fermentation of lactobacillus plantarum for the first time, compared with PDRN sourced from salmon or salmon and the like at present, the method is lower in production cost, and a new way is provided for PDRN production. The PDRN obtained by the method disclosed by the invention is high in purity and single in molecular weight, and experiments prove that the PDRN obtained by the method disclosed by the invention has higher activity in the aspects of promoting cell proliferation, promoting collagen generation and the like.

Provided are a mixture of three species of Lactobacillus fermentum strain and Lactobacillus plantarum strain and use thereof. A composition according to one aspect including, as an active ingredient, a mixture of Lactobacillus fermentum strains GB102 and GB103 and Lactobacillus plantarum strain GB104; or a lysate or culture solution thereof, or an extract of the culture solution, can be usefully used for the prevention or treatment of muscle-related disorders or obesity by alleviating the decrease in grip strength induced by aging or reducing the change in intestinal microbial environment induced by aging.

The invention relates to a strain of Lactobacillus coryniformis ZS-07 and an application of the Lactobacillus coryniformis ZS-07 in preparation of rare ginsenoside through fermentation, and belongs to the field of microbial fermentation, the Lactobacillus coryniformis ZS-07 is preserved in China Center for Type Culture Collection on January 4, 2026, and the preservation number of the Lactobacillus coryniformis ZS-07 is CCTCC NO: M 2026009. According to the invention, ginsenoside Rb1 is used as a raw material, and the rare ginsenosides 20 (S)-Rg3, 20 (R)-Rg3, Rk1 and Rg5 are prepared by fermentation and conversion of Lactobacillus coryniformis ZS-07. The preparation method comprises the following steps: preparing the rare ginsenosides 20 (S)-Rg3, 20 (R)-Rg3, 20 (R)-Rg3, Rk1 and Rg5; the ginsenoside Rb1 can be converted into 20 (S)-Rg3, 20 (R)-Rg3, Rk1 and Rg5 after fermentation, and different from conventional methods depending on alkaline hydrolysis, high temperature and high pressure or steam treatment, the process shows the advantages of excellent mild characteristic, environmental friendliness and low cost, and the content of converted products can be effectively increased. The invention constructs a new strategy for directional synthesis of rare ginsenosides 20 (S)-Rg3, 20 (R)-Rg3, Rk1 and Rg5, thereby widening the application prospect and industrialization potential of the rare ginsenosides 20 (S)-Rg3, 20 (R)-Rg3, Rk1 and Rg5.

The invention discloses lactobacillus mucus YF28 and application thereof, and belongs to the technical field of microorganisms. The fermented lactobacillus mucus YF28 is separated from Hu sheep manure, is classified and named as the fermented lactobacillus mucus YF28, and has the preservation number of CCTCC (China Center For Type Culture Collection) NO: M 20252433. The fermented lactobacillus mucilaginosus YF28 has good tolerance in the gastrointestinal environment and can reach the intestinal tract to play a role. The bacterial strain has strong intestinal adhesion capacity, is easy to form a probiotic biological membrane, and is beneficial to intestinal health. The fermented lactobacillus mucus YF28 can promote peristalsis, enrich the abundance of Akkermansia bacteria and bacteriophage thereof, restore the water content of excrement to a normal level, and significantly promote intestinal health. The invention has an application prospect in the development of drugs or health-care foods with the function of relieving constipation and related gastrointestinal symptoms.

The invention discloses lactobacillus plantarum, the Latin name of the lactobacillus plantarum is Lactiplantarum, the lactobacillus plantarum is named as BQ-3, the lactobacillus plantarum is preserved in Guangdong Microbial Culture Collection Center on January 15, 2025, and the preservation registration number of the lactobacillus plantarum is GDMCC No.65791; secondly, the invention further discloses a microbial fermentation agent, and the effective components of the microbial fermentation agent comprise the lactobacillus plantarum. In addition, the invention also discloses an application of the lactobacillus plantarum or the microbial fermentation agent in fermentation of the rotten vegetable leaves, and an application of the fermented rotten vegetable leaves prepared by the application of the lactobacillus plantarum or the microbial fermentation agent in fermentation of the rotten vegetable leaves in fattening feed. The lactobacillus plantarum strain disclosed by the invention has the beneficial effects that the lactobacillus plantarum strain is separated and screened from naturally-fermented rotten vegetable leaves, and has the characteristics of high lactic acid production speed and high yield; when applied to the fermentation of the rotten vegetable leaves, the strain can quickly produce acid, reduce the pH value, reduce the loss of dry matters, retain nutrients, inhibit the generation of ammoniacal nitrogen and putrefying acid, significantly improve the fermentation quality and prolong the storage life; the feed additive can promote fattening growth of livestock when applied to feeds.

The invention discloses a culture device for improving polycystic ovarian syndrome lactobacillus reuteri, and belongs to the technical field of lactobacillus reuteri culture.The culture device comprises a working frame, the inner side of the working frame is fixedly connected with a feeding mechanism used for conveying, one side of the feeding mechanism is fixedly connected with a culture mechanism, and the other side of the feeding mechanism is fixedly connected with a conveying mechanism; a liquid feeding mechanism is fixedly connected to the rear side of the feeding mechanism, a supporting mechanism is fixedly connected to the position, located between the feeding mechanism and the culture mechanism, of the inner side of the working frame, an auxiliary ladder is fixedly connected to the surface of one side of the working frame, and a protection frame is fixedly connected to the surface of the auxiliary ladder. On the basis of realizing auxiliary culture of lactobacillus reuteri, strain functions and metabolites can be accurately regulated and controlled, and the delivery problem in PCOS treatment can be solved.

The invention belongs to the technical field of microbiological detection, and discloses a PCR primer combination for detecting mixed microorganisms in a food fermentation process and a detection method thereof. The primer combination comprises a primer pair used for detecting pediococcus pentosaceus, a primer pair used for detecting plant lactobacillus, a primer pair used for detecting lactobacillus mucus fermentation, a primer pair used for detecting bacillus amyloliquefaciens and a primer pair used for detecting lactobacillus acidophilus. The primer pair is at least one of a primer pair for detecting lactobacillus helveticus and a primer pair for detecting acetobacter pasteurianus. The primer combination or the kit containing the primer combination can realize species level specific detection of microorganisms, and can be used for qualitatively / quantitatively detecting food and key functional microorganisms in the food fermentation process, so that the dynamic change of a target flora in the fermentation process is quickly and accurately monitored.

This invention provides a *Lactobacillus plantarum* LN-Lp1 strain, its applications, products, and methods, belonging to the field of probiotic technology. The *Lactobacillus plantarum* LN-Lp1 strain has the accession number CGMCC 33158. This LN-Lp1 strain was deposited on December 23, 2024, at the China General Microbiological Culture Collection Center, located at No. 3, Courtyard 1, Beichen West Road, Chaoyang District, Beijing. Based on this strain, this invention also provides its uses and related products. This LN-Lp1 strain exhibits strong resistance to simulated gastric-intestinal stress and good intestinal adhesion and colonization potential. The *Lactobacillus plantarum* LN-Lp1 of this invention has excellent weight-loss effects, improving lipid metabolism and lowering blood lipid levels.

The invention discloses an intestinal flora delivery system based on a lactobacillus biological membrane and a preparation method of the intestinal flora delivery system, the intestinal flora delivery system is based on the lactobacillus biological membrane, and the biological membrane particularly refers to a biological membrane system which is induced by lactobacillus spp. Through optimized culture conditions and is mature in structure. And after physical collection and mild homogenization treatment, a biological membrane fragment suspension mainly composed of an extracellular polymeric matrix is obtained. According to the invention, a treated lactobacillus biofilm matrix is used as a core carrier, and a compact natural three-dimensional network structure can provide an excellent physical barrier; meanwhile, the biological matrix has chemical buffering potential and good biocompatibility.

The invention belongs to the technical field of microorganisms, and particularly relates to combined lactobacillus salivarius and application thereof in female genital tract health. The preservation number of the strain is CCTCC NO: M20231719, and the strain has good bacteriostatic ability and dendritic cell (DC) maturation / activation stimulation ability, has no potential safety problem, can regulate vaginal micro-ecological balance, prevent infection caused by exogenous bacteria, effectively improve tumor immunosuppression microenvironment, and has good application prospects. And the method has very important significance on prevention / treatment of vaginal dysbacteriosis patients, gynecological tumors and precancerous lesions thereof.

