Alph-ketoglutaric acid dehydrase gene

A ketoglutarate dehydrogenase and gene technology is applied in the production field of alpha-ketoglutarate dehydrogenase gene and lysine, and can solve the problem of not finding coryneform bacteria mutants and the like
CN1272437CInactive Publication Date: 2006-08-30AJINOMOTO CO INC
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
AJINOMOTO CO INC
Publication Date
2006-08-30
Estimated Expiration
Not applicable · inactive patent

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Abstract

A coryneform L-glutamate producing bacterium deficient in alpha -ketoglutaric dehydrogenase activity; a process for producing L-glutamic acid by using the bacterium; a gene coding for an enzyme having an alpha -KGDH activity originating in the coryneform L-glutamate producing bacterium; a recombinant DNA containing the above gene; a coryneform bacterium holding the above DNA; and a process for producing L-lysine by using an L-lysine producing bacterium holding the recombinant DNA.
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Description

[0001] This application is a divisional application of the invention patent application with the filing date of June 7, 1995, the application number of 95194559.9, and the invention name of "α-ketoglutarate dehydrogenase gene". technical field

[0002] The invention relates to the cultivation and utilization of coryneform bacteria used for the fermentative production of L-glutamic acid and L-lysine. In particular, the present invention relates to a rod-shaped L-glutamic acid-producing bacterium deficient in α-ketoglutarate dehydrogenase (α-KGDH), a method for producing L-glutamic acid using the bacterium, and a code having The enzyme of α-KGDH activity is also derived from the gene (α-KGDH gene) of coryneform α-glutamic acid-producing bacteria, the recombinant DNA containing the gene, the coryneform bacteria carrying the recombinant DNA and a kind of coryneform bacteria carrying the recombinant DNA and having A method for producing L-lysine with a corynefor...

Claims

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