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Medicinal preparation for treating diabetes and its preparation method

A pharmaceutical preparation and technology for diabetes, which is applied in the field of pharmaceutical preparations for treating diabetes and its preparation, can solve the problems of easy drug resistance, easy rebound of blood sugar, and strong dependence, so as to promote the repair and regeneration of pancreatic islet β cells and protect the liver. Effects on kidney function and prevention of complications

Inactive Publication Date: 2006-11-22
李辉 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] There are many kinds of Chinese and Western medicines for treating diabetes. Metformin, glipizide, Xiaoke pills, etc. are commonly used in clinic. Based on the analysis of domestic and foreign reports, although the effects are quick, they are highly dependent, blood sugar is easy to rebound, and drug resistance is easy to develop. sex

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] 9 parts of coptis, 6 parts of Tianhua powder, 3 parts of yam, 5 parts of Yu Liren, 6 parts of Anemarrhena, 3 parts of Pueraria root, 1 part of Bupleurum, 3 parts of Poria cocos, 0.2 parts of acetylsalicylic acid (aspirin), Glybene 0.006 parts of urea (glyburide) are all parts by weight.

[0025] The preparation method is as follows, all in parts by weight:

[0026] (1) Get 9 parts of Coptis Rhizoma with 0.5% H by weight 2 SO 4 Soak in aqueous solution for 24 hours, extract by percolation, neutralize the acid water leachate with milk of lime, adjust to PH=7, let stand for 48 hours, filter with 400 mesh gauze, add concentrated hydrochloric acid to the filtrate to adjust to PH=2, add 4% by weight of common salt is salted out, and the precipitate is evaporated to dryness in a water bath to obtain the extract of Coptidis rhizome (ie, berberine).

[0027] (2) Take 6 parts of Tianhua Fen, 3 parts of Chinese yam, and 5 parts of Yu Liren, cleanly select, rinse, dry in a steri...

Embodiment 2

[0038] 11 parts of coptis, 5 parts of Tianhua powder, 3 parts of yam, 6 parts of Yu Liren, 5 parts of Anemarrhena, 3 parts of Pueraria root, 2 parts of Bupleurum, 5 parts of Polygonum multiflorum, 0.2 parts of acetylsalicylic acid (aspirin), Glybene 0.005 parts of urea (glyburide) are all parts by weight.

[0039] The preparation method is the same as in Example 1, except that the step (3) does not add Poria cocos, but Polygonum multiflorum.

Embodiment 3

[0041] 12 parts of Coptis chinensis, 8 parts of Tianhuafen, 6 parts of Chinese yam, 6 parts of Yu Liren, 6 parts of Anemarrhena, 5 parts of Pueraria root, 5 parts of Polygonum multiflorum, 0.3 parts of acetylsalicylic acid (aspirin), 0.3 parts of acetylsalicylic acid (aspirin), glibenclamide (glyburide )0.006 parts, all are parts by weight.

[0042] The preparation method is the same as in Example 1, except that the step (3) does not add Poria cocos and Bupleurum bupleuri, but adds Polygonum multiflorum.

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PUM

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Abstract

A medicinal preparation for treating diabetes and a preparation method thereof belong to the technical field of Chinese patent medicines. Including components are: Coptis chinensis, Trichosanthes, Chinese yam and other traditional Chinese medicines, acetylsalicylic acid, and glibenclamide. Extract Coptis chinensis into berberine, grind trichosanthum powder, yam and Yu Liren, decoct and concentrate other medicines to form a paste, mix all the obtained products, dry them, and crush them, then add acetylsalicylic acid powder and glibenclamide powder, and mix well , to obtain a powder; then subdivide into capsules to obtain a capsule. The pharmaceutical preparation for treating diabetes of the present invention has the effects of lowering blood sugar, eliminating urine sugar, promoting the repair and regeneration of pancreatic beta cells, preventing the occurrence of complications in the nervous system and microvascular system, improving and protecting liver and kidney functions, and reducing cholesterol and triglycerides .

Description

(1) Technical field [0001] The invention relates to a medicinal preparation for treating diabetes and a preparation method thereof, belonging to the technical field of Chinese patent medicines. (2) Background technology [0002] Diabetes is a relatively common chronic endocrine and metabolic disorder, which seriously affects people's daily life. The incidence of diabetes in my country has reached 3-4%. In developed countries, its mortality rate is second only to tumors and cardiovascular and cerebrovascular diseases. The third major disease is very difficult to treat and poses a great threat to human physical and mental health, and the incidence rate is increasing year by year. Its complications can lead to life-threatening and difficult to cure. [0003] There are many kinds of Chinese and Western medicines for treating diabetes. Metformin, glipizide, Xiaoke pills, etc. are commonly used in clinic. Based on the analysis of domestic and foreign reports, although the effects a...

Claims

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Application Information

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IPC IPC(8): A61K36/8964A61K36/8945A61K36/736A61K36/718A61K36/48A61K36/428A61K9/14A61K9/48A61P3/10
Inventor 李林福李辉
Owner 李辉
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