The invention provides a leavening agent and a preparation method thereof, and belongs to the technical field of leavening agents. According to the scheme, an efficient fermentation system is constructed through the synergistic effect of bacillus amyloliquefaciens, bacillus licheniformis, lactobacillus plantarum and saccharomyces cerevisiae, in the initial stage, the bacillus amyloliquefaciens secretes amylase and phytase degradation substrates, and conditions are created for the saccharomyces cerevisiae to metabolize monosaccharide to generate flavor substances and vitamins; in the middle stage, bacillus licheniformis decomposes protein to release amino acid, lactobacillus plantarum regulates pH through lactic acid metabolism to inhibit infectious microbes, and a multi-layer encapsulated compound enzyme preparation is introduced to synergistically degrade a complex substrate; in the later stage, fructooligosaccharide in the prebiotics-buffer stabilizer promotes proliferation of probiotics, mannitol and chitosan protect the activity of thalli and the function of metabolic enzymes, and the fermentation environment is stabilized; according to the whole system, the functionality, the environmental adaptability and the storage stability of the leavening agent are improved through flora synergistic metabolism, dynamic fermentation condition control and the action of the multifunctional additive, and the diversified requirements in industrial production are met.

The invention belongs to the technical field of biology, and particularly relates to a complex microbial inoculant for promoting formation of a biological membrane, a microcapsule and application of the complex microbial inoculant. The complex microbial inoculant comprises lactobacillus mucus fermentation FMBL L24016DMX with the preservation number of CCTCC NO: M20241583 and bifidobacterium longum subsp. Longum FMBL B241770LS with the preservation number of CCTCC NO: M 20241993, the complex microbial inoculant can grow on a culture medium containing prebiotics, the biofilm formation amount is the highest when the complex microbial inoculant is co-cultured in a culture medium containing isomaltooligosacharide, the complex microbial inoculant is prepared into a single-layer microcapsule or a double-layer microcapsule, and the complex microbial inoculant can be used for preparing the probiotics. The endophytic fungus has good embedding rate and viable count, can resist gastrointestinal environment, has good heat resistance, and has wide application prospects.

The invention belongs to the technical field of bioengineering and microbiomics, and particularly relates to an acquisition method and application of a specific metabolic substrate of lactobacillus crispatus and application of a specific carbohydrate active enzyme CAZzyme gene and a polysaccharide utilization site (PUL). Genomes of lactobacillus crispatus and lactobacillus inertus are obtained from a public database, gene annotation is carried out on the genomes of the lactobacillus crispatus and the lactobacillus inertus, and a random forest model and a KEGG metabolic pathway diagram are combined to find specific CAZzyme genes, PUL and other genes with metabolic functions of the lactobacillus crispatus; a substrate which only lactobacillus crispatus can metabolize is searched based on the genome difference of the two bacteria, and the ability of the obtained substrate for promoting the growth of lactobacillus crispatus and inhibiting the growth of inert lactobacillus is evaluated through experiments. Growth and reproduction of the lactobacillus crispatus are promoted through the substrates, so that the lactobacillus crispatus accounts for a higher proportion in vagina microecology, the vagina is protected, and reproduction of other unfavorable bacteria is reduced. The assisted reproduction success rate is improved.

The invention discloses a lactobacillus helveticus metaplasm complex and application thereof in constipation treatment, and relates to the technical field of constipation treatment, a specific lactobacillus helveticus KLDS 1.1 1105 strain is adopted, and metaplasm is prepared through fermentation and spray drying. The invention further provides a three-layer embedded compound structure. The outer layer is composed of pitaya powder and prune powder and is used for rapidly relaxing the bowels; the middle layer contains a pomegranate peel extract and is used for regulating flora; the core is colon-targeted lactobacillus helveticus metagen and inulin and is used for long-acting regulation. According to the compound, through the multi-target synergistic effect, gastrointestinal hormone is regulated, related signal channels are activated, the function of intestinal pace-making cells is promoted, and generation of short-chain fatty acid is increased, so that the constipation symptom is rapidly relieved, meanwhile, the intestinal function is fundamentally repaired, and the intestinal microecology is improved. The product disclosed by the invention is good in stability, high in safety and suitable for preparing medicines or functional foods for treating functional constipation.

