Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Xingnaojing powder injection and preparing method

A technology of powder injection and Xingnaojing, which is applied in the field of Xingnaojing powder injection and its preparation, can solve the problems affecting the quality and safety of preparations, and achieve the effects of long-term storage, reduced chance of pollution, and low water content

Inactive Publication Date: 2005-05-18
BEIJING BOERDA BIO TECH DEV
View PDF2 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chinese patent CN1457798 discloses a method for zedoary oil to be encapsulated by hydroxypropyl-β-cyclodextrin and then prepared into a freeze-dried powder injection. However, this method uses an organic solvent to dissolve the volatile oil and then encapsulates it with hydroxypropyl-β-cyclodextrin. combination, the residue of organic solvent will affect the quality and safety of the preparation

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 8

[0018] The following examples are used to further illustrate the present invention, but not to limit the scope of the present invention.

Embodiment 1

[0020] Prescription: Musk 7.5g

[0021] Turmeric 30g

[0022] Gardenia 30g

[0023] borneol 1g

[0024] Polysorbate 80 8g

[0025] Hydroxypropyl-β-cyclodextrin 150g

[0026] Sodium chloride 8g

[0027] Add water for injection to 1000ml

[0028] A total of 500 pieces were made

[0029] Preparation method: distill turmeric and gardenia with about 1500ml of water, collect 1000ml of distillate, add musk to the above distillate, add 250ml of distilled water for distillation, collect 1000ml of distillate, and set aside; take borneol, add 8g of polysorbate 80 , grind evenly, add to the distillate, mix well, stir to dissolve, then add 8.0g sodium chloride, after dissolving, mix well, place, refrigerate overnight to obtain an aromatic aqueous solution containing extract, then add hydroxypropyl-β -Cyclodextrin, stir and clathrate for 2 hours, place at room temperature, add activated carbon, absorb, de...

Embodiment 2

[0037]Prescription: Musk 7.5g

[0038] Turmeric 30g

[0039] Gardenia 30g

[0040] borneol 1g

[0041] Polysorbate 80 8g

[0042] Hydroxypropyl-β-cyclodextrin 50g

[0043] Sodium chloride 8g

[0044] Mannitol 100g

[0045] Add water for injection to 1000ml

[0046] A total of 500 pieces were made

[0047] Preparation method: distill turmeric and gardenia with about 1500ml of water, collect 1000ml of distillate, add musk to the above distillate, add 250ml of distilled water for distillation, collect 1000ml of distillate, and set aside; take borneol, add 8g of polysorbate 80 , grind well, add to the distilled liquid, mix well, stir to dissolve, then add 8.0g sodium chloride, after dissolving, mix well, place, refrigerate overnight to obtain an aromatic aqueous solution containing the extract, then add hydroxypropyl-β - Cyclodextrin, ultrasonic clathrate for 2 hours, place at room te...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present invention features that main medicine material including musk, curcuma root and cape jasmine extract and borneol are prepared into aromatic water solution, and the aromatic water solution is included with hydroxypropyl-beta-cyclodextrin and freeze driedor spray dried to prepare Xingnaojing powder for intravenous injection. The Xingnaojing powder for intravenous injection is superior to Xingnaojing injection in that it has the advantages of no high temperature decomposition of medicine component, high stability and less pollutant in product.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, specifically Xingnaojing powder injection and a preparation method thereof. Background technique [0002] Xingnaojing Injection is a water-soluble intravenous injection formulated on the basis of the ancient prescription Angong Niuhuang Pills. It is administered intravenously and has the effects of refreshing the brain and relieving convulsions. The main ingredients of the medicine are musk, borneol, gardenia, turmeric and so on. Indications: Xingnaojing has a wide range of clinical effects, and has a significant therapeutic effect on cerebrovascular accidents, disturbance of consciousness caused by central nervous system infection, convulsions, and cerebral palsy caused by neonatal cerebral hypoxia. , Xingnaojing can also be used to treat various encephalitis, meningitis, high fever caused by various reasons, sleeping pills, ramifen, alcoholism and other diseases. Pharmacological a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K9/14A61P25/00A61P43/00
Inventor 张成飞孟旻
Owner BEIJING BOERDA BIO TECH DEV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com