Zanthoxylam bungeanum seed kernel oil and kudzu vine root alcohol extract series medicament and preparing process thereof

Abstract

The invention is a compound series medicament of Prickly ash seed embryo kernel oil and Radix pueraiae alcohol extract and the preparing technique, providing the series preparatins such as oral liquid, tablet and capsule to cure cardiovascular and cerebrovascular diseases, its main formula including Prickly ash seed embryo kernel oil and total Radix Pueraiae totae flavone. It first makes medicinal Prickly ash seed embryo kernel oil, at the same time extract total said flavone(extract, glucoside powder) by alcohol-extracting technique and puerarin, compound Prickly ash seed embryo kernel oil and Radix Pueraiae alcohol extract and then use Chinese patent drug processing technique to produce series Chinese patent drug.

Description

Technical field: [0001] The series of medicaments combined with pepper seed germ kernel oil and kudzu root ethanol extract and the preparation process thereof belong to the medicine for treating cardiovascular and cerebrovascular diseases and the preparation process thereof, and especially relate to the compound Chinese medicine preparation and its series of products which are combined with the extracted components of Chinese medicinal materials Preparation Process. Background technique [0002] The treatment, prevention and drug development of cardiovascular and cerebrovascular diseases represented by hypertension, coronary heart disease and cerebral thrombosis are the focus of the modernization of traditional Chinese medicine at home and abroad. The main Chinese medicinal materials used in traditional medicine are salvia miltiorrhiza, ginkgo, kudzu root, chuanxiong, hair holly, hawthorn , safflower, perilla, seabuckthorn, flax, amaranthus, etc., but the content of its medi...

AI Technical Summary

Problems solved by technology

[0002] The treatment, prevention and drug development of cardiovascular and cerebrovascular diseases represented by hypertension, coronary heart disease and cerebral thrombosis are the focus of the modernization of traditional Chinese medicine at home and abroad. The main Chinese medicinal materials used in traditional medicine are salvia miltiorrhiza, ginkgo, kudzu root, chuanxiong, hair holly, hawthorn , safflower, perilla, seabuckthorn, flax, amaranthus, etc., but the content of its medicinal ingredients is low, low curative effect and repeated drug development, especially traditional Chinese patent medicines. High, expensive, long-term use of patients with a heavy economic burden, because the treatment range is narrow, the curative effect is not outstanding, it is difficult to adapt to the selection of patients with different cardiovascular and cerebrovascular diseases

Since it was confirmed that α-linolenic acid can generate EPA (20:5N-3) and DHA (22:6N-3) through dehydrogenation in the human body, domestic and foreign medicinal materials rich in α-linolenic acid, safflower, purple Extracting fatty acid oil from plant seeds such as perilla and seabuckthorn to replace deep-sea fish oil to develop new drugs for treating cardiovascular and cerebrovascular diseases became a hot spot, but according to "Modern Research and Clinical Application of Traditional Chinese Medicine" published by Xueyuan Press in October 1993, edited by Yin Jian and Guo Liqiang Relevant information on pages 332, 378 and 633 of the book proves that the safflower extract has obvious mutagenic effect, seabuckthorn oil and total flavonoids of seabuckthorn have strong cumulative toxicity, and perilla contains toxic eugenol , α-pinene, and perillyl alcohol, the toxic and side effects have become obstacles to the development of the above-mentioned Chinese medicinal materials to develop national second-class new drugs of traditional Chinese medicine