Chinese medicine for treating chronic nephritis and its preparation method

A technology for chronic nephritis and traditional Chinese medicine, which is applied in the preparation of tablets or granules, capsules, traditional Chinese medicine for the treatment of chronic nephritis and its preparation field, can solve the problems of long drying time, high rejection rate, long dissolving time, etc. The effect of reducing labor intensity, fewer operators, and reduced dosage

Inactive Publication Date: 2003-09-17
ZHONGJING WANXI PHARMA CO LTD
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AI Technical Summary

Problems solved by technology

There are many opportunities for pill contamination (long exposure time), and the pills are often of different sizes, resulting in inaccurate clinical dosage, and the dissolution time (except for large honeyed pills) is long, about 1 hour;
[0008] 3. If the drying time is too long (generally below 80°C, about 24 hours), the active ingredients of the drug are easily destroyed or volatilized, and the clinical efficacy cannot be effectively guaranteed. There are many chances of pill modification and high scrap rate
[0009] It can be seen from the above that the dosage forms of Jisheng Shenqi Pills are large honeyed pills or water honeyed pills. The technology is backward, the dosage is large and the dosage is not allowed at one time. It is inconvenient to carry and take. It is not suitable for the development of modern Chinese medicine and the needs of people's lives. Therefore, It is necessary to improve the original dosage form

Method used

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Examples

Experimental program
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Effect test

preparation Embodiment 2

[0113] In the production of another batch of medicines, we adopt the following specific processes:

[0114] In the GMP purification workshop, take 80kg of dogwood (manufactured) and 80kg of yam that make up the prescription and grind them into fine powders listed in the "Chinese Pharmacopoeia", that is, the fine powders can all pass through No. 5 sieve (80 mesh) No. 6 sieve (100 mesh) not less than 95% powder, sieved and mixed;

[0115] Take other eight-flavored Chinese herbal medicines: Rehmannia glutinosa 160kg, Poria cocos 120kg, cinnamon 20kg, Alisma 60kg, aconite (manufactured) 20kg, Moutan cortex 60kg, Achyranthes bidentata 40kg, Plantago 40kg, according to the standard specification of "Chinese Pharmacopoeia" 2000 edition concocted, spare;

[0116] Take the processed cinnamon and add 4.5 times the amount of water (w / w), put it in a volatile oil extractor and extract it by steam distillation for 6 hours to obtain volatile oil, distillation mother liquor and remaining me...

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Abstract

A Chinese medicine in the form of capsule, tablet and particle for treating chronic nephritis is prepared from 10 Chinese medicinal materials including rehmannia root, dogwood fruit, yam, tuckahoe, etc. through extracting volatile, nonwater-soluble and alcohol-soluble active components respectively, spray drying and granulating. Its advantages are high curative effect, low dosage, and low toxic by-effect.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparation, and relates to a traditional Chinese medicine for treating chronic nephritis and a preparation method thereof, in particular to a preparation method of capsules, tablets or granules of the traditional Chinese medicine for treating chronic nephritis. Background technique [0002] Chronic nephritis, short for chronic glomerulonephritis, is a group of immune diseases that originate in the glomerulus with similar clinical manifestations, different pathological changes, and different prognosis caused by various reasons. The disease is characterized by proteinuria, hematuria, edema, hypertension and renal insufficiency. It is a common clinical disease, frequently-occurring disease, and has the characteristics of progressive aggravation. As the disease progresses, renal failure occurs in patients more than 2 to 3 years or 20 to 30 years later. According to relevant statistics, th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P13/12
Inventor 高松李长春郭水柱张合营赵小燕赵晓华袁湘平
Owner ZHONGJING WANXI PHARMA CO LTD
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