The present invention addresses the problem of providing a composition for controlling bacteria belonging to the genus Fusobacterium among the intestinal flora. The present invention provides a composition for controlling a bacterium belonging to the genus Fusobacterium in the intestinal flora, the composition comprising a bacterium belonging to the family Lactobacillus. The bacterium belonging to the genus fusobacterium is preferably a fusobacterium nucleatum (fusobacterium nucleatum), and the bacterium belonging to the genus fusobacterium is preferably a fusobacterium nucleatum (fusobacterium nucleatum). It is preferable that the bacterium belonging to the family Lactobacillus belong to a bacterium belonging to any genus selected from the group consisting of the genus Lactobacillus, the genus Lactobacillus, the genus Limosilbacilli, the genus Liiilbacilli, the genus Lactobacillus lactis, the genus Lactobacillus casei, and the genus Lactobacillus plantarum, and that the bacterium belonging to the family Lactobacillus is a bacterium belonging to any genus selected from the group consisting of the genus Lactobacillus, the genus Lactobacillus lactis, the genus Lactobacillus acidophilus, the genus Lactobacillus acidophilus, the genus Lactobacillus acidophilus, the genus Lactobacillus acidophilus, the genus Lactobacillus acidophilus and the genus Lactobacillus acidophilus.

The invention relates to the technical field of Bian chicken source lactobacillus sharianus, in particular to Bian chicken source lactobacillus sharianus YYBJ-07-01 as well as a preparation method and application of the Bian chicken source lactobacillus sharianus YYBJ-07-01. The Bian chicken source lactobacillus shariensis YYBJ-07-01 is preserved in the China Center for Type Culture Collection on September 23, 2025, the classification name of the Bian chicken source lactobacillus shariensis YYBJ-07-01 is that the Bian chicken source lactobacillus shariensis YYBJ-07-01 is classified and named, and the preservation number of the Bian chicken source lactobacillus shariensis YYBJ-07-01 is CCTCC (China Center for Type Culture Collection) No.M20252093. As a national protection variety, the strong environmental adaptability of Bian chickens is associated with a unique intestinal microbiome. According to the invention, not only is the precious genetic resource of Bian chicken deeply excavated and scientifically utilized, but also a solid material foundation is laid for developing a Bian chicken source lactobacillus sharianus YYBJ-07-01 product, and the application value of a local characteristic variety is improved.

This invention proposes a molecular marker for *Lactobacillus japonicus*, which was deposited on February 7, 2023, at the China General Microbiological Culture Collection Center (CGMCC) with accession number CGMCC No. 26505. The molecular marker comprises a nucleotide sequence selected from one of the following: (1) the nucleotide sequence shown in SEQ ID NO: 24; (2) a nucleotide sequence having at least 97%, 98%, 99%, or higher homology to the nucleotide sequence shown in SEQ ID NO: 24; or (3) a nucleotide sequence having one or more nucleotide substitutions, deletions, or insertions in the nucleotide sequence shown in SEQ ID NO: 24. Using the molecular marker of this invention, not only can the target *Lactobacillus japonicus* be screened quickly and easily, but it can also highly specifically identify the target *Lactobacillus japonicus*, eliminating interference from other strains.

The invention provides lactobacillus delbrueckii subsp. Bulgaricus LB047 and application thereof in promoting calcium absorption and enhancing immunity, and belongs to the technical field of microorganisms. The invention provides lactobacillus delbrueckii subsp. Bulgaricus LB047, and the preservation number of the lactobacillus delbrueckii subsp. Bulgaricus LB047 is CGMCC No.30725. The invention further provides a preparation method for preparing mushroom peptide fermentation liquor by utilizing the lactobacillus delbrueckii subsp. Bulgaricus LB047, and application of the prepared mushroom peptide fermentation liquor in promoting calcium absorption and enhancing immunity.

The invention belongs to the technical field of microbial genetic engineering, and particularly relates to an acid-resistant lactobacillus plantarum engineering bacterium as well as a construction method and application thereof. The recombinant lactobacillus plantarum WCFS1-gadA-speA is obtained by constructing a recombinant expression vector pMG36e-gadA-speA and inducing the expression of two key genes, and the recombinant lactobacillus plantarum WCFS1-gadA-speA is obtained. The analysis of the fermentation capacity of the strain finds that compared with a single gene heterologous expression strain, the recombinant lactobacillus plantarum WCFS1-gadA-speA shows higher acid resistance and apple juice fermentation capacity. The recombinant lactobacillus plantarum WCFS1-gadA-speA with higher strong acid tolerance is obtained through a heterologous expression technology, a strain resource with better performance is provided for the food fermentation industry, and the quality and stability of a fermented product are improved.

The invention discloses a lactobacillus delbrueckii subsp. Bulgaricus CCFM1520 for transforming curcumin to produce tetrahydrocurcumin to relieve nervous anxiety, and belongs to the technical field of microorganisms. The lactobacillus delbrueckii subsp. Bulgaricus CCFM1520 screened by the invention has the capability of converting curcumin, and can utilize curcumin and generate tetrahydrocurcumin. The invention further provides a synbiotic preparation prepared from the lactobacillus gasseri CCFM1481 and curcumin, the synbiotic preparation can be used as an anti-fatigue functional medicine, the individual behavioral memory level can be improved, the imbalance of body neurotransmitters (DA, 5-HT and NE) can be slowed down, the expression of body neuroprotection related genes (BDNF, TrkB, DRD1 and TH) can be improved, and the synbiotic preparation has a huge application prospect.

The invention discloses a humic acid type straw source microbial agent which comprises the following strains: enterococcus faecium, bacillus subtilis, lactobacillus plantarum and saccharomyces cerevisiae. The method has the advantages that turfy soil, biogas residues, biogas slurry and a certain amount of agricultural waste are added into compost with straw microbial agents and livestock and poultry manure as main materials to adjust a proper carbon nitrogen ratio, and more importantly, a compound microbial agent for strengthening the process of the humic acid type straw source microbial agent is inoculated; compared with natural composting fermentation, the composting efficiency and stability are improved, and the fertilizer efficiency and fertility of the organic fertilizer and the resource utilization efficiency of waste are improved.

The present application provides a kind of microbial inoculum for methane production by straw anaerobic fermentation, belongs to the technical field of microbial fermentation.The microbial inoculum is fermented Lactobacillus mucus and Lactobacillus plantarum.The methane production of the microbial inoculum is 17.64 times compared with the group without microbial inoculum, indicating that the microbial inoculum composed of fermented Lactobacillus mucus and Lactobacillus plantarum can effectively utilize straw anaerobic fermentation to produce a large amount of methane, and the specific synergistic effect between microbial inoculums.The method significantly improves the effect of methane production by promoting the hydrolysis of fermentation substrate, and has the advantages of low cost, sustainability, simple operation and high organic matter utilization rate.

The invention relates to the technical field of biological preparations, and discloses a periodontitis improving compound preparation containing fermented lactobacillus mucus and traditional Chinese medicine extracts, and the periodontitis improving compound preparation comprises the following raw materials: an oral preparation: fermented lactobacillus mucus CQPC202403 bacterial powder; the gel comprises scutellaria baicalensis, honeysuckle, salvia miltiorrhiza, liquorice and a hydrogel matrix; the preservation number of the lactobacillus mucus CQPC202403 in the China General Microbiological Culture Collection Center (CGMCC) is CGMCC NO.31106, and the preservation date of the lactobacillus mucus CQPC202403 is June 27, 2024. The lactobacillus mucilaginosus adopted by the invention inhibits pathogenic bacteria through competitive rejection and immunoregulation; the traditional Chinese medicine extracts such as the radix scutellariae directly destroy bacterial pellicles, and the radix scutellariae and the traditional Chinese medicine extracts cooperate with each other, so that the antibacterial effect is enhanced on the premise of not causing drug resistance.

The invention provides lactobacillus breviscapus for dispelling effects of alcohol and protecting liver and application thereof, and relates to the technical field of biological fermentation, the lactobacillus breviscapus is lactobacillus breviscapus, the strain number of the lactobacillus breviscapus is KMHD10-222, the registration number of the lactobacillus breviscapus in the China General Microbiological Culture Collection Center is CGMCC No.32358, and the number of the lactobacillus breviscapus in the China General Microbiological Culture Collection Center is KMHD10-222. The degradation rate of the lactobacillus brevicornu KMHD10-222 to ethanol with the concentration of 3% reaches 36.05%, the degradation rate of the lactobacillus brevicornu KMHD10-222 to ethanol with the concentration of 7% reaches 19.74%, and the lactobacillus brevicornu KMHD10-222 can degrade ethanol; the lactobacillus brevis KMHD10-222 microbial inoculum has the effect of relieving the acute alcoholic liver injury. The technical problem that in the prior art, probiotics capable of degrading ethyl alcohol and having the effects of dispelling the effects of alcohol and protecting the liver are lacked is solved.