Interferon series daily-use chemical products with virus-killing action and its production process

A technology of chemical products and interferon, applied in the direction of chemical instruments and methods, detergent compounding agents, detergent compositions, etc., can solve the problems of easy inactivation, inactivation of viruses, and no detection, etc., and achieve the use method Simple, effective in preventing the spread of infection

Inactive Publication Date: 2003-12-10
CHANGCHUN CHANGSHENG GENE ENG TECH INST
View PDF0 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, since interferon is a biological macromolecule, its stability is poor and it is easy to be inactivated. If the interferon component is simply added to daily chemical products such as toothpaste, the interferon is easily inactivated, and the effect of inactivating the virus cannot be achieved. effect
After searching, there is no report on a series of daily-use chemical products that have anti-virus effects, especially on SARS virus

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Alpha-interferon toothpaste:

[0023] Glycerin 17.0%, saccharin 0.2%, calcium hydrogen phosphate 1.3%, formaldehyde solution 0.2%, sodium lauryl sulfate K12, carboxymethyl cellulose CMC 0.8%, calcite powder 53.0%, essence amount, deionized water balance , α-interferon 0.0001 ~ 0.1%;

[0024] Preparation of interferon liposomes:

[0025] Oil phase: Take 1.2 g of phospholipids, 0.3 g of cholesterol, 0.2 g of polysorbate 80 (surfactant), 3 ml of absolute ethanol, melt in a water bath at 75°C.

[0026] Water phase: Take 2.8 grams of dextran (sugar protecting agent), 50 ml of phosphate buffer, pour the interferon into the water phase cooled to 40°C, mix well and pour into the oil phase at 40°C, shake and sonicate Treat for 2 minutes, pre-freeze overnight at -30°C, and freeze-dry to prepare α-interferon liposomes.

[0027] Appropriate amount of stabilizer; other items should meet the relevant regulations of the toothpaste industry.

[0028] Prepared according to the conve...

Embodiment 2

[0030] Omega Interferon Soap:

[0031] Coral powder 13.7%, fatty acid sodium 21.85%, surfactant 1.14%, water 20.01%, sodium alginate 13.7%, glycerin 2.85%, sucrose 6.66%, sodium chloride 6.85%, hydroxyethanediphosphate 0.1%, ethanol 13.13% %, ω-interferon 0.001-0.1%, appropriate amount of stabilizer, and other items should meet the relevant regulations of the soap industry.

[0032] Preparation of interferon liposomes:

[0033] Oil phase: take 0.95 g of lecithin, 0.5 g of cholesterol, 0.3 g of Span 80 (surfactant), and 0.3-3 ml of absolute ethanol and melt in a 75°C water bath.

[0034] Water phase: Take 2.8 grams of trehalose (sugar protecting agent). , 40 ml of phosphate buffer, pour ω-interferon into the water phase cooled to 40°C, mix well, pour into the oil phase at 40°C, shake and sonicate for 2 minutes, pre-freeze overnight at -30°C, and freeze-dry That is, make omega interferon liposome.

[0035] Stir all the components to make them completely mix and dissolve, the...

Embodiment 3

[0037] Beta-Interferon Moisturizing Gel Water:

[0038] Polyvinylpyrrolidone (PVP) 3.5%, chitin NMF 2.0%, water-soluble silicone oil 1.0%, acetylated lanolin 10.5%; carbo resin 0.8%, triethanolamine 0.2%, polyethylene glycol 4000.5%, appropriate amount of essence, Cathone 0.2%, propylene glycol 1.0%, water balance, β-interferon 0.01-0.1%, stabilizer amount; other items should meet the relevant regulations of the hair products industry.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The present invention discloses a kind of interferon series daily-used chemical product, and its preparation method includes the following steps: firstly, preparing interferon raw liquor, placing it into lecithin / cholesterol to make emulsification to obtain interferon liposome; then mixing and dissolving raw materials for making daily-used chemical product, and adding prepared alpha-interferon or beta-interferon or owega-interferon liposome into the above-mentioned mixed and dissolved raw material, vacuum deoerating and stirring to a certain temp. so as to obtain the invented product with action of killing virus. Said product can be used for brushing tooth, rinsing, mouth and washing hand, and can prevent infection of virus, including SARS virus.

Description

Technical field: [0001] The invention relates to a daily-use chemical product capable of killing viruses including SARS virus. Specifically, it provides a series of daily-use chemical products of interferon with the effect of killing viruses, and at the same time provides its production process, which belongs to the daily-use chemical industry. Product and preparation technology field. Background technique: [0002] Viruses, especially SARS virus, are caused by transmission through the respiratory tract (nose-mouth) and contact. Therefore, it is difficult to control its transmission. Usually, drug sprays, nasal drops, etc. are used, but they are not comprehensive and thorough. An effective and convenient method for preventing virus infection has become a top priority. Daily chemicals are directly applied to human skin, oral cavity, and hair, and have real-time action functions, which can be used as a good measure for implementing antiviral drugs. However, since interferon ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): C11D3/48
Inventor 王茂祥张士安冯秀萍杨倩杨美华谷冉峰
Owner CHANGCHUN CHANGSHENG GENE ENG TECH INST
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap