Mouth cavity quick dissolving quick disintegrating freeze-dried tablet and its preparing method

Abstract

The oral cavity quick dissolving and quick disintegrating freeze dried tablet for children includes at least one medicinal active component and at least one medicinal stuffing, adhesive and other supplementary material. It is loose and porous tablet in network structure and prepared through common freeze drying process. The said medicinal active component may be different children's medicines, such as antibiotic, antipyretic, analgesic, cough stopping and phlegm eliminating medicine, cold medicine, etc. Bitter or excitant medicine may be coated and water insoluble medicine is prepared intofine powder of 50 micron below size for stable dispersion in liquid. The present invention has fast disintegration, no jamming in throat, simple preparation process and low cost.

Description

technical field

[0001] The invention relates to a pharmaceutical dosage form, in particular to an oral instant-dissolving and rapidly disintegrating freeze-dried tablet for children and a preparation method thereof. Background technique

[0002] As we all know, it is troublesome to let preschool children (especially infants under 3 years old) take pills orally. When feeding the medicine, the children cry and make parents anxious. In order to solve the above-mentioned problem of oral administration to children, manufacturers have developed many oral pharmaceutical dosage forms that are convenient for children to use, such as granules, chewable tablets, dispersible tablets, effervescent tablets and various liquid preparations. Although the above-mentioned pharmaceutical preparations have improved the compliance and convenience of children's oral administration to a certain extent, there are still deficiencies. Many infants and young children have already felt when their paren...