Vagina effervescent tablets contg. callicarpa nudiflora, and its prepn. method

A technology of naked flower purple beads and effervescent tablets is applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and drug delivery, etc. Acceptable, easy-to-use effects

Inactive Publication Date: 2006-01-25
石药集团中诺药业(石家庄)有限公司
View PDF0 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As a gynecological topical drug, suppositories have the disadvantage of being easily deformed and sticking to hands when used

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] A. Preparation of Naked Flower Purple Pearl Extract Powder: Cleanly select 2000g of naked flower purple pearl medicinal materials to remove impurities. Adding water for the first time is 14 times the amount of the drug, and the second and third times are 10 times the amount of the drug. Combine the decoction, filter, and concentrate the filtrate to a clear paste with a relative density of 1.28-1.32 (60-65°C). Press and dry into a dry paste; preferably controlled at 80°C; crush the dry paste into a fine powder to obtain the naked flower purple pearl extract powder.

[0021] In the preparation method of the above-mentioned purple pearl extract powder, the decoction filtrate can also be concentrated into a concentrated solution with a relative density of 1.08 to 1.10 (60 to 65°C), spray-dried into a dry cream powder, and the temperature of the spray-dried air inlet is 100°C. ~200°C, the outlet air temperature is 50~100°C, the optimum temperature is 160°C, and the outlet ai...

Embodiment 2

[0034] (1) Prescription:

[0035] Naked Flower Purple Pearl Extract Powder 432g

[0036] Tartaric acid 110g

[0037] Sodium bicarbonate 65g

[0038] Sodium carbonate 40g

[0039] Microcrystalline Cellulose 100g

[0040] Mannitol 236g

[0041] PEG4000 17g

[0042] Makes 1000 pieces

[0043] (2) Preparation method: dry and pulverize tartaric acid, sodium bicarbonate, sodium carbonate, crystal cellulose, mannitol, and PEG4000 respectively according to the above-mentioned component distribution ratio and cross a 100-mesh sieve; Add 65g of sodium bicarbonate, 40g of sodium carbonate, and 100g of microcrystalline cellulose to one part, mix well, use 5% PVP ethanol solution as a binder, make granules, dry, and granulate at 40 mesh; another part adds 110g of tartaric acid , mannitol 236g, mix well, use 5% PVP ethanol solution as binder, make granules, dry, granulate with 40 meshes; mix the two kinds of granules together, add dry PEG400017g, mix well; compress with tablet machin...

Embodiment 3

[0045] (1) Prescription:

[0046] Naked Flower Purple Pearl Extract Powder 432g

[0047] Fumaric acid 115g

[0048] Sodium bicarbonate 55g

[0049] Potassium carbonate 35g

[0050] Powdered sugar 338g

[0051] PEG4000 20g

[0052] Magnesium Stearate 5g

[0053] Makes 1000 pieces

[0054] (2) Preparation method: Dry fumaric acid, sodium bicarbonate, potassium carbonate, powdered sugar, PEG4000, and magnesium stearate respectively according to the above-mentioned composition ratio, and pulverize them through a 100-mesh sieve; 55g of sodium bicarbonate, 35g of potassium carbonate, 169g of powdered sugar, mix well, use 5% PVP ethanol solution as binder, make granules, dry, granulate with 40 mesh; 115g acid, 169g powdered sugar, mix well, use 5% PVP ethanol solution as binder, make granules, dry, granulate with 40 mesh; mix the two kinds of granules together, add dry PEG4000 20g, magnesium stearate 5g, Mix well; use a tablet machine to compress into diamond-shaped tablets, ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

A vaginal effervescent tablet with high release speed and no irritation is prepared from achamydeous beautyberry leaf, effervescent agent and auxiliary. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a naked flower purple pearl vaginal effervescent tablet and a preparation method thereof, belonging to a pharmaceutical preparation method [0002] technology field. Background technique [0003] Vaginal effervescent tablets are a new form of traditional Chinese medicine. According to the relevant drug laws and regulations of our country, changing the dosage form is regarded as a new drug research. The extract of Nudehuazizhu has many dosage forms, and the external dosage form of Nudehuazizhu suppository has been listed in the national Compilation of National Standards of Chinese Patent Medicine by Food and Drug Administration. As a gynecological external drug, suppositories have the disadvantage of being easily deformed and sticking to hands during use. Contents of the invention [0004] The technical problem to be solved by the present invention is that we use modern pharmaceutical technology to improve the production pro...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/85A61K9/20A61K9/46A61P15/02
Inventor 梁纪军李勇郭惠娟康丽霞
Owner 石药集团中诺药业(石家庄)有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap