Methylamino avermectin benzoate soluble granule and preparation method thereof
A technology of methylamino abamectin and benzoate, applied in the field of high-efficiency methylamino abamectin benzoate soluble granules and preparation fields, can solve the problem of insufficient content of the original drug, short drug shelf life, composition Many ingredients, etc., to achieve the effects of convenient transportation and storage, good water solubility, and improved resistance to radiation and light.
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[0006] An example is given below to describe in detail.
[0007] Weigh respectively 180 grams of emamectin benzoate technical material, 70 grams of β-cyclodextrin, 150 grams of nonylphenol polyoxyethylene ether NP40 surfactant, sodium dodecylsulfonate ABS- 80 grams of Na surfactant, 250 grams of sodium bicarbonate, 270 grams of anhydrous citric acid, a total of 1000 grams for subsequent use, the percentages of each component accounting for the total weight are 18%, 7%, 15%, 8%, 25%, 27% %, totaling 100%. When making, first mix the former medicine of 180 grams of emamectin benzoate with 70 grams of β-cyclodextrin and 80 grams of sodium dodecylsulfonate ABS-Na surfactant in the 50 ℃ water, using a high-pressure homogenizer at 400 kg / cm 2 Stir and homogenize under high pressure; send the homogenized above-mentioned liquid mixture into a spray drying tower for spray drying to make a composite master drug; heat-melt 150 grams of nonylphenol polyoxyethylene ether NP40 surfactant i...
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