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Kidney-tonifying and bone-strengthening capsules and preparation thereof

A technology for invigorating the kidney and strengthening bones and soft capsules, which are used in capsule delivery, bone diseases, pharmaceutical formulations, etc., can solve the problems of unreasonable application for protection and lack of in-depth experimental research, and achieve improved compliance, beautiful appearance, and ease of use. effect of swallowing

Inactive Publication Date: 2007-04-04
张勇 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] "Xianlinggubao new preparation and its preparation method and use" (publication number CN1634293A) covers other dosage forms of Xianlinggubao except tablets and capsules, and we found that no in-depth experimental research has been carried out on it. , at the same time, it is unreasonable to apply for protection for the disclosed process prescription (which has been disclosed in the national standard)

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Contents recipe:

[0031] Components: weight per grain (mg) weight ratio (%)

[0032] Danshen fine powder 83 13.8

[0033] Concentrated Clear Cream 217 36.2

[0034] PEG400 275 45.8

[0035] Tween 80 15 2.5

[0036] Beeswax 10 1.7

[0037] Gross weight 600

[0038] Capsule recipe:

[0039] Components: Weight (grams) Weight ratio (%)

[0040] Gelatin 10750 43

[0041] Glycerin 4500 18

[0042] Water 8878 38.1

[0043] Methylparaben 20 0.08

[0044] Propylparaben 5 0.02

[0045] Iron oxide red 160 0.64

[0046] Titanium dioxide 25 0.1

[0047] Gross weight 25000

[0048] The content preparation process is as follows:

[0049] Grind Salvia Miltiorrhiza into fine powder, sieve it, and set aside; grind the four medicinal materials such as Epimedium, Dipsacus, Anemarrhena, and Psoralen into coarse powder, cut Rehmannia glutinosa into thin slices, add water and boil three times, the first time for 3 hours, The second time is 2 hours, the third time is 1 hour, t...

Embodiment 2

[0055] Contents recipe:

[0056] Components: weight per grain (mg) weight ratio (%)

[0057]Danshen fine powder 83 13.8

[0058] Concentrated Clear Cream 217 36.2

[0059] PEG400 240 40

[0060] PEG6000 10 1.7

[0061] Tween 80 30 5

[0062] Beeswax 20 3.3

[0063] Gross weight 600

[0064] Capsule recipe:

[0065] Components: Weight (grams) Weight ratio (%)

[0066] Gelatin 11250 45

[0067] Glycerin 5500 22

[0068] water 8020 32

[0069] Methylparaben 30 0.12

[0070] Propylparaben 7.5 0.03

[0071] Iron oxide red 160 0.64

[0072] Titanium dioxide 32.0.13

[0073] Gross weight 25000

[0074] Prepare as in Example 1.

Embodiment 3

[0076] Contents recipe:

[0077] Components: weight per grain (mg) weight ratio (%)

[0078] Danshen fine powder 83 11.9

[0079] Extract 178 25.4

[0080] Soybean oil 340 48.6

[0081] Polyoxyethylene castor oil 63 9

[0082] Glyceryl monostearate 36 5.1

[0083] Gross weight 700

[0084] Capsule recipe:

[0085] Components: Weight (grams) Weight ratio (%)

[0086] Gelatin 11750 47

[0087] Glycerin 6750 27

[0088] water 6258 25

[0089] Ethylparaben 36 0.144

[0090] Propylparaben 9 0.036

[0091] Iron oxide red 160 0.64

[0092] Titanium dioxide 37.5 0.15

[0093] Gross weight 25000

[0094] Prepare as in Example 1.

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PUM

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Abstract

A Chinese medicine 'Xianling Gubao softgel' for nourishing kidney and strengthening bone is prepared from fine powder of red sage root, the powdered extracts of 5 Chinese-medicinal materials including epimedium, dipsacus root, rehmannia root, etc, and the medicinal auxiliary chosen from vegetative oil, polyethanediol, and glycol monoethylether.

Description

technical field [0001] The invention relates to a new dosage form of traditional Chinese medicine and a preparation method thereof, in particular to a traditional Chinese medicine soft capsule for invigorating the kidney and strengthening bones and a preparation method thereof. Background technique [0002] The traditional Chinese medicine Xianling Gubao is a compound preparation composed of six traditional Chinese medicines such as Epimedium, Dipsacus, Salvia, Anemarrhena, Psoralen, and Dihuang. It is used to treat osteoporosis caused by liver and kidney deficiency and blood stasis blocking collaterals. , suitable for nourishing the kidney and strengthening the bones. [0003] The products currently on the market include hard capsules and tablets, both of which are produced by Guizhou Tongjitang Pharmaceutical Co., Ltd. Tablets are the main product, which are sugar-coated tablets. The market sales are stable and they have a high reputation among domestic traditional Chinese...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61K36/185A61K36/804A61K36/53A61K36/296A61K36/487A61K9/48A61P19/10
Inventor 张勇陆兔林
Owner 张勇